MKL1
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Homo sapiens |
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MKL1 is differentially expressed in 302 experiments: 139 organism parts: bone marrow, kidney, ... (137 more);, 236 disease states: normal, acute myeloid leukemia, ... (234 more);, 106 cell types 387 cell lines 49 compound treatments and 84 other conditions. |
| Synonyms |
KIAA1438, MAL, MRTF-A, BSAC |
| Orthologs |
ENSCING00000009545
(Ciona intestinalis)
Mkl1
(Mus musculus)
Mkl1
(Rattus norvegicus)
MKL1 (1 of 2)
(Danio rerio)
MKL1
(Bos taurus)
MKL1
(Gallus gallus)
MKL1 (2 of 2)
(Danio rerio)
Mrtf
(Drosophila melanogaster)
mkl1
(Xenopus laevis)
MKL1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0003676, GO:0003785, GO:0003779, GO:0003713, GO:0005515, GO:0006916, GO:0005737, GO:0005634, GO:0045944, GO:0045893, GO:0051145, GO:0043522 |
| Gene Ontology Term |
protein binding, actin monomer binding, cytoplasm, nucleic acid binding, anti-apoptosis, positive regulation of transcription from RNA polymerase II promoter, transcription coactivator activity, nucleus, positive regulation of transcription, DNA-dependent, actin binding, leucine zipper domain binding, smooth muscle cell differentiation |
| InterPro Term |
RPEL_repeat, SAP_DNA-bd |
| InterPro ID |
IPR004018, IPR003034 |
| Description |
megakaryoblastic leukemia (translocation) 1 [Source:HGNC Symbol;Acc:14334] |
| EMBL-Bank ID |
AL713710, AJ297258, AJ297257, BC114364, AL022238, AB037859, CH471095, AF368061, AJ303089, AJ303090, AF364035, CR456522, Z86090, AL031594 |
| Ensembl Protein ID |
ENSP00000398478, ENSP00000385835, ENSP00000385584, ENSP00000385076, ENSP00000379861, ENSP00000347847, ENSP00000443802 |
| Ensembl Gene ID |
ENSG00000196588 |
| HGNC Symbol |
MKL1 |
| UniGene ID |
Hs.654688, Hs.668708 |
| RefSeq ID |
NM_020831, NP_065882 |
| UniProt Accession |
Q29R68, Q969V6, B0QY84, B0QY83, B0QY74, E7ER32, E9PCL0 |
| Entrez Gene ID |
57591 |
| Ensembl Family |
ENSFM00630001050606 |
| Ensembl Family Description |
MKL/MYOCARDIN 1 MEGAKARYOBLASTIC LEUKEMIA 1 MYOCARDIN RELATED TRANSCRIPTION FACTOR A MRTF A |
| Ensembl Transcript ID |
ENST00000355630, ENST00000422851, ENST00000463769, ENST00000402042, ENST00000477468, ENST00000499213, ENST00000466278, ENST00000402630, ENST00000407029, ENST00000396617 |
| Design Element |
ENST00000463769, Hs.31146.0.S1_3p_at, ENST00000402630, 215292_s_at, ENST00000499213, 35629_at, ENST00000396617, ENST00000402042, 215291_at, Hs.134751.0.A1_3p_s_at, ENST00000407029, 215291_3p_at, ENST00000477468, ENST00000422851, Hs2.433153.2.S1_3p_at, ENST00000466278, Hs.134751.0.A1_3p_at, 212748_at, 1555763_x_at, ENST00000355630, 35563_at, 1559902_at, Hs2Affx.1.461.S1_3p_x_at |
| Search EB-eye |
ENSG00000196588
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