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Ccnd1
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Mus musculus
Ccnd1 is differentially expressed in 319 experiments: 119 organism parts: liver, kidney, ... (117 more);, 19 disease states: normal, 3-NP-induced neurodegeneration model of Huntington's disease, ... (17 more);, 60 cell types 27 cell lines 56 compound treatments and 46 other conditions.
Synonyms 'cD1', 'PRAD1', 'Cyl-1', 'bcl-1'
Orthologs F1NS84_CHICK (Gallus gallus)   F6S8K9_CIOIN (Ciona intestinalis)   Ccnd1 (Rattus norvegicus)   CCND1 (Homo sapiens)   CCND1_BOVIN (Bos taurus)   CycD (Drosophila melanogaster)   ccnd1 (Xenopus laevis)   (Compare orthologs)
Gene Ontology Term cytosol, cell division, cyclin-dependent protein kinase regulator activity, regulation of phosphorylation, protein binding, cytoplasm, intracellular, regulation of catalytic activity, positive regulation of cell proliferation, membrane, regulation of cyclin-dependent protein kinase activity, negative regulation of Wnt receptor signaling pathway, cell cycle, Wnt receptor signaling pathway, regulation of cell cycle, protein kinase binding, G1/S transition of mitotic cell cycle, nucleus, canonical Wnt receptor signaling pathway, kinase activity, response to drug, nucleoplasm, response to DNA damage stimulus, response to X-ray, endoplasmic reticulum unfolded protein response, response to ethanol, enzyme binding, protein kinase activity, response to corticosterone stimulus, mammary gland epithelial cell proliferation, response to magnesium ion, response to vitamin E, response to organic nitrogen, lactation, response to iron ion, response to calcium ion, positive regulation of mammary gland epithelial cell proliferation, fat cell differentiation, response to UV-A, re-entry into mitotic cell cycle, response to estrogen stimulus, organ regeneration, positive regulation of cyclin-dependent protein kinase activity, liver development, response to organic substance, negative regulation of epithelial cell differentiation, mammary gland alveolus development, protein complex binding, cyclin-dependent protein kinase holoenzyme complex, response to steroid hormone stimulus, cellular response to organic substance, response to glucocorticoid stimulus, Leydig cell differentiation, protein phosphorylation, positive regulation of protein phosphorylation, mitotic cell cycle G1/S transition DNA damage checkpoint, response to organic cyclic compound
InterPro Term Cyclin-like, Cyclin_N, Cyclin_C, Cyclin_A/B/D/E
Search EB-eye ENSMUSG00000070348
Show more properties
Experimental Factors
Organism part

studied in E-TABM-1039, E-GEOD-1479, E-GEOD-20160, E-GEOD-3963, E-GEOD-2161, ... (61 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-17112, E-GEOD-21515, E-GEOD-19732, E-GEOD-1956, E-GEOD-10246, ... (9 experiments)

Factor Value U/D Experiments
H-59
1
E-MEXP-1361
lewis lung carcinoma (LLC)
1
E-GEOD-17112
N1E-115 wild_type
1
E-GEOD-1956
RAW264
1
E-MEXP-2554
N1E-115 Tcof1 overexpressed
1
E-GEOD-1956
IP36D-3
1
E-GEOD-21515
21 more value(s).


Cell type

studied in E-GEOD-2585, E-GEOD-7764, E-GEOD-7069, E-GEOD-21749, E-GEOD-272, ... (31 experiments)

Factor Value U/D Experiments
hematopoietic stem cell
4
E-GEOD-7069, E-GEOD-20377, E-MEXP-1158, E-GEOD-6623
round spermatid
2
E-GEOD-21749, E-GEOD-4193
macrophage
2
E-MEXP-1371, E-GEOD-2585
pachytene spermatocyte
2
E-GEOD-4193, E-TABM-412
conventional dendritic cell
1
E-GEOD-3691
thymic tumor
1
E-GEOD-2501
54 more value(s).


Disease state

studied in E-GEOD-19004, E-GEOD-21927, E-GEOD-6461, E-GEOD-2514, E-GEOD-1623, ... (14 experiments)

Factor Value U/D Experiments
hyperplasia
1
E-MEXP-1296
hyperglycaemic, obese and insulin resistant
1
E-MEXP-893
growth suppression
1
E-MEXP-835
insulin resistant
1
E-MEXP-1755
breast carcinoma
1
1
E-GEOD-2528
control
1
E-GEOD-19004
13 more value(s).


Compound treatment

studied in E-GEOD-21711, E-TABM-903, E-GEOD-5041, E-GEOD-4671, E-TABM-310, ... (36 experiments)

Factor Value U/D Experiments
cardiotoxin
1
2
E-MEXP-703, E-GEOD-469, E-GEOD-5304
MACA
1
E-GEOD-18707
sodium pyruvate
1
E-GEOD-5497
control medium
1
E-GEOD-21711
zymosan
1
E-GEOD-6376
allergen
1
E-GEOD-483
50 more value(s).


Agent

studied in E-GEOD-32706

Factor Value U/D Experiments
control
1
E-GEOD-32706
fenofibrate
1
E-GEOD-32706
fish oil
1
E-GEOD-32706


Amount to core
studied in E-GEOD-18858

Biosource provider
studied in E-GEOD-14906

cell population
studied in E-GEOD-26086

Clinical info
studied in E-MEXP-1458, E-GEOD-2127

Clinical treatment
studied in E-GEOD-5500

Cohort
studied in E-GEOD-20524, E-GEOD-4356

Developmental stage
studied in E-GEOD-1026, E-GEOD-1867, E-GEOD-8191, E-GEOD-989, E-GEOD-1947, ... (28 experiments)

Disease staging
studied in E-GEOD-17112

dose or concentration
studied in E-GEOD-18858

Environmental stress
studied in E-GEOD-16661

Family history
studied in E-GEOD-19194

Fraction
studied in E-TABM-363

Genetic modification
studied in E-GEOD-16361, E-GEOD-16362, E-GEOD-6980

Genotype
studied in E-GEOD-7020, E-MEXP-1649, E-TABM-285, E-GEOD-19194, E-GEOD-1381, ... (58 experiments)

Growth condition
studied in E-GEOD-1867, E-GEOD-4739, E-MEXP-1755, E-GEOD-495

Histology
studied in E-GEOD-15904

in vivo treatment
studied in E-GEOD-18858

Infection
studied in E-MEXP-1190, E-GEOD-17049, E-GEOD-4324, E-MEXP-1717, E-GEOD-20302, ... (7 experiments)

infection duration (days)
studied in E-GEOD-20524

infection status
studied in E-GEOD-20524

Injury
studied in E-GEOD-1999, E-GEOD-5296

Irradiate
studied in E-GEOD-2084, E-GEOD-4066

Light
studied in E-TABM-285

Media
studied in E-MEXP-718

Observation
studied in E-GEOD-3594, E-GEOD-5296

Od260
studied in E-GEOD-18858

Organism
studied in E-MEXP-667

Phenotype
studied in E-GEOD-272, E-GEOD-2788, E-GEOD-2640

Protocol type
studied in E-GEOD-16192

Replicate
studied in E-GEOD-17112

Rna integrity number
studied in E-GEOD-18858

RNAi
studied in E-MEXP-1342

Route of exposure
studied in E-GEOD-18858

Sampling time point
studied in E-GEOD-4356

Sex
studied in E-GEOD-21048

Stimulus or stress
studied in E-GEOD-15902

Strain or line
studied in E-GEOD-21927, E-GEOD-19322, E-TABM-562, E-MTAB-76, E-TABM-285, ... (16 experiments)

t cell type
studied in E-GEOD-17580

Temperature
studied in E-GEOD-20645

Treatment
studied in E-GEOD-19401, E-MTAB-76, E-GEOD-21902, E-GEOD-18344, E-GEOD-21841, ... (9 experiments)

Treatment repeat
studied in E-GEOD-18858

Treatment time
studied in E-GEOD-18858, E-GEOD-4356

Units of amount
studied in E-GEOD-18858

units of treatment repeat
studied in E-GEOD-18858

vehicle for chemical
studied in E-GEOD-18858

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM