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CLDN4
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Homo sapiens
CLDN4 is differentially expressed in 224 experiments: 150 organism parts: lung, prostate, ... (148 more);, 195 disease states: normal, lung adenocarcinoma, ... (193 more);, 64 cell types 544 cell lines 30 compound treatments and 62 other conditions.
Synonyms CPETR, CPE-R, WBSCR8, hCPE-R, CPETR1
Orthologs CLDN4 (1 of 6) (Danio rerio)   cldnb (Danio rerio)   cldnd (Danio rerio)   CLDN4 (6 of 6) (Danio rerio)   cldna (Danio rerio)   cldne (Danio rerio)   CLD4_BOVIN (Bos taurus)   Cldn4 (Mus musculus)   Cldn4 (Rattus norvegicus)   cldn4 (Xenopus laevis)   CLDN4 (Canis familiaris)   (Compare orthologs)
Gene Ontology Term plasma membrane, protein binding, membrane, structural molecule activity, tight junction, cell junction, apicolateral plasma membrane, identical protein binding, calcium-independent cell-cell adhesion, integral to plasma membrane, apical plasma membrane, integral to membrane, basal plasma membrane, lateral plasma membrane, female pregnancy, response to progesterone stimulus, transmembrane signaling receptor activity
InterPro Term Claudin, PMP22/EMP/MP20/Claudin, Claudin4
UniProt Accession Q75L80, O14493, B3KW38
Search EB-eye ENSG00000189143
Show more properties
Experimental Factors
Organism part

studied in E-GEOD-17189, E-GEOD-15765, E-GEOD-803, E-GEOD-6573, E-GEOD-2549, ... (27 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-17482, E-GEOD-5258, E-GEOD-19639, E-GEOD-18005, E-GEOD-19397, ... (32 experiments)

Factor Value U/D Experiments
SW480
3
E-MEXP-1014, E-MTAB-37, E-GEOD-18005
primary culture
2
E-GEOD-1657, E-GEOD-2450
AGS
2
E-MTAB-37, E-GEOD-15460
BT20
2
E-MTAB-37, E-MTAB-62
BT474
2
E-MTAB-37, E-MTAB-62
CCRFCEM
2
E-MTAB-37, E-GEOD-24147
538 more value(s).


Cell type

studied in E-GEOD-22373, E-GEOD-19397, E-GEOD-3920, E-MEXP-66, E-GEOD-20677, ... (34 experiments)

Factor Value U/D Experiments
CD4+ T cell
1
E-MTAB-24
n/a
1
E-MTAB-24
normal
1
E-GEOD-6883
primary fibroblast
1
E-MEXP-66
primary human mammary epithelial cells
1
E-GEOD-29119
interstitial stromal cells
1
E-GEOD-20758
58 more value(s).


Disease state

studied in E-GEOD-3307, E-GEOD-6872, E-GEOD-15960, E-GEOD-1869, E-GEOD-2466, ... (48 experiments)

Factor Value U/D Experiments
lung adenocarcinoma
4
E-MTAB-37, E-MTAB-62, E-GEOD-2514, E-MEXP-231
control
3
E-GEOD-16363, E-GEOD-21912, E-GEOD-20295
prostate carcinoma
1
3
E-MTAB-62, E-MEXP-2034, E-GEOD-7307, E-GEOD-96
choriocarcinoma
2
E-MTAB-37, E-MTAB-62
gastric carcinoma
2
E-MTAB-37, E-GEOD-15460
neuroblastoma
2
E-MTAB-62, E-MTAB-37
189 more value(s).


Compound treatment

studied in E-GEOD-6907, E-GEOD-5824, E-GEOD-3720, E-TABM-868, E-GEOD-6462, ... (16 experiments)

Factor Value U/D Experiments
none
3
4
E-MEXP-1230, E-GEOD-412, E-GEOD-2292, E-GEOD-2803, E-MEXP-1601, ... (7 experiments)
5-aza-2'-deoxycytidine + trichostatin A
1
1
E-MEXP-1269
2,3-dimethoxy-1,4-naphthoquinone
1
E-GEOD-6907
N-nitrosodimethylamine
1
E-GEOD-6907
unknown
1
E-GEOD-7307
granulocyte macrophage-colony stimulating factor
1
E-GEOD-2803
24 more value(s).


Agent

studied in E-GEOD-19519

Factor Value U/D Experiments
thapsigargin
1
E-GEOD-19519
tunicamycin
1
E-GEOD-19519


Biosource provider
studied in E-MTAB-37, E-GEOD-20559

BioSourceProvider
studied in E-GEOD-19519, E-GEOD-19480

Blood/non-blood meta-groups
studied in E-MTAB-62

Bmngrd
studied in E-GEOD-20194, E-GEOD-16716

Cancer site
studied in E-GEOD-4271

Cell treatment
studied in E-MEXP-1192

Cellular component
studied in E-GEOD-1400

Clinical history
studied in E-GEOD-22097, E-GEOD-19743, E-GEOD-7967, E-GEOD-2171, E-GEOD-21589, ... (7 experiments)

Clinical info
studied in E-GEOD-19743, E-MTAB-37, E-GEOD-19348, E-MEXP-1251, E-GEOD-21374, ... (8 experiments)

Clinical treatment
studied in E-GEOD-6532

coriell cell line repository identifier
studied in E-GEOD-19519

Developmental stage
studied in E-GEOD-19743, E-GEOD-1614, E-GEOD-3140, E-MEXP-2359, E-MTAB-62 ... (5 experiments)

Disease stage
studied in E-GEOD-7463

Disease staging
studied in E-GEOD-1323, E-GEOD-19743, E-TABM-147, E-GEOD-21138, E-GEOD-3013 ... (5 experiments)

Environmental stress
studied in E-GEOD-3720

Estrogen receptor status
studied in E-GEOD-6532

Ethnic group
studied in E-GEOD-20194, E-GEOD-16716

family id
studied in E-GEOD-19519

Family relationship
studied in E-MEXP-1425

Genetic modification
studied in E-GEOD-8023, E-MTAB-73, E-MEXP-2340

Genotype
studied in E-GEOD-2466, E-GEOD-17476, E-MEXP-421, E-TABM-321, E-TABM-868, ... (8 experiments)

Gestation age
studied in E-GEOD-14334

369 groups
studied in E-MTAB-62

4 groups from blood to incompletely diff
studied in E-MTAB-62

96 groups
studied in E-MTAB-62

Growth condition
studied in E-TABM-263, E-GEOD-5681, E-GEOD-20540, E-MEXP-1446, E-MEXP-1103, ... (6 experiments)

Her2 ihc
studied in E-GEOD-20194, E-GEOD-16716

Her2 status
studied in E-GEOD-20194, E-GEOD-16716

Histology
studied in E-GEOD-2748

Individual
studied in E-MTAB-197, E-TABM-176, E-GEOD-1926, E-TABM-666, E-GEOD-19330, ... (21 experiments)

Infection
studied in E-GEOD-12108, E-GEOD-12254, E-MEXP-561, E-GEOD-980, E-GEOD-923 ... (5 experiments)

Injury
studied in E-GEOD-19743

Material type
studied in E-GEOD-9171

15 meta groups
studied in E-MTAB-62

4 meta groups
studied in E-MTAB-62

6 meta groups
studied in E-MTAB-62

Metastasis
studied in E-GEOD-18105

Molecular subtype
studied in E-GEOD-21653

organ
studied in E-GEOD-24283

Organism
studied in E-GEOD-1801, E-TABM-84

Phase
studied in E-GEOD-4888

Phenotype
studied in E-GEOD-22309, E-GEOD-21750, E-GEOD-1657

Population
studied in E-GEOD-4922

Progesterone receptor status
studied in E-GEOD-6532

Protocol type
studied in E-GEOD-22097, E-GEOD-3254, E-GEOD-19445, E-GEOD-19246, E-GEOD-1343 ... (5 experiments)

Qpcr egfr dct
studied in E-GEOD-5851

Replicate
studied in E-GEOD-10797

RNAi
studied in E-GEOD-12438, E-MEXP-101, E-GEOD-3697

Sample preparation
studied in E-GEOD-16728

sampleID
studied in E-GEOD-24283

Sampling time point
studied in E-GEOD-19743, E-GEOD-17400

Sex
studied in E-GEOD-1643, E-GEOD-2466, E-GEOD-7307, E-TABM-147

Stimulation
studied in E-GEOD-20114, E-GEOD-11428

Subtype
studied in E-GEOD-24283

Survival time
studied in E-GEOD-19188

Tbefore
studied in E-GEOD-20194, E-GEOD-16716

Test result
studied in E-GEOD-1926, E-GEOD-2748

Treatment
studied in E-GEOD-16837, E-GEOD-19246, E-GEOD-13818

Treatment code
studied in E-GEOD-20194, E-GEOD-16716

Tumor grading
studied in E-GEOD-4922

Vehicle
studied in E-GEOD-5258

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM