MAPK12
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Homo sapiens |
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MAPK12 is differentially expressed in 304 experiments: 120 organism parts: skeletal muscle, mammary gland, ... (118 more);, 183 disease states: normal, T cell acute lymphoblastic leukemia, ... (181 more);, 82 cell types 322 cell lines 155 compound treatments and 60 other conditions. |
| Synonyms |
SAPK-3, PRKM12, ERK6, SAPK3, p38gamma |
| Orthologs |
HOG1
(Saccharomyces cerevisiae)
MAPK12 (1 of 2)
(Danio rerio)
MAPK12
(Gallus gallus)
mapk12
(Danio rerio)
Mapk12
(Mus musculus)
A5PJL3_BOVIN
(Bos taurus)
Mapk12
(Rattus norvegicus)
mapk12
(Xenopus tropicalis)
MAPK12
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001245, IPR000719, IPR008352, IPR020635 |
| Gene Ontology Term |
cytosol, protein binding, cytoplasm, cell cycle arrest, protein tyrosine kinase activity, MAP kinase activity, soluble fraction, ATP binding, Ras protein signal transduction, magnesium ion binding, transferase activity, transferring phosphorus-containing groups, muscle organ development, muscle cell differentiation, nucleotide binding, protein serine/threonine kinase activity, nucleoplasm, negative regulation of cell cycle, signal transduction, protein kinase activity, mitochondrion, myoblast differentiation, DNA damage induced protein phosphorylation, nerve growth factor receptor signaling pathway, positive regulation of muscle cell differentiation, protein phosphorylation |
| Gene Ontology ID |
GO:0007050, GO:0007165, GO:0007265, GO:0007517, GO:0016772, GO:0004707, GO:0004713, GO:0042692, GO:0005625, GO:0005524, GO:0005515, GO:0005737, GO:0005739, GO:0005654, GO:0005829, GO:0004672, GO:0004674, GO:0006468, GO:0000166, GO:0045786, GO:0000287, GO:0048011, GO:0051149, GO:0006975, GO:0045445 |
| Ensembl Family Description |
MITOGEN ACTIVATED KINASE MAP KINASE EC_2.7.11.24 |
| Ensembl Family |
ENSFM00460000244923 |
| EMBL-Bank ID |
Y10487, X79483, AL022328, CH471138, BC015741, U66243 |
| Entrez Gene ID |
6300 |
| UniProt Accession |
A8MY48, B5MDL5, P53778, F6TXG5 |
| Ensembl Protein ID |
ENSP00000379126, ENSP00000379124, ENSP00000215659, ENSP00000404167 |
| Description |
mitogen-activated protein kinase 12 [Source:HGNC Symbol;Acc:6874] |
| UniGene ID |
Hs.432642 |
| RefSeq ID |
NP_002960, NM_002969 |
| HGNC Symbol |
MAPK12 |
| Ensembl Gene ID |
ENSG00000188130 |
| Ensembl Transcript ID |
ENST00000482969, ENST00000438835, ENST00000497036, ENST00000488504, ENST00000467891, ENST00000497738, ENST00000395778, ENST00000395780, ENST00000492218, ENST00000496942, ENST00000215659 |
| InterPro Term |
Tyrosine-protein kinase, catalytic domain, MAP kinase, p38, Protein kinase, catalytic domain, Serine/threonine- / dual-specificity protein kinase, catalytic domain, Serine-threonine/tyrosine-protein kinase catalytic domain |
| GeneSigDB ID |
16705456-Table2, 20460173-ImmPortCD40LvsControl, 19808870-ST1, 19341462-SuppTable2, 15256063-Table1a, 15067324-Table3S, 12917485-Table8, 18160665-TableS5, 15705876-TableS6, 16728581-SuppTable1, 19505326-SuppTable3, 16207381-Table1Sa |
| Design Element |
984_g_at, ENST00000395778, 226672_s_at, ENST00000215659, Hs.26593.0.S1_3p_a_at, 206106_at, ENST00000488504, ENST00000395780, X79483_at, Hs.55039.0.S2_3p_at, ENST00000467891, Hs2.432642.1.S1_3p_s_at, 51132_at, ENST00000482969, ENST00000497036, ENST00000492218, 63649_at, ENST00000496942, ENST00000438835, 1556341_s_at, 1556340_at, ENST00000497738, Hs.55039.0.S2_3p_x_at |
| EMAGE ID |
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| Search EB-eye |
ENSG00000188130
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