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FANCA Homo sapiens
FANCA is differentially expressed in 125 experiments [155 up/137 dn]: 30 organism parts: testis [2 up/0 dn], bone marrow [1 up/1 dn], ...; 39 disease states: normal [6 up/9 dn], glioblastoma [2 up/0 dn], ...; 37 cell types, 39 cell lines, 25 compound treatments and 20 other conditions.
Synonyms FAA, FACA, FANCA, FANCH
Orthologs NP_001101925.1 (Rattus norvegicus)  Fanca (Mus musculus)  (Compare orthologs)
InterPro Term Fanconi anaemia group A protein
Diseases Fanconi anemia, complementation group A
GO Terms DNA repair, cytoplasm, female gonad development, male meiosis, protein binding
Uniprot O15360  Q0VAP3  Q0VAP4  Q86U55 
Search EB-eye ENSG00000187741
REST API
Expression Summary
243 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
9
6
None Compound treatment
3
3
HeLa Cell line
1
2
Stromal cell Cell type
2
1
Glioblastoma Disease state
2
FLAP Compound treatment
2
PC3 Cell line
1
1
MK886 Compound treatment
2
Cervical cancer Disease state
2
Testis Organism part
2
Caco-2 Cell line
2
MDA-MB-231 Cell line
2
HNRPA2B Compound treatment
2
HL-60 Cell line
1
1
Invasive ductal carcinoma Histology
2
Breast carcinoma Disease state
1
1
N/a Test result
1
1
Fibroblast Cell type
1
1
0 cm away from the tumor bound... Observation
2
Not applicable Histology
1
1
Homo sapiens Organism
2
Bone marrow Organism part
1
1
ERalpha transfected Genotype
1
1
Estrogen receptor 1 negative; ... Test result
2
Estrogen receptor 1 positive; ... Test result
2
MCF-7 Cell line
1
1
BT-474 Cell line
1
1
Epithelial cell Cell type
1
1
Endothelial cell Cell type
1
1
Monocyte Cell type
1
1
MCF7 Cell line
1
SW480 Cell line
1
SW620 Cell line
1
SsMCF7 Cell line
1
Adipose-derived stem cell Cell type
1
Glucocorticoid resistant Phenotype
1
Glucocorticoid sensitive Phenotype
1
Pretreatment primary sample Clinical info
1
Cerebellum Organism part
1
SKMEL5 Cell line
1
SKBR3 Cell line
1
Kidney cell Cell type
1
Dimethyl sulfoxide Compound treatment
1
Grade IV Tumor grading
1
Rapamycin Compound treatment
1
Lymphatic endothelial cell Cell type
1
Johnsen score count 3.2: Serto... Histology
1
Vascular smooth muscle cell Cell type
1
Benign prostatic hyperplasia Disease state
1
Prostate carcinoma Disease state
1
Primary cells Cell line
1
Spermatocyte Cell type
1
Acute promyelocytic leukemia Disease state
1
U937 Cell line
1
Chondrocyte Cell type
1
U266 Cell line
1
Malignant melanoma Disease state
1
Thymus Organism part
1
Lymph node Organism part
1
Tonsil Organism part
1
Osteoblast Cell type
1
Uterine cervix Organism part
1
Prostate Organism part
1
MDA468 Cell line
1
ERbeta transfected Genotype
1
White blood cells Organism part
1
HPL1 Cell line
1
Tumor Organism part
1
Organism_part Material type
1
Cell Material type
1
T47D Cell line
1
Experimental malaria-infected Disease state
1
Adenocarcinoma Disease state
1
Skeletal muscle Organism part
1
CodeLink Labeling Protocol type
1
Spermatid Cell type
1
Epidermal growth factor Compound treatment
1
Plasmacytoid dendritic cell Cell type
1
T84 Cell line
1
Cartilage Organism part
1
MCF10A Cell line
1
Training set Population
1
Test set Population
1
Baseline uninfected Disease state
1
Enzo Labeling Protocol type
1
Seminiferous tubule Organism part
1
BCBL-1 Cell line
1
Frontal cortex, primary motor ... Organism part
1
Uninfected Infection
1
HaCaT Cell line
1
Caudate nucleus Organism part
1
Trichostatin A Compound treatment
1
CD3- CD4+ CD8- Phenotype
1
Intrathymic T progenitor cell Cell type
1
Treated malaria, natural infec... Disease state
1
Beas2B Cell line
1
Kaposi's sarcoma-associated he... Infection
1
Serum starvation synchronizati... Growth condition
1
Bacterial endotoxin Compound treatment
1
Control Compound treatment
1
Native skin Cell type
1
Trigeminal ganglion Organism part
1
Acute malaria, natural infecti... Disease state
1
Dermal fibroblast Cell type
1
Lipopolysaccharide Compound treatment
1
Senescence bypassed Phenotype
1
T-cell acute lymphoblastic leu... Disease state
1
Metastatic Disease staging
1
Multiple myeloma Disease state
1
T3aN0Mx Disease staging
1
Epilepsy Disease state
1
None Gene modification
1
Stage I Disease staging
1
Relapse 0; ER status ER+; brai... Clinical info
1
G3 Tumor grading
1
T-cell lymphoblastic lymphoma Disease state
1
Plasma cell Cell type
1
B lymphocyte Cell type
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
Serum starvation + thymidine b... Growth condition
1
T3aNxM1 Disease staging
1
Johnsen score count 7: many ea... Histology
1
MM1 Cell line
1
Skin Organism part
1
Control RNAi
1
SIM2s RNAi
1
Testis - seminiferous tubule Organism part
1
White blood cell Cell type
1
Platelet Cell type
1
Primary culture 2 Cell line
1
Heat-killed HL60 cell lysate Infection
1
Capra hircus Organism
1
Lymphoid tissue Organism part
1
Carboplatin resistant Test result
1
Carboplatin sensitive Test result
1
Hypericin incubated, not irrad... Growth condition
1
Hypericin incubated, irradiate... Growth condition
1
Keratinocyte Cell type
1
ITM-E6E7-ST Cell line
1
Epidermal keratinocyte Cell type
1
SkinEthic keratinocyte Cell type
1
Johnsen score count 2: Sertoli... Histology
1
CD3+ CD4+ CD8- CD45RA+ CD62L+ Phenotype
1
Naive T cell Cell type
1
Superficial transitional cell ... Disease state
1
Fetal lung Organism part
1
Ductal carcinoma in situ Disease state
1
Invasive ductal carcinoma Disease state
1
Frontal cortex, superior motor... Organism part
1
Granulocyte Cell type
1
Vulvar intraepithelial neoplas... Disease state
1
Arsenic oxide Compound treatment
1
Testis - interstitial Organism part
1
Lung Organism part
1
Granulocyte macrophage-colony ... Compound treatment
1
Cystic change Histology
1
Permanent atrial fibrillation Disease state
1
No atrial fibrillation Disease state
1
ITM-E6E7 Cell line
1
Monocyte at intermediate diffe... Cell type
1
Skin substitute Cell type
1
Johnsen score count 8: hypospe... Histology
1
NCI-H929 Cell line
1
Senescence induced Phenotype
1
ITM Cell line
1
TIVE Cell line
1
Breast cancer Disease state
1
ERalpha L540Q transfected Genotype
1
Hematopoietic stem cell Cell type
1
Adipose tissue-derived stem ce... Cell type
1
Waldenstrom's macroglobulinemi... Disease state
1
Platelet-derived growth factor Compound treatment
1
A549 Cell line
1
Esophageal adenocarcinoma Disease state
1
T3aNxMx Disease staging
1
Johnsen score count 5: no sper... Histology
1
Geriatric Developmental stage
1
Pediatric Developmental stage
1
Wild_type Genotype
1
Jurkat Cell line
1
Uterus Organism part
1
Papillary thyroid carcinoma Disease state
1
Control for heregulin Compound treatment
1
Cadmium chloride 2.5-hydrate Compound treatment
1
Idiopathic cardiomyopathy Disease state
1
Chloroguine Compound treatment
1
Down syndrome Disease state
1
DMSO Vehicle
1
Smooth muscle Organism part
1
Whole blood Organism part
1
TaN0M0 Disease staging
1
Empty vector Gene modification
1
CD3int CD4+ CD8+ Phenotype
1
Double positive thymocyte Cell type
1
Stage II Disease staging
1
ITV Cell line
1
Ethanol Vehicle
1
Mercaptopurine, methotrexate Compound treatment
1
Grade II Tumor grading
1
Keratinocyte growth factor Compound treatment
1
5-aza-2'-deoxycytidine Compound treatment
1
Colorectal cancer recurrence Disease state
1
Colorectal cancer recurrence-f... Disease state
1
CD105+ endothelial Cell type
1
Multipotent adult progenitor c... Cell type
1
Mesenchymal stem cell Cell type
1
Temporal lobe Organism part
1
Control Phenotype
1
ITM-ST Cell line
1
Cancer27 Replicate
1
Superior cervical ganglion Organism part
1
Macaca mulatta Organism
1
CD34+ Cell type
1
GLI56 Cell line
1
Idiopathic dilated cardiomyopa... Disease state
1
Primary fibroblast Cell type
1
Lung adenocarcinoma Disease state
1
Cyclosporin A, mycophenolate m... Clinical treatment
1
Sirolimus, mycophenolate mofet... Clinical treatment
1
Bis [(+)-tartrato] diantimonat... Compound treatment
1
Primary Disease staging
1
B-precursor acute lymphoblasti... Disease state
1
Astrocyte Cell type
1
Proliferative Developmental stage
1
Differentiated Developmental stage
1
Superficial transitional cell ... Disease state
1
Serum deprivation Growth condition
1
GLI60 Cell line
1
Renal dysfunction without reje... Clinical info
1
Normal Histology
1
Undifferentiated Developmental stage
1
KSHV latent infection Disease state
1
BC-2 Cell line
1
Beta cell islets Organism part
1
Hydrogen peroxide Compound treatment
1
Nocodazole Compound treatment
1
Hydroxyurea Compound treatment
1
Parietal lobe Organism part
1
Benign Disease staging
1
Kaposi's sarcoma Disease state
1
R-(-)-apomorphine HCl Compound treatment
1
BC-3 Cell line
1
Expression Profiles
E-GEOD-5258: Transcription profiling of human cell lines freely cycling treated with 164 distinct small molecules - Broad Connectivity Map CMAP Set 1
Experimental Factors
Show expression profile  /  experiment details

 
E-MEXP-1014: Transcription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-5824: Transcription profiling of human Acute Lymphoblastic Leukemia CEM_C1 cells treated with rapamycin identifies rapamycin as a glucocorticoid resistance reversal agent
Experimental Factors
Phenotype Time Clinical info Dose Compound treatment
Show expression profile  /  experiment details

 
E-GEOD-4646: Transcription profiling of human HUVEC cells infected with Neisseria meningitidis wild type and mutants vs uninfected sampled at 3 time points
Experimental Factors
Time Infection
Show expression profile  /  experiment details

 
E-MEXP-1216: Transcription profiling of human adipose derived stem cells before induction and at two time points after induction of differentiation
Experimental Factors
Time Cell type Individual
Show expression profile  /  experiment details

 
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