ARHGEF12
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Homo sapiens |
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ARHGEF12 is differentially expressed in 323 experiments: 145 organism parts: heart, liver, ... (143 more);, 241 disease states: normal, glioblastoma, ... (239 more);, 121 cell types 404 cell lines 42 compound treatments and 88 other conditions. |
| Synonyms |
LARG, KIAA0382 |
| Orthologs |
Arhgef12
(Mus musculus)
ARHGEF12
(Bos taurus)
Arhgef12
(Rattus norvegicus)
ARHGEF12
(Gallus gallus)
ARHGEF12 (1 of 2)
(Danio rerio)
ARHGEF12 (2 of 2)
(Danio rerio)
RhoGEF2
(Drosophila melanogaster)
arhgef12
(Xenopus laevis)
ARHGEF12
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, protein binding, apoptosis, cytoplasm, intracellular, membrane, G-protein coupled receptor protein signaling pathway, G-protein-coupled receptor binding, regulation of Rho protein signal transduction, guanyl-nucleotide exchange factor activity, GTPase activator activity, axon guidance, small GTPase mediated signal transduction, regulation of small GTPase mediated signal transduction, Rho guanyl-nucleotide exchange factor activity, induction of apoptosis by extracellular signals, nerve growth factor receptor signaling pathway, intracellular signal transduction |
| Gene Ontology ID |
GO:0016020, GO:0007186, GO:0007264, GO:0007411, GO:0051056, GO:0005622, GO:0005515, GO:0006915, GO:0005737, GO:0005829, GO:0005085, GO:0005089, GO:0005096, GO:0001664, GO:0035023, GO:0048011, GO:0008624, GO:0035556 |
| InterPro ID |
IPR001478, IPR000219, IPR015212, IPR001849 |
| InterPro Term |
Regulat_G_prot_signal-like, PDZ/DHR/GLGF, Pleckstrin_homology, DH-domain |
| Ensembl Family Description |
RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR |
| Ensembl Family |
ENSFM00600000921196 |
| Description |
Rho guanine nucleotide exchange factor (GEF) 12 [Source:HGNC Symbol;Acc:14193] |
| Ensembl Gene ID |
ENSG00000196914 |
| EMBL-Bank ID |
AB002380, BC063117, AF180681, AK304316, AP001150, AP000659, AP000758 |
| Ensembl Protein ID |
ENSP00000380942, ENSP00000349056, ENSP00000432984 |
| Entrez Gene ID |
23365 |
| UniGene ID |
Hs.24598, Hs.621937, Hs.606621 |
| UniProt Accession |
Q9NZN5, B4E2K6, E9PMR6 |
| RefSeq ID |
NM_015313, NP_056128, NP_001185594, NM_001198665 |
| HGNC Symbol |
ARHGEF12 |
| Ensembl Transcript ID |
ENST00000532993, ENST00000530747, ENST00000532823, ENST00000528681, ENST00000526067, ENST00000530388, ENST00000528225, ENST00000356641, ENST00000397843, ENST00000525222, ENST00000529970, ENST00000525960, ENST00000531616 |
| Gene-Disease Assocation |
LEUKEMIA, ACUTE MYELOID; AML |
| Design Element |
201335_s_at, 44179_at, Hs.306461.0.S1_3p_x_at, g7662087_3p_a_at, ENST00000529970, ENST00000530388, ENST00000528681, ENST00000532993, Hs2.425275.1.A1_3p_at, 35772_at, ENST00000525222, 201334_s_at, Hs2.374682.1.S1_3p_at, g7770232_RC_3p_a_at, 234129_at, ENST00000356641, AB002380_at, ENST00000531616, 1555498_at, ENST00000532823, ENST00000397843, ENST00000528225, Hs.306461.0.S1_3p_s_at, 1559833_at, ENST00000530747, 201333_s_at, ENST00000525960, Hs.6582.0.A2_3p_a_at, Hs.6582.0.A1_3p_a_at, ENST00000526067 |
| Search EB-eye |
ENSG00000196914
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