Pdgfrb
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Mus musculus |
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Pdgfrb is differentially expressed in 247 experiments: 103 organism parts: liver, kidney, ... (101 more);, 15 disease states: normal, 3-NP-induced neurodegeneration model of Huntington's disease, ... (13 more);, 62 cell types 22 cell lines 47 compound treatments and 35 other conditions. |
| Synonyms |
'CD140b', 'Pdgfr' |
| Orthologs |
PDGFRB
(Homo sapiens)
F1N868_CHICK
(Gallus gallus)
F1MBP1_BOVIN
(Bos taurus)
Pdgfrb
(Rattus norvegicus)
Pvr
(Drosophila melanogaster)
PDGFRB
(Xenopus laevis)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR007110, IPR009134, IPR013151, IPR020635, IPR003598, IPR003599, IPR016243, IPR013098 |
| Gene Ontology Term |
plasma membrane, phosphorylation, protein binding, cytoplasm, positive regulation of cell proliferation, membrane, peptidyl-tyrosine phosphorylation, protein tyrosine kinase activity, transforming growth factor beta receptor signaling pathway, receptor binding, positive regulation of MAP kinase activity, transmembrane receptor protein tyrosine kinase signaling pathway, glycosaminoglycan biosynthetic process, signal transducer activity, hemopoiesis, ATP binding, transferase activity, transferring phosphorus-containing groups, integral to plasma membrane, nucleus, receptor activity, nucleotide binding, kinase activity, protein serine/threonine kinase activity, transmembrane receptor protein tyrosine kinase activity, apical plasma membrane, transferase activity, integral to membrane, tissue homeostasis, regulation of actin cytoskeleton organization, nitrogen compound metabolic process, signal transduction, protein kinase activity, intracellular protein kinase cascade, cell chemotaxis, positive regulation of smooth muscle cell migration, in utero embryonic development, regulation of peptidyl-tyrosine phosphorylation, platelet-derived growth factor beta-receptor activity, kidney development, positive regulation of ERK1 and ERK2 cascade, positive regulation of collagen biosynthetic process, adrenal gland development, platelet-derived growth factor receptor signaling pathway, positive regulation of cell migration, positive regulation of anti-apoptosis, cardiac myofibril assembly, positive regulation of chemotaxis, smooth muscle tissue development, growth factor binding, platelet-derived growth factor binding, skeletal system morphogenesis, positive regulation of smooth muscle cell proliferation, vascular endothelial growth factor receptor signaling pathway, platelet-derived growth factor receptor binding, positive regulation of mitosis, protein autophosphorylation, protein phosphorylation, retina vasculature development in camera-type eye, positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway, metanephric glomerular mesangial cell proliferation involved in metanephros development, platelet-derived growth factor receptor-beta signaling pathway, cardiac vascular smooth muscle cell differentiation, positive regulation of reactive oxygen species metabolic process, metanephric glomerular capillary formation, positive regulation of calcium ion import, phosphatidylinositol 3-kinase binding, positive regulation of phosphatidylinositol 3-kinase cascade, positive regulation of DNA biosynthetic process, aorta morphogenesis, smooth muscle cell chemotaxis, metanephric mesenchymal cell migration, vascular endothelial growth factor-activated receptor activity, platelet-derived growth factor-activated receptor activity |
| Gene Ontology ID |
GO:0008284, GO:0016020, GO:0016021, GO:0007179, GO:0007169, GO:0007165, GO:0007243, GO:0016310, GO:0016301, GO:0016324, GO:0016740, GO:0016772, GO:0004713, GO:0004714, GO:0005524, GO:0005515, GO:0004871, GO:0004872, GO:0005737, GO:0005634, GO:0005886, GO:0005887, GO:0004672, GO:0004674, GO:0005102, GO:0006807, GO:0006468, GO:0000166, GO:0018108, GO:0046777, GO:0032956, GO:0001894, GO:0043548, GO:0006024, GO:0043406, GO:0030097, GO:0048008, GO:0048010, GO:0060326, GO:0048705, GO:0048745, GO:0048661, GO:0048407, GO:0014068, GO:0005161, GO:0055003, GO:0005019, GO:0005017, GO:0005021, GO:0050730, GO:0019838, GO:0045768, GO:0001701, GO:0032967, GO:0001822, GO:0014911, GO:0045840, GO:0030335, GO:0030325, GO:0070374, GO:0050921, GO:2000573, GO:0035791, GO:0035793, GO:0072262, GO:0072277, GO:0060947, GO:0061298, GO:0090280, GO:2000379, GO:0071670, GO:0035909, GO:0035789 |
| InterPro Term |
Ig_sub, Immunoglobulin, Prot_kinase_cat_dom, Ig-like, Ig_sub2, Ig_I-set, Tyr_kinase_VEGFR_rcpt_N, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Tyr_kinase_CSF1/PDGF_rcpt, Se/Thr_kinase-like_dom |
| Ensembl Family |
ENSFM00440000236844 |
| Ensembl Family Description |
FACTOR RECEPTOR PRECURSOR EC_2.7.10.1 |
| RefSeq ID |
NM_008809, NM_001146268 |
| Ensembl Gene ID |
ENSMUSG00000024620 |
| MGI ID |
MGI:97531 |
| Entrez Gene ID |
18596 |
| MGI Symbol |
Pdgfrb |
| MGI Description |
platelet derived growth factor receptor, beta polypeptide |
| Ensembl Transcript ID |
ENSMUST00000025522, ENSMUST00000115274 |
| EMBL-Bank ID |
AC124448 |
| Design Element |
4883874, 5027184, 4325582, 4948226, 4331044, mm_Pdgfrb, 4997438, 5522556, gnf1m01562_a_at, 1417148_at, X04367_s_at, 5137100, 4545940, 4354622, 1436970_a_at, 5012864, 5148116, 4666288, 4780002, 4380549, 4365048, 10456046, 4969679, 4722440, 160867_at, 4497207, 5581077, 4403670, 4462063, 4603547, 4974418, 5498327, 4924307, 5092665, 4808796, 4629715, 5538473, 5013780, ENSMUST00000115274, 5233868, ENSMUST00000025522 |
| Search EB-eye |
ENSMUSG00000024620
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