NTRK1
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Homo sapiens |
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NTRK1 is differentially expressed in 148 experiments: 62 organism parts: kidney, blood, ... (60 more);, 105 disease states: normal, chronic myelogenous leukemia, ... (103 more);, 43 cell types 126 cell lines 20 compound treatments and 66 other conditions. |
| Synonyms |
MTC, TRKA, TRK |
| Orthologs |
F1MC14_BOVIN
(Bos taurus)
Ntrk1
(Rattus norvegicus)
Ntrk1
(Mus musculus)
ntrk1
(Danio rerio)
NTRK1
(Gallus gallus)
sev
(Drosophila melanogaster)
ntrk1
(Xenopus laevis)
NTRK1
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR000483, IPR007110, IPR020635, IPR020777, IPR020461 |
| Gene Ontology ID |
GO:0048015, GO:0009986, GO:0016020, GO:0007169, GO:0007190, GO:0007264, GO:0007265, GO:0007275, GO:0007202, GO:0007399, GO:0004713, GO:0004714, GO:0005524, GO:0005515, GO:0004872, GO:0005737, GO:0005886, GO:0005887, GO:0005768, GO:0004672, GO:0004674, GO:0006468, GO:0000166, GO:0000186, GO:0000139, GO:0046777, GO:0043524, GO:0030154, GO:0048011, GO:0042490, GO:0005030, GO:0043121, GO:0030183, GO:0071363 |
| Gene Ontology Term |
plasma membrane, protein binding, cytoplasm, membrane, Golgi membrane, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase signaling pathway, cell differentiation, activation of MAPKK activity, ATP binding, Ras protein signal transduction, small GTPase mediated signal transduction, multicellular organismal development, integral to plasma membrane, activation of phospholipase C activity, receptor activity, nucleotide binding, endosome, protein serine/threonine kinase activity, transmembrane receptor protein tyrosine kinase activity, nervous system development, cell surface, protein kinase activity, activation of adenylate cyclase activity, negative regulation of neuron apoptosis, neurotrophin binding, B cell differentiation, cellular response to growth factor stimulus, mechanoreceptor differentiation, neurotrophin receptor activity, nerve growth factor receptor signaling pathway, protein autophosphorylation, protein phosphorylation, phosphatidylinositol-mediated signaling |
| InterPro Term |
Cys-rich_flank_reg_C, Prot_kinase_cat_dom, Ig-like, Tyr_kinase_neurotrophic_rcpt_1, Tyr_kinase_NGF_rcpt, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Ensembl Family |
ENSFM00260000050374 |
| Ensembl Family Description |
3 GROWTH RECEPTOR PRECURSOR EC_2.7.10.1 GP145 TRK NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE TYROSINE KINASE |
| Description |
neurotrophic tyrosine kinase, receptor, type 1 [Source:HGNC Symbol;Acc:8031] |
| RefSeq ID |
NM_001012331, NM_001007792, NP_001007793, NP_002520, NP_001012331, NM_002529 |
| EMBL-Bank ID |
X62947, X03541, X06704, AL158169, AB019488, AK312704, BC144239, M23102, BC136554, X85960, AY321513, BC062580 |
| Entrez Gene ID |
4914 |
| HGNC Symbol |
NTRK1 |
| Ensembl Protein ID |
ENSP00000357179, ENSP00000351486, ENSP00000376120, ENSP00000431418, ENSP00000436804 |
| Gene-Disease Assocation |
THYROID CARCINOMA, PAPILLARY, INSENSITIVITY TO PAIN, CONGENITAL, WITH ANHIDROSIS; CIPA, THYROID CARCINOMA, FAMILIAL MEDULLARY; MTC |
| UniProt Accession |
P04629, A6NF12, E9PQG0 |
| Ensembl Gene ID |
ENSG00000198400 |
| Ensembl Transcript ID |
ENST00000530298, ENST00000524377, ENST00000358660, ENST00000497019, ENST00000534682, ENST00000392302, ENST00000531606, ENST00000368196, ENST00000533630, ENST00000489021 |
| UniGene ID |
Hs.406293 |
| Design Element |
ENST00000392302, ENST00000489021, g4585711_3p_a_at, ENST00000531606, ENST00000533630, 208605_s_at, 1892_s_at, 36805_s_at, ENST00000530298, ENST00000534682, ENST00000358660, ENST00000368196, ENST00000524377, ENST00000497019 |
| Search EB-eye |
ENSG00000198400
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