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Aifm1
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Rattus norvegicus
Aifm1 is differentially expressed in 65 experiments: 63 organism parts: frontal cortex, hippocampus, ... (61 more);, 8 disease states: normal, BDL 7 days, ... (6 more);, 8 cell types 13 compound treatments 8 clinical treatments and 13 other conditions.
Synonyms Pdcd8, Aif
Orthologs AIFM1 (Homo sapiens)   Aifm1 (Mus musculus)   AIFM1 (Gallus gallus)   ENSCING00000005922 (Ciona intestinalis)   pdcd8 (Danio rerio)   AIF (Drosophila melanogaster)   aifm1 (Xenopus laevis)   (Compare orthologs)
Gene Ontology Term cytosol, oxidoreductase activity, DNA binding, protein binding, mitochondrial inner membrane, cytoplasm, cell redox homeostasis, membrane, mitochondrial intermembrane space, activation of caspase activity, soluble fraction, microsome, nucleus, electron carrier activity, perinuclear region of cytoplasm, DNA fragmentation involved in apoptotic nuclear change, neuron apoptosis, mitochondrion, apoptosis in response to endoplasmic reticulum stress, oxidation-reduction process, flavin adenine dinucleotide binding
InterPro Term Pyridine_nuc-diS_OxRdtase_2, FAD/NAD-linked_Rdtase_dimer, FAD_pyr_nucl-diS_OxRdtase, Hg_reductase, Pyr_nucl-diS_OxRdtase_FAD/NAD, Pyr_OxRdtase_NAD-bd_dom
UniProt Accession Q9JM53
Search EB-eye ENSRNOG00000006067
Show more properties
Experimental Factors
Organism part

studied in E-GEOD-15184, E-GEOD-19830, E-GEOD-20388, E-AFMX-7, E-GEOD-471, ... (19 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell type

studied in E-MEXP-31, E-GEOD-1567, E-TABM-130

Factor Value U/D Experiments
Sertoli cell
1
2
E-MEXP-31, E-TABM-130
alveolar epithelial type II
1
E-GEOD-1567
spermatid
1
E-TABM-130
spermatogonia
1
E-MEXP-31
alveolar epithelial type I
1
E-GEOD-1567
spermatide
1
E-MEXP-31
2 more value(s).


Disease state

studied in E-GEOD-1872, E-GEOD-594, E-GEOD-464, E-GEOD-4745, E-MTAB-104, ... (6 experiments)

Factor Value U/D Experiments
mild spinal cord injury
1
E-GEOD-464
breast carcinoma
1
E-GEOD-1872
Sham
1
E-MEXP-2583
normal
2
2
E-MTAB-104, E-GEOD-1872, E-GEOD-4745, E-GEOD-594
bone fracture
1
E-GEOD-594
diabetes mellitus
5
1
E-GEOD-4745
2 more value(s).


Compound treatment

studied in E-GEOD-691, E-GEOD-5509, E-MEXP-2098, E-GEOD-424, E-GEOD-2331, ... (10 experiments)

Factor Value U/D Experiments
none
1
3
E-GEOD-2331, E-MEXP-2098, E-GEOD-691, E-GEOD-4745
butyrate
1
E-GEOD-424
interleukin 1 beta and glucosamine
1
E-GEOD-6119
clofibric acid
1
E-GEOD-691
LG100268
1
E-GEOD-2331
clofibrate
1
E-GEOD-2303
7 more value(s).


Clinical treatment

studied in E-GEOD-7002, E-GEOD-738, E-GEOD-1685, E-MTAB-104

Factor Value U/D Experiments
sham implantation
1
E-MTAB-104
none
1
E-GEOD-1685
no implantation
1
E-MTAB-104
instillation
1
E-GEOD-7002
implanted tumor
1
E-MTAB-104
av-fistula - sham
1
E-GEOD-738
2 more value(s).


compound_treatment_design

studied in E-TABM-12

Factor Value U/D Experiments
17a-ethynylestradiol
1
E-TABM-12
genestein
1
E-TABM-12


Day
studied in E-GEOD-20659

Developmental stage
studied in E-MEXP-570, E-GEOD-903, E-GEOD-20245

Fluidics machine
studied in E-TABM-536

Growth condition
studied in E-GEOD-6102, E-GEOD-1567, E-TABM-501

Injury
studied in E-MEXP-1387

Material type
studied in E-MEXP-2527

Phenotype
studied in E-GEOD-2275

protocol
studied in E-GEOD-20895

Protocol type
studied in E-GEOD-1616, E-MEXP-1565

Strain or line
studied in E-MTAB-322, E-TABM-457, E-GEOD-952, E-MTAB-323

Test result
studied in E-GEOD-4745

Treatment
studied in E-GEOD-16981, E-GEOD-19909

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM