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Sfpi1
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Mus musculus
Sfpi1 is differentially expressed in 186 experiments: 76 organism parts: liver, spleen, ... (74 more);, 11 disease states: normal, 4T1 tumor-bearing, ... (9 more);, 38 cell types 6 cell lines 25 compound treatments and 25 other conditions.
Synonyms 'PU.1', 'Dis-1', 'Tcfpu1', 'Sfpi-1', 'Spi-1', 'Tfpu.1'
Orthologs SPI1 (Homo sapiens)   E1BJR2_BOVIN (Bos taurus)   E1BZN0_CHICK (Gallus gallus)   Spi1 (Rattus norvegicus)   spi1 (Xenopus laevis)   (Compare orthologs)
Gene Ontology Term DNA binding, protein binding, regulation of transcription, DNA-dependent, nuclear chromatin, transcription, DNA-dependent, sequence-specific DNA binding, induction of apoptosis, nucleus, somatic stem cell maintenance, transcription factor complex, regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, RNA binding, myeloid leukocyte differentiation, negative regulation of MHC class II biosynthetic process, regulation of erythrocyte differentiation, granulocyte differentiation, erythrocyte differentiation, lymphocyte differentiation, lymphoid progenitor cell differentiation, vasculature development, anatomical structure regression, myeloid dendritic cell differentiation, macrophage differentiation, sequence-specific DNA binding transcription factor activity, RNA polymerase II transcription factor binding
InterPro Term Ets
Search EB-eye ENSMUSG00000002111
Show more properties
Experimental Factors
Organism part

studied in E-TABM-1039, E-GEOD-3963, E-GEOD-2161, E-GEOD-2866, E-MEXP-565, ... (50 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-21515, E-GEOD-10246, E-MEXP-2554, E-GEOD-2788, E-GEOD-11259 ... (5 experiments)

Factor Value U/D Experiments
B140P
1
1
E-GEOD-2788
RAW264.7
1
E-GEOD-10246
IP36D-3
1
E-GEOD-21515
4T1
1
E-GEOD-11259
MBA1
1
E-MEXP-2554
RAW264
1
E-MEXP-2554


Cell type

studied in E-GEOD-2585, E-GEOD-7764, E-GEOD-2433, E-GEOD-21749, E-TABM-130, ... (16 experiments)

Factor Value U/D Experiments
hematopoietic stem cell
3
E-MEXP-1158, E-GEOD-20377, E-MEXP-2072
macrophage
2
E-MEXP-1371, E-GEOD-2585
T-reg_control-treated
1
E-GEOD-1419
memory B cell
1
E-GEOD-4142
resting natural killer cell
1
E-GEOD-7764
germinal center B cell
1
E-GEOD-4142
32 more value(s).


Disease state

studied in E-MEXP-1296, E-GEOD-21927, E-GEOD-21902, E-GEOD-2952, E-GEOD-1871, ... (7 experiments)

Factor Value U/D Experiments
4T1 tumor-bearing
1
E-GEOD-21927
tumor
1
E-GEOD-21902
prostate carcinoma
1
E-MEXP-1296
myocardial infarction
1
E-GEOD-775
sham
1
E-GEOD-775
LPS-induced acute lung injury
1
E-GEOD-1871
5 more value(s).


Compound treatment

studied in E-GEOD-21711, E-GEOD-19684, E-GEOD-1301, E-GEOD-469, E-MEXP-1814, ... (21 experiments)

Factor Value U/D Experiments
cardiotoxin
3
E-GEOD-5304, E-GEOD-469, E-MEXP-703
lipopolysaccharide
1
2
E-GEOD-10246, E-GEOD-2411, E-TABM-310
doxycycline
1
E-MEXP-1702
IGF-1
1
E-GEOD-17140
Fenofibrate
1
E-MEXP-3282
control medium
1
E-GEOD-21711
19 more value(s).


Amount to core

studied in E-GEOD-18858

Factor Value U/D Experiments
50
1
E-GEOD-18858


cell population
studied in E-GEOD-26086

Clinical info
studied in E-MEXP-1458

Clinical treatment
studied in E-TABM-195

Developmental stage
studied in E-GEOD-5668, E-MEXP-1853, E-GEOD-5306, E-GEOD-5831, E-TABM-412, ... (14 experiments)

dose or concentration
studied in E-GEOD-18858

Genotype
studied in E-GEOD-1026, E-GEOD-19684, E-GEOD-7020, E-MEXP-1649, E-GEOD-2746, ... (34 experiments)

Histology
studied in E-GEOD-15904

in vivo treatment
studied in E-GEOD-18858

Individual
studied in E-GEOD-18858

Infection
studied in E-MEXP-1190, E-GEOD-17049, E-MEXP-1717, E-GEOD-20302, E-MEXP-1942, ... (7 experiments)

infection duration (days)
studied in E-GEOD-20524

infection status
studied in E-GEOD-20524

Injury
studied in E-GEOD-2392, E-GEOD-5296

Irradiate
studied in E-GEOD-4066

Light
studied in E-TABM-285

Observation
studied in E-GEOD-3594, E-GEOD-5296

Od260
studied in E-GEOD-18858

Organism
studied in E-MEXP-667

Phenotype
studied in E-GEOD-272, E-GEOD-15840, E-GEOD-2640

Protocol type
studied in E-GEOD-2917

Rna integrity number
studied in E-GEOD-18858

Sex
studied in E-MEXP-1711

Strain or line
studied in E-GEOD-17936, E-GEOD-21927, E-TABM-671, E-GEOD-16994, E-MTAB-76, ... (7 experiments)

Treatment
studied in E-MTAB-76, E-GEOD-21902, E-GEOD-18344, E-GEOD-22009, E-GEOD-21841, ... (9 experiments)

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM