NRAS
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Homo sapiens |
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NRAS is differentially expressed in 286 experiments: 100 organism parts: mammary gland, tonsil, ... (98 more);, 145 disease states: normal, glioblastoma, ... (143 more);, 93 cell types 363 cell lines 23 compound treatments and 71 other conditions. |
| Synonyms |
N-ras |
| Orthologs |
RAS2
(Saccharomyces cerevisiae)
nras
(Danio rerio)
RASN_CHICK
(Gallus gallus)
Nras
(Mus musculus)
RAS1
(Saccharomyces cerevisiae)
Nras
(Rattus norvegicus)
Ras85D
(Drosophila melanogaster)
nras
(Xenopus laevis)
A5D7R9_BOVIN
(Bos taurus)
O62639_CANFA
(Canis familiaris)
(Compare orthologs)
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| Ensembl Family Description |
RAS PRECURSOR |
| Gene Ontology Term |
plasma membrane, GTPase activity, protein binding, visual learning, epidermal growth factor receptor signaling pathway, intracellular, positive regulation of cell proliferation, membrane, Golgi membrane, Golgi apparatus, MAPKKK cascade, insulin receptor signaling pathway, blood coagulation, membrane fraction, GTP catabolic process, GTP binding, activation of MAPKK activity, actin cytoskeleton organization, Ras protein signal transduction, axon guidance, small GTPase mediated signal transduction, nucleotide binding, signal transduction, protein transport, negative regulation of neuron apoptosis, striated muscle cell differentiation, regulation of long-term neuronal synaptic plasticity, leukocyte migration, positive regulation of Rac protein signal transduction, regulation of synaptic transmission, GABAergic, nerve growth factor receptor signaling pathway, Ral guanyl-nucleotide exchange factor activity |
| Gene Ontology ID |
GO:0008286, GO:0008284, GO:0016020, GO:0015031, GO:0003924, GO:0007173, GO:0007165, GO:0007264, GO:0007265, GO:0008542, GO:0007411, GO:0007596, GO:0005622, GO:0005624, GO:0005525, GO:0005515, GO:0005886, GO:0005794, GO:0000165, GO:0000166, GO:0000186, GO:0000139, GO:0043524, GO:0006184, GO:0030036, GO:0048011, GO:0008321, GO:0051146, GO:0048169, GO:0050900, GO:0035022, GO:0032228 |
| InterPro ID |
IPR000795, IPR006689, IPR005225, IPR001806, IPR013684, IPR003578, IPR003579, IPR020849 |
| InterPro Term |
MIRO-like, ProtSyn_GTP-bd, Small_GTPase, Small_GTP-bd_dom, Small_GTPase_ARF/SAR, Small_GTPase_Ras, Small_GTPase_Rho, Small_GTPase_Rab_type |
| Ensembl Family |
ENSFM00500000269718 |
| Description |
neuroblastoma RAS viral (v-ras) oncogene homolog [Source:HGNC Symbol;Acc:7989] |
| UniProt Accession |
Q5U091, Q9UM97, Q71SP6, P01111, P78460, E5FF39 |
| UniGene ID |
Hs.615805, Hs.486502 |
| EMBL-Bank ID |
AF285779, X05565, AY428630, M10055, M19990, X00642, X00643, X00644, X00645, L00041, L00040, L00043, L00042, BT019734, BT019735, AL096773, S68580, X53292, X53291, AF493919, EU332857, CH471122, K03211, X02751, X07440, BC005219, M25898, EF685661, EF685662, HM459605 |
| Entrez Gene ID |
4893 |
| HGNC Symbol |
NRAS |
| Ensembl Protein ID |
ENSP00000358548 |
| RefSeq ID |
NP_002515, NM_002524 |
| Ensembl Gene ID |
ENSG00000213281 |
| Gene-Disease Assocation |
THYROID CARCINOMA, FOLLICULAR; FTC, NOONAN SYNDROME 6; NS6, COLORECTAL CANCER; CRC, JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML |
| Ensembl Transcript ID |
ENST00000369535 |
| Design Element |
g6006027_3p_a_at, ENST00000369535, Hs.260523.1.A1_3p_at, 202647_s_at, 224985_at, X02751_at, 1539_at |
| Search EB-eye |
ENSG00000213281
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