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Jag1
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Mus musculus
Jag1 is differentially expressed in 206 experiments: 97 organism parts: liver, kidney, ... (95 more);, 14 disease states: normal, 3-NP-induced neurodegeneration model of Huntington's disease, ... (12 more);, 51 cell types 20 cell lines 38 compound treatments and 32 other conditions.
Synonyms 'Serrate-1', 'Headturner', 'Htu', 'Ozz'
Orthologs ENSCING00000004617 (Ciona intestinalis)   Jag1 (Rattus norvegicus)   JAG1 (Bos taurus)   JAG1 (Homo sapiens)   Q90819_CHICK (Gallus gallus)   Ser (Drosophila melanogaster)   jag1 (Xenopus laevis)   (Compare orthologs)
Gene Ontology Term plasma membrane, protein binding, morphogenesis of an epithelial sheet, regulation of cell proliferation, membrane, positive regulation of Notch signaling pathway, cell communication, multicellular organismal development, Notch binding, Notch signaling pathway, apical part of cell, integral to membrane, negative regulation of cell differentiation, calcium ion binding, organ morphogenesis, inner ear development, positive regulation of myeloid cell differentiation, negative regulation of neuron differentiation, response to muramyl dipeptide, negative regulation of fat cell differentiation, auditory receptor cell differentiation, distal tubule development, neuronal stem cell maintenance, loop of Henle development, negative regulation of stem cell differentiation
InterPro Term Notch_ligand_N, VWF_C, EGF_extracell, EGF, DSL, VWC_out, EGF_3, EGF-like, EGF-like_Ca-bd
Search EB-eye ENSMUSG00000027276
Show more properties
Experimental Factors
Organism part

studied in E-TABM-1039, E-GEOD-3822, E-MEXP-114, E-GEOD-1479, E-TABM-865, ... (46 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-21515, E-GEOD-19732, E-GEOD-1956, E-GEOD-10246, E-MEXP-1672, ... (8 experiments)

Factor Value U/D Experiments
N1E-115 Tcof1 overexpressed
1
E-GEOD-1956
Gsc-GFP-EB5
1
E-MEXP-1672
Swiss3
1
E-GEOD-19732
B117H
2
1
E-GEOD-2788
Swiss22
1
E-GEOD-19732
14M1.4
1
E-MEXP-2554
14 more value(s).


Cell type

studied in E-GEOD-19401, E-GEOD-7069, E-GEOD-2433, E-GEOD-5309, E-GEOD-21749, ... (22 experiments)

Factor Value U/D Experiments
microglia
1
E-GEOD-10246
CD45+
1
1
E-GEOD-2057
CD45-
1
1
E-GEOD-2057
laminin non-binding germ cell
1
E-GEOD-829
lung epithelial cells from tracheas of Gprc5a wild_type
1
E-GEOD-21309
outer root sheath
1
E-GEOD-3142
45 more value(s).


Disease state

studied in E-MEXP-1296, E-GEOD-21927, E-GEOD-6461, E-GEOD-21902, E-MEXP-1137, ... (9 experiments)

Factor Value U/D Experiments
normal
2
3
E-GEOD-3583, E-GEOD-6461, E-MEXP-1137, E-MEXP-1296, E-GEOD-21902 ... (5 experiments)
tumor
1
E-GEOD-21902
MMTV-Neu
1
1
E-GEOD-15904
4T1 tumor-bearing
1
1
E-GEOD-21927
healthy
1
E-GEOD-21927
multiple myeloma
1
E-GEOD-6980
8 more value(s).


Compound treatment

studied in E-GEOD-6085, E-TABM-903, E-GEOD-1301, E-GEOD-4671, E-TABM-310, ... (27 experiments)

Factor Value U/D Experiments
control
3
5
E-GEOD-21710, E-GEOD-4260, E-GEOD-6085, E-GEOD-4671, E-GEOD-7694, ... (8 experiments)
DMN
1
1
E-MEXP-2209
BaP
1
1
E-MEXP-2209
human chorionic gonadotrophin
1
E-GEOD-4260
lipopolysaccharide
1
E-GEOD-10246
Pam2CSK4
1
E-TABM-310
32 more value(s).


Amount to core

studied in E-GEOD-18858

Factor Value U/D Experiments
50
1
1
E-GEOD-18858
15
1
1
E-GEOD-18858


Cohort
studied in E-GEOD-20524

Developmental stage
studied in E-MEXP-2457, E-GEOD-5668, E-GEOD-4870, E-MEXP-1672, E-TABM-412, ... (17 experiments)

dose or concentration
studied in E-GEOD-18858

Family history
studied in E-GEOD-19194

Fraction
studied in E-TABM-363

Generation
studied in E-GEOD-6527

Genotype
studied in E-GEOD-19684, E-MEXP-939, E-MEXP-1649, E-GEOD-2746, E-MEXP-1587, ... (30 experiments)

Growth condition
studied in E-GEOD-495

Histology
studied in E-GEOD-15904

in vivo treatment
studied in E-GEOD-18858

Infection
studied in E-GEOD-17049, E-MEXP-1717, E-GEOD-20302, E-MEXP-1942, E-GEOD-2973 ... (5 experiments)

infection duration (days)
studied in E-GEOD-20524

infection status
studied in E-GEOD-20524

Injury
studied in E-GEOD-1999

Irradiate
studied in E-GEOD-4066

Light
studied in E-TABM-285

Media
studied in E-MEXP-718

Observation
studied in E-GEOD-5296

Organism
studied in E-MEXP-667

Phenotype
studied in E-GEOD-2788, E-GEOD-2640

Rna integrity number
studied in E-GEOD-18858

sample preservation
studied in E-GEOD-18858

Sex
studied in E-MEXP-1711

Stimulus or stress
studied in E-GEOD-15894, E-GEOD-15902

Strain or line
studied in E-GEOD-17936, E-TABM-671, E-GEOD-21515, E-GEOD-21278, E-MTAB-76, ... (11 experiments)

Transfect
studied in E-GEOD-6487

Treatment
studied in E-MTAB-76, E-GEOD-21902, E-GEOD-18344, E-TABM-717, E-GEOD-21841, ... (8 experiments)

Treatment repeat
studied in E-GEOD-18858

Treatment time
studied in E-GEOD-18858

Units of amount
studied in E-GEOD-18858

vehicle for chemical
studied in E-GEOD-18858

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM