LTA
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Homo sapiens |
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LTA is differentially expressed in 181 experiments: 59 organism parts: blood, tonsil, ... (57 more);, 126 disease states: normal, lung adenocarcinoma, ... (124 more);, 59 cell types 214 cell lines 30 compound treatments and 71 other conditions. |
| Synonyms |
LT, TNFB, TNFSF1 |
| Orthologs |
tnfb
(Danio rerio)
tnfa
(Danio rerio)
TNFB_BOVIN
(Bos taurus)
Lta
(Mus musculus)
Lta
(Rattus norvegicus)
NP_001107150.1
(Xenopus laevis)
TNFB_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
humoral immune response, extracellular space, membrane, tumor necrosis factor receptor binding, extracellular region, receptor binding, cell-cell signaling, response to hypoxia, cytokine activity, positive regulation of apoptosis, defense response to Gram-positive bacterium, response to nutrient, induction of apoptosis, response to lipopolysaccharide, immune response, response to drug, signal transduction, negative regulation of fibroblast proliferation, positive regulation of chronic inflammatory response to antigenic stimulus, positive regulation of humoral immune response mediated by circulating immunoglobulin, lymph node development, positive regulation of interferon-gamma production, negative regulation of growth of symbiont in host |
| Gene Ontology ID |
GO:0016020, GO:0007165, GO:0007267, GO:0007584, GO:0042493, GO:0005615, GO:0005576, GO:0006917, GO:0006959, GO:0006955, GO:0005102, GO:0005125, GO:0032496, GO:0005164, GO:0043065, GO:0050830, GO:0001666, GO:0002876, GO:0048535, GO:0048147, GO:0032729, GO:0044130, GO:0002925 |
| InterPro ID |
IPR006052, IPR002960, IPR006053 |
| InterPro Term |
TNF_family, TNF_beta, TNF_a/b/c |
| Ensembl Family Description |
LYMPHOTOXIN ALPHA PRECURSOR LT ALPHA TNF BETA TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 1 |
| Ensembl Family |
ENSFM00500000272273 |
| EMBL-Bank ID |
D00102, M55913, BX927320, AL662801, AY216498, EU338451, X01393, AB088112, BA000025, AY070490, CH471081, BC034729, AB103618, D12614, Z15026, X02911, BX248519, M16441, Y14768, DQ123821, AY274923, AY274922, AY274919, AY274915, AY274906, AY274908, AF129756 |
| Gene-Disease Assocation |
PSORIATIC ARTHRITIS, SUSCEPTIBILITY TO, LEPROSY, SUSCEPTIBILITY TO, 4; LPRS4 |
| Ensembl Protein ID |
ENSP00000403495, ENSP00000404769, ENSP00000413450 |
| UniGene ID |
Hs.36 |
| Description |
lymphotoxin alpha (TNF superfamily, member 1) [Source:HGNC Symbol;Acc:6709] |
| Entrez Gene ID |
4049 |
| UniProt Accession |
Q6WQV6, P01374, Q5STV3, Q45NE9, E7ET53 |
| RefSeq ID |
NP_001153212, NP_000586, NM_000595, NM_001159740 |
| Ensembl Gene ID |
ENSG00000226979 |
| HGNC Symbol |
LTA |
| Ensembl Transcript ID |
ENST00000454783, ENST00000436827, ENST00000471842, ENST00000418386, ENST00000489638 |
| Design Element |
ENST00000471842, 206975_at, 36296_at, ENST00000436827, M16441_cds1_at, g6806892_3p_at, 258_at, ENST00000418386, ENST00000489638, ENST00000454783 |
| Search EB-eye |
ENSG00000226979
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