Grb2
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Rattus norvegicus |
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Grb2 is differentially expressed in 75 experiments: 59 organism parts: amygdala, kidney, ... (57 more);, 4 disease states: normal, bladder carcinoma, ... (2 more);, 8 cell types 1 cell lines 276 compound treatments and 20 other conditions. |
| Synonyms |
MGC108668 |
| Orthologs |
GRB2 (2 of 2)
(Danio rerio)
grb2
(Danio rerio)
Grb2
(Mus musculus)
GRB2
(Homo sapiens)
A3R0S3_CHICK
(Gallus gallus)
grb2
(Xenopus tropicalis)
ENSCING00000016031
(Ciona intestinalis)
(Compare orthologs)
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| Ensembl Family Description |
GROWTH FACTOR RECEPTOR BOUND 2 ADAPTER GRB2 SH2/SH3 ADAPTER GRB2 |
| Gene Ontology Term |
cytosol, vesicle membrane, protein binding, cytoplasm, protein complex, membrane, Golgi apparatus, insulin receptor signaling pathway, insulin receptor substrate binding, protein domain specific binding, receptor internalization, ephrin receptor binding, epidermal growth factor receptor binding, fibroblast growth factor receptor signaling pathway, cell differentiation, regulation of MAPKKK cascade, Ras protein signal transduction, nucleus, aging, SH3/SH2 adaptor activity, endosome, phosphoprotein binding, branching involved in embryonic placenta morphogenesis, anatomical structure formation involved in morphogenesis, phosphotyrosine binding, protein phosphatase binding, protein heterooligomerization, positive regulation of reactive oxygen species metabolic process, signal transduction in response to DNA damage, cellular response to ionizing radiation, neurotrophin TRKA receptor binding |
| Gene Ontology ID |
GO:0008286, GO:0016020, GO:0007265, GO:0008543, GO:0007568, GO:0051219, GO:0005515, GO:0012506, GO:0005737, GO:0005634, GO:0005829, GO:0005794, GO:0005768, GO:0005154, GO:0005070, GO:0019904, GO:0031623, GO:0046875, GO:0043234, GO:0043560, GO:0043408, GO:0030154, GO:0060670, GO:0051291, GO:0048646, GO:0042770, GO:0019903, GO:0001784, GO:0071479, GO:2000379, GO:0005168 |
| InterPro ID |
IPR000108, IPR001452, IPR011511, IPR000980, IPR013315 |
| Ensembl Family |
ENSFM00500000270097 |
| RefSeq ID |
NP_110473, NM_030846 |
| EMBL-Bank ID |
D49847, D49846, X62853, BC091144 |
| Ensembl Protein ID |
ENSRNOP00000005347, ENSRNOP00000043863 |
| UniGene ID |
Rn.199592, Rn.3360 |
| RGD ID |
619758 |
| UniProt Accession |
P62994, F1LTH1 |
| Entrez Gene ID |
81504 |
| RGD Symbol |
Grb2 |
| Ensembl Gene ID |
ENSRNOG00000003990 |
| Ensembl Transcript ID |
ENSRNOT00000043473, ENSRNOT00000005347 |
| Description |
Growth factor receptor-bound protein 2 [Source:UniProtKB/Swiss-Prot;Acc:P62994] |
| InterPro Term |
SH2 motif, Neutrophil cytosol factor 2 p67phox, Src homology-3 domain, Spectrin alpha chain, SH3 domain, Variant SH3 |
| Design Element |
rc_AI170776_s_at, 6252514, 6176821, 6003656, 6348946, 1368386_at, ENSRNOT00000043473, 1368385_a_at, 6728959, rc_AA801130_at, ENSRNOT00000005347, 6533420, 6533432, 5907758, 5810699, 6674437, 6112512 |
| EMAGE ID |
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| Search EB-eye |
ENSRNOG00000003990
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