ADA
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Homo sapiens |
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ADA is differentially expressed in 344 experiments: 113 organism parts: thymus, kidney, ... (111 more);, 218 disease states: normal, control, ... (216 more);, 110 cell types 439 cell lines 51 compound treatments and 81 other conditions. |
| Orthologs |
AAH1
(Saccharomyces cerevisiae)
F6WSV9_CIOIN
(Ciona intestinalis)
ada
(Danio rerio)
A6H7A2_BOVIN
(Bos taurus)
Ada
(Mus musculus)
F1P2A6_CHICK
(Gallus gallus)
Ada
(Rattus norvegicus)
ada.2
(Xenopus laevis)
ada
(Xenopus laevis)
Q9XT63_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0009897, GO:0009986, GO:0008270, GO:0016020, GO:0007155, GO:0007568, GO:0004000, GO:0048566, GO:0042542, GO:0016787, GO:0005615, GO:0005515, GO:0005737, GO:0005886, GO:0005829, GO:0005764, GO:0043066, GO:0043025, GO:0046872, GO:0019239, GO:0031410, GO:0006144, GO:0001666, GO:0045187, GO:0030054, GO:0009117, GO:0009168, GO:0060407, GO:0010460, GO:0060169, GO:0002636, GO:0002686, GO:0048541, GO:0046085, GO:0046061, GO:0002314, GO:0048286, GO:0030890, GO:0046101, GO:0046103, GO:0046111, GO:0050728, GO:0043101, GO:0050850, GO:0050870, GO:0050862, GO:0032839, GO:0042110, GO:0001701, GO:0043278, GO:0001889, GO:0001890, GO:0045582, GO:0045580, GO:0001829, GO:0001821, GO:0001883, GO:0045987, GO:0046638, GO:0006157, GO:0006154, GO:0070256, GO:0070244, GO:0033632, GO:0002906, GO:0030324, GO:0032261, GO:0033089, GO:0043103, GO:0060205, GO:0042323, GO:0055086 |
| Gene Ontology Term |
cytosol, response to hydrogen peroxide, plasma membrane, protein binding, cytoplasm, extracellular space, embryonic digestive tract development, membrane, lysosome, negative regulation of apoptosis, metal ion binding, nucleotide metabolic process, response to hypoxia, cell junction, external side of plasma membrane, cell adhesion, purine ribonucleoside monophosphate biosynthetic process, aging, deaminase activity, cytoplasmic vesicle, hydrolase activity, adenosine deaminase activity, cell surface, regulation of circadian sleep/wake cycle, sleep, purine base metabolic process, zinc ion binding, neuronal cell body, xanthine biosynthetic process, positive regulation of T cell activation, purine nucleoside binding, hypoxanthine biosynthetic process, positive regulation of B cell proliferation, Peyer's patch development, positive regulation of heart rate, positive regulation of smooth muscle contraction, adenosine metabolic process, regulation of T cell differentiation, in utero embryonic development, negative regulation of thymocyte apoptosis, positive regulation of germinal center formation, regulation of cell-cell adhesion mediated by integrin, response to morphine, deoxyadenosine catabolic process, T cell activation, placenta development, positive regulation of alpha-beta T cell differentiation, negative regulation of inflammatory response, lung alveolus development, negative regulation of adenosine receptor signaling pathway, negative regulation of leukocyte migration, negative regulation of mature B cell apoptosis, negative regulation of penile erection, purine nucleotide salvage, positive regulation of calcium-mediated signaling, histamine secretion, germinal center B cell differentiation, lung development, positive regulation of T cell differentiation, dATP catabolic process, liver development, inosine biosynthetic process, adenosine catabolic process, negative regulation of mucus secretion, trophectodermal cell differentiation, dendrite cytoplasm, positive regulation of T cell receptor signaling pathway, hypoxanthine salvage, positive regulation of T cell differentiation in thymus, purine-containing compound salvage, cytoplasmic membrane-bounded vesicle lumen, negative regulation of circadian sleep/wake cycle, non-REM sleep, nucleobase-containing small molecule metabolic process |
| InterPro ID |
IPR001365, IPR006330 |
| InterPro Term |
A/AMP_deaminase, A_deaminase |
| Ensembl Family |
ENSFM00250000004973 |
| Ensembl Family Description |
ADENOSINE DEAMINASE EC_3.5.4.4 ADENOSINE AMINOHYDROLASE |
| Ensembl Gene ID |
ENSG00000196839 |
| UniProt Accession |
P00813, F5GWI4, F5GXW0, F5GYD4 |
| Ensembl Protein ID |
ENSP00000361965, ENSP00000441818, ENSP00000446464, ENSP00000440946 |
| EMBL-Bank ID |
BC040226, AK223397, Z97053, BC007678, X02189, X02199, X02197, X02198, X02194, X02195, X02196, X02192, X02193, X02190, X02191, AL139352, M13792, X02994 |
| Gene-Disease Assocation |
SEVERE COMBINED IMMUNODEFICIENCY, AUTOSOMAL RECESSIVE, T CELL-NEGATIVE, |
| UniGene ID |
Hs.705972 |
| HGNC Symbol |
ADA |
| Description |
adenosine deaminase [Source:HGNC Symbol;Acc:186] |
| RefSeq ID |
NP_000013, NM_000022 |
| Entrez Gene ID |
100 |
| Ensembl Transcript ID |
ENST00000545776, ENST00000536532, ENST00000492931, ENST00000539235, ENST00000372874, ENST00000537820, ENST00000536076, ENST00000464097, ENST00000535573 |
| Design Element |
ENST00000464097, 216705_s_at, ENST00000535573, ENST00000536532, 41654_at, 907_at, ENST00000537820, ENST00000545776, Hs.1217.1.S1_3p_a_at, ENST00000536076, ENST00000372874, ENST00000539235, M13792_at, 204639_at, ENST00000492931 |
| Search EB-eye |
ENSG00000196839
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