SRC
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Homo sapiens |
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SRC is differentially expressed in 271 experiments: 126 organism parts: liver, blood, ... (124 more);, 214 disease states: normal, acute lymphoblastic leukemia, ... (212 more);, 80 cell types 371 cell lines 40 compound treatments and 75 other conditions. |
| Synonyms |
c-src, ASV, SRC1 |
| Orthologs |
ENSCING00000003850
(Ciona intestinalis)
src
(Danio rerio)
SRC
(Bos taurus)
Src
(Rattus norvegicus)
SRC_CHICK
(Gallus gallus)
Src
(Mus musculus)
ENSCING00000008550
(Ciona intestinalis)
src
(Xenopus laevis)
SRC
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001452, IPR011511, IPR001245, IPR017442, IPR000719, IPR000980, IPR020635 |
| Gene Ontology Term |
oogenesis, cytosol, cell migration, plasma membrane, phosphorylation, protein binding, cellular membrane organization, SH2 domain binding, mitochondrial inner membrane, epidermal growth factor receptor signaling pathway, signal complex assembly, peptidyl-tyrosine phosphorylation, protein tyrosine kinase activity, receptor binding, blood coagulation, protein domain specific binding, heme binding, ephrin receptor binding, fibroblast growth factor receptor signaling pathway, ATP binding, Ras protein signal transduction, axon guidance, SH3/SH2 adaptor activity, nucleotide binding, kinase activity, protein serine/threonine kinase activity, integrin binding, non-membrane spanning protein tyrosine kinase activity, signal transduction, protein kinase activity, caveola, mitochondrion, intracellular protein kinase cascade, regulation of estrogen receptor signaling pathway, leukocyte migration, positive regulation of ERK1 and ERK2 cascade, regulation of vascular permeability, positive regulation of integrin activation, forebrain development, uterus development, positive regulation of canonical Wnt receptor signaling pathway, response to interleukin-1, interspecies interaction between organisms, regulation of bone resorption, branching involved in mammary gland duct morphogenesis, nerve growth factor receptor signaling pathway, bone resorption, T cell costimulation, platelet activation, protein phosphorylation, ion channel binding, cell junction assembly |
| InterPro Term |
SH2, SH3_domain, Prot_kinase_cat_dom, SH3_2, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Gene Ontology ID |
GO:0016044, GO:0007172, GO:0007173, GO:0007165, GO:0016477, GO:0007243, GO:0007265, GO:0016310, GO:0016301, GO:0008543, GO:0007411, GO:0005901, GO:0007596, GO:0048477, GO:0004713, GO:0004715, GO:0005524, GO:0005515, GO:0005739, GO:0005743, GO:0005886, GO:0005829, GO:0004672, GO:0004674, GO:0005102, GO:0005178, GO:0005070, GO:0019904, GO:0006468, GO:0000166, GO:0018108, GO:0046875, GO:0042169, GO:0020037, GO:0048011, GO:0060444, GO:0060065, GO:0030900, GO:0031295, GO:0043114, GO:0044419, GO:0070555, GO:0030168, GO:0033625, GO:0045124, GO:0045453, GO:0070374, GO:0050900, GO:0033146, GO:0090263, GO:0044325, GO:0034329 |
| Ensembl Family Description |
TYROSINE KINASE EC_2.7.10.2 |
| Ensembl Family |
ENSFM00250000000068 |
| Ensembl Protein ID |
ENSP00000350941, ENSP00000353950, ENSP00000408503, ENSP00000362659, ENSP00000362668, ENSP00000362680 |
| EMBL-Bank ID |
AL133293, BC051270, X03996, X03995, X03998, X03997, X03999, AF077754, AK024281, X04000, CH471077, K03212, K03213, K03214, K03215, K03216, K03217, K03218, X02647, M16237, M16244, M16243, M16245, BC011566 |
| HGNC Symbol |
SRC |
| RefSeq ID |
NM_005417, NM_198291, NP_938033, NP_005408 |
| UniProt Accession |
Q71UK5, Q9H7V3, P12931 |
| Description |
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) [Source:HGNC Symbol;Acc:11283] |
| Entrez Gene ID |
6714 |
| UniGene ID |
Hs.675407, Hs.195659, Hs.597733 |
| Ensembl Gene ID |
ENSG00000197122 |
| Ensembl Transcript ID |
ENST00000467556, ENST00000373558, ENST00000373567, ENST00000373578, ENST00000493775, ENST00000360723, ENST00000358208, ENST00000497734, ENST00000477066, ENST00000445403, ENST00000477475, ENST00000498178, ENST00000472968, ENST00000489153 |
| Design Element |
Hs2.383588.1.A1_3p_s_at, ENST00000472968, 1565082_x_at, ENST00000498178, ENST00000497734, 1938_at, 1565080_at, ENST00000477066, ENST00000360723, ENST00000373578, ENST00000467556, ENST00000373558, 213324_at, ENST00000477475, 1558211_s_at, 38904_at, ENST00000358208, ENST00000489153, Hs.198298.0.S1_3p_at, K03218_at, ENST00000445403, 221284_s_at, Hs2.383588.2.A1_3p_at, ENST00000373567, ENST00000493775, Hs2.383588.2.A1_3p_x_at, g4885608_3p_a_at |
| Search EB-eye |
ENSG00000197122
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