Nbn
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Mus musculus |
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Nbn is differentially expressed in 161 experiments: 75 organism parts: liver, hippocampus, ... (73 more);, 8 disease states: normal, 3-NP-induced neurodegeneration model of Huntington's disease, ... (6 more);, 37 cell types 16 cell lines 26 compound treatments and 30 other conditions. |
| Synonyms |
'Nbs1' |
| Orthologs |
NBN
(Gallus gallus)
Nbn
(Rattus norvegicus)
ENSCING00000002421
(Ciona intestinalis)
NBN
(Bos taurus)
NBN
(Homo sapiens)
nbs
(Drosophila melanogaster)
nbn
(Xenopus laevis)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003684, GO:0008283, GO:0008284, GO:0007049, GO:0007126, GO:0004003, GO:0042493, GO:0000077, GO:0005622, GO:0005515, GO:0047485, GO:0006915, GO:0005730, GO:0005694, GO:0005634, GO:0005657, GO:0030870, GO:0006974, GO:0000723, GO:0032508, GO:0000781, GO:0000784, GO:0006302, GO:0006281, GO:0007095, GO:0031954, GO:0042405, GO:0048145, GO:0050885, GO:0001701, GO:0045665, GO:0001832, GO:0031576, GO:0031575, GO:0033674, GO:0045190 |
| Gene Ontology Term |
chromosome, telomeric region, telomere maintenance, DNA damage checkpoint, protein binding, apoptosis, DNA repair, cell proliferation, damaged DNA binding, Mre11 complex, intracellular, meiosis, positive regulation of cell proliferation, protein N-terminus binding, replication fork, double-strand break repair, transcription factor binding, DNA duplex unwinding, nuclear chromosome, telomeric region, cell cycle, nucleus, ATP-dependent DNA helicase activity, response to drug, chromosome, response to DNA damage stimulus, nucleolus, nuclear inclusion body, regulation of fibroblast proliferation, in utero embryonic development, blastocyst growth, mitotic cell cycle G2/M transition DNA damage checkpoint, neuromuscular process controlling balance, negative regulation of neuron differentiation, G2/M transition checkpoint, isotype switching, positive regulation of kinase activity, positive regulation of protein autophosphorylation, mitotic cell cycle G1/S transition checkpoint |
| InterPro ID |
IPR016592, IPR000253, IPR013908 |
| InterPro Term |
Nibrin_met, FHA_dom, DNA-repair_Nbs1_C |
| Ensembl Family |
ENSFM00250000006409 |
| Ensembl Family Description |
NIBRIN NIJMEGEN BREAKAGE SYNDROME 1 |
| EMBL-Bank ID |
BC044773, AL807737, AF092840, BC055061, AK031933, CH466538, AB016988, AK134960, AF076687 |
| Entrez Gene ID |
27354 |
| MGI Symbol |
Nbn |
| MGI ID |
MGI:1351625 |
| RefSeq ID |
NM_013752 |
| Ensembl Gene ID |
ENSMUSG00000028224 |
| Ensembl Transcript ID |
ENSMUST00000149069, ENSMUST00000029879 |
| MGI Description |
nibrin |
| Design Element |
4923553, 5566382, 5420549, 4845861, 4534183, gnf1m13284_at, 5212438, 5562761, 103805_at, 4793673, 10503431, 5503023, 1448746_at, 4985548, 5450813, 4425521, 5395799, 5290562, 4936367, 5328089, 4376700, ENSMUST00000149069, ENSMUST00000029879, 4977323 |
| Search EB-eye |
ENSMUSG00000028224
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