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PSAP Homo sapiens
PSAP is differentially expressed in 128 experiments [140 up/147 dn]: 23 organism parts: peripheral blood [2 up/0 dn], skeletal muscle [0 up/2 dn], ...; 37 disease states: normal [6 up/10 dn], breast carcinoma [2 up/0 dn], ...; 38 cell types, 34 cell lines, 25 compound treatments and 20 other conditions.
Synonyms GLBA, PSAP, RP11-472K8.1-001, hCG_1787837, SAP1
Orthologs psap (Danio rerio)  SAP_RAT (Rattus norvegicus)  Psap (Mus musculus)  (Compare orthologs)
InterPro Term Saposin, Saposin B, Saposin type A, Saposin-like type B, 1, Saposin-like type B, 2
Diseases Combined SAP deficiency, Gaucher disease, atypical, Krabbe disease, atypical, Metachromatic leukodystrophy due to SAP-b deficiency
GO Terms Golgi apparatus, enzyme activator activity, extracellular space, integral to membrane, lipid transport
Uniprot P07602  Q53FJ5  Q53Y86  Q5BJH1  Q59EN5 
Search EB-eye ENSG00000197746
REST API
Expression Summary
236 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
10
6
None Compound treatment
3
2
Homo sapiens Organism
3
Organism_part Material type
1
2
Cell Material type
2
1
Monocyte Cell type
2
N/a Test result
2
CD34+ Cell type
2
Breast carcinoma Disease state
2
Not applicable Histology
2
FLAP Compound treatment
2
Invasive ductal carcinoma Histology
2
MK886 Compound treatment
2
Fibroblast Cell type
2
Caco-2 Cell line
2
Peripheral blood Organism part
2
Macaca mulatta Organism
2
0 cm away from the tumor bound... Observation
2
Cystic change Histology
2
HNRPA2B Compound treatment
2
Acute myeloid leukemia Disease state
2
Skeletal muscle Organism part
2
Umbilical cord Organism part
1
1
Adult Developmental stage
1
1
Dimethyl sulfoxide Compound treatment
1
1
CD14+ monocyte Cell type
2
Pan troglodytes Organism
1
1
Primary Disease staging
1
1
Chronic lymphocytic leukemia Disease state
1
1
Bone marrow Organism part
1
1
Acute promyelocytic leukemia Disease state
1
1
SKMEL5 Cell line
1
SW480 Cell line
1
SW620 Cell line
1
SKBR3 Cell line
1
Blood Organism part
1
Fetus Developmental stage
1
Cerebellum Organism part
1
Caudate nucleus Organism part
1
Plasma cell Cell type
1
B lymphocyte Cell type
1
Acute radiation toxicity Clinical history
1
T47D Cell line
1
Pretreatment primary sample Clinical info
1
Fetal bovine serum in media Growth condition
1
Glucocorticoid resistant Phenotype
1
Multiple myeloma Disease state
1
Enzo Labeling Protocol type
1
Glucocorticoid sensitive Phenotype
1
Malignant melanoma Disease state
1
Bacterial endotoxin Compound treatment
1
Control Compound treatment
1
ITS medium Growth condition
1
ITS medium with albumin-bound ... Growth condition
1
Postprandial lipid micelles in... Growth condition
1
Inter-prandial lipid micelles ... Growth condition
1
X-linked chronic granulomatous Disease state
1
MDA-MB-231 Cell line
1
T cell Cell type
1
Peripheral blood mononuclear c... Cell type
1
Baseline uninfected Disease state
1
U937 Cell line
1
Affymetrix Labeling Protocol type
1
Chondrocyte Cell type
1
MCF7 Cell line
1
Geriatric Developmental stage
1
Pediatric Developmental stage
1
Vascular smooth muscle cell Cell type
1
Tumor Organism part
1
Endometrioid carcinoma Disease state
1
GLI56 Cell line
1
Serum starvation synchronizati... Growth condition
1
Rapamycin Compound treatment
1
Benign nevi Disease state
1
Endothelial cell Cell type
1
T84 Cell line
1
GLI72 Cell line
1
Capra hircus Organism
1
Johnsen score count 2: Sertoli... Histology
1
CD3+ CD4+ CD8- CD45RA+ CD62L+ Phenotype
1
Naive T cell Cell type
1
Kidney Organism part
1
Primary gastric tumor Organism part
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
PC3 Cell line
1
Stage I Disease staging
1
Spermatocyte Cell type
1
Epidermal keratinocyte Cell type
1
SkinEthic keratinocyte Cell type
1
CodeLink Labeling Protocol type
1
Limited radiation toxicity Clinical history
1
Carcinoma in situ lesion Disease state
1
YCC16 Cell line
1
Lymphatic endothelial cell Cell type
1
MDA468 Cell line
1
Lipopolysaccharide Compound treatment
1
Circulating neutrophil Cell type
1
HaCaT Cell line
1
Differentiated Cell type
1
Naive Cell type
1
Native skin Cell type
1
HTERT/HPVE6/HPVE7/SV40t/hRas t... Gene modification
1
Superficial transitional cell ... Disease state
1
Unsynchronized Growth condition
1
Stage II Disease staging
1
YCC1 Cell line
1
Atrial mycocardium Organism part
1
Ventricular myocardium Organism part
1
Placebo Compound treatment
1
CD16+ dendritic cell Cell type
1
Seminiferous tubule Organism part
1
MCF10A Cell line
1
CD3- CD4+ CD8- Phenotype
1
Intrathymic T progenitor cell Cell type
1
White blood cells Organism part
1
T3aNxM1 Disease staging
1
Hypericin incubated, not irrad... Growth condition
1
Hypericin incubated, irradiate... Growth condition
1
Testis Organism part
1
HTERT/HPVE6/HPVE7/SV40t transf... Gene modification
1
Cartilage Organism part
1
Alveolar space neutrophil Cell type
1
Metastatic Disease staging
1
Infant Developmental stage
1
CD3int CD4+ CD8+ Phenotype
1
Double positive thymocyte Cell type
1
Primary culture 1 Cell line
1
HTERT/HPVE6 transfection Gene modification
1
Lymph node Organism part
1
Tonsil Organism part
1
NCI-H929 Cell line
1
HL-60 Cell line
1
Acute malaria, natural infecti... Disease state
1
Heregulin Compound treatment
1
CD3high CD4+ CD8- Phenotype
1
Single positive thymocyte Cell type
1
Adipose-derived stem cell Cell type
1
BDCA3+ dendritic cell Cell type
1
TIVE Cell line
1
293 Cell line
1
5-aza-2'-deoxycytidine + trich... Compound treatment
1
Heat-killed HL60 cell lysate Infection
1
HMEC184 Cell line
1
Nickel(II) chloride hexahydrat... Compound treatment
1
2-(3,4,5-trimethoxy-phenylamin... Compound treatment
1
Stromal cell Cell type
1
Muscle invasive carcinoma Disease state
1
Arsenic oxide Compound treatment
1
Primary culture 2 Cell line
1
Methotrexate Compound treatment
1
2,3-dimethoxy-1,4-naphthoquino... Compound treatment
1
CD8+ T cell Cell type
1
Experimental malaria-infected Disease state
1
BCKN-1 Cell line
1
Vasectomized Clinical history
1
CD19+ B cells (neg. sel.) Cell type
1
Johnsen score count 5: no sper... Histology
1
Stroma from endometriotic nodu... Organism part
1
Granulocyte Cell type
1
HTERT transfection Gene modification
1
GLI60 Cell line
1
AdERb high moi Gene modification
1
Idiopathic dilated cardiomyopa... Disease state
1
HMT3522S1 Cell line
1
Hydroxyurea Compound treatment
1
MDS-associated acute myeloid l... Disease state
1
Testicular seminoma Disease state
1
Respiratory syncytial virus Infection
1
Spermatid Cell type
1
Astrocytic tumor Disease state
1
Estrogen receptor 1 negative; ... Test result
1
Sham surgery Clinical treatment
1
IgV mutated Genotype
1
CD11c+ dendritic cell Cell type
1
G3 Tumor grading
1
CD19+ B-cell Cell type
1
Macrophage Cell type
1
Drug-naive Clinical treatment
1
ERalpha transfected Genotype
1
ERbeta transfected Genotype
1
B-precursor acute lymphoblasti... Disease state
1
1,10-phenanthroline Compound treatment
1
Lymph node metastasis Disease staging
1
Control RNAi
1
SIM2s RNAi
1
Johnsen score count 3.2: Serto... Histology
1
CXCR5(-)ICOS(-/lo) CD4 T cell Target cell type
1
Cadmium chloride 2.5-hydrate Compound treatment
1
Proliferative Developmental stage
1
Differentiated Developmental stage
1
CD4+ T-cell Cell type
1
CD105+ endothelial Cell type
1
HPL1 Cell line
1
Control Clinical history
1
Johnsen score count 10: full s... Histology
1
BT474 Cell line
1
Breast cancer Disease state
1
Plasma cell leukemia Disease state
1
T2N0M0 Disease staging
1
Ewing family tumor Disease state
1
Neuroblastoma Disease state
1
Kaposi's sarcoma Disease state
1
U266 Cell line
1
Bis [(+)-tartrato] diantimonat... Compound treatment
1
Salivary gland Organism part
1
Dermatomyositis Disease state
1
Pancreas Organism part
1
Daudi Burkitt's lymphoma Disease state
1
Monoclonal gammopathy of undet... Disease state
1
Congestive cardiomyopathy Disease state
1
Control - keratinocyte growth ... Compound treatment
1
Pancreatic cancer Disease state
1
N-nitrosodimethylamine Compound treatment
1
17-allylamino-geldanamycin Compound treatment
1
Selenium Compound treatment
1
Cervical cancer Disease state
1
IMP(1,3)A RNAi
1
Uterine cervix Organism part
1
Prostate Organism part
1
Estrogen receptor 1 positive; ... Test result
1
SCH Cell line
1
Female Sex
1
Asynchronous Growth condition
1
Papillary thyroid carcinoma Disease state
1
Grade II Tumor grading
1
Uninfected Infection
1
T47-D Cell line
1
Pulmonary arterial hypertensio... Disease state
1
HIV-1 seropositive Disease state
1
YCC10 Cell line
1
Unknown_sex Sex
1
Skin substitute Cell type
1
Diagnosed with skin cancer bef... Clinical history
1
Empty adenovirus Gene modification
1
Lin- CD34- Phenotype
1
Expression Profiles
E-GEOD-5258: Transcription profiling of human cell lines freely cycling treated with 164 distinct small molecules - Broad Connectivity Map CMAP Set 1
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-1725: Transcription profiling of human lymphoblastoid cells from patients with limited or acute radiation toxicity, skin cancer patients and normal controls, exposed to UV or IR light
Experimental Factors
Individual Light Clinical history
Show expression profile  /  experiment details

 
E-MEXP-1014: Transcription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-4646: Transcription profiling of human HUVEC cells infected with Neisseria meningitidis wild type and mutants vs uninfected sampled at 3 time points
Experimental Factors
Time Infection
Show expression profile  /  experiment details

 
E-GEOD-5824: Transcription profiling of human Acute Lymphoblastic Leukemia CEM_C1 cells treated with rapamycin identifies rapamycin as a glucocorticoid resistance reversal agent
Experimental Factors
Phenotype Time Clinical info Dose Compound treatment
Show expression profile  /  experiment details

 
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