BCR
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Homo sapiens |
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BCR is differentially expressed in 264 experiments: 97 organism parts: amygdala, caudate nucleus, ... (95 more);, 146 disease states: normal, glioblastoma, ... (144 more);, 86 cell types 382 cell lines 35 compound treatments and 74 other conditions. |
| Synonyms |
D22S11, BCR1, D22S662, PHL, CML, ALL |
| Orthologs |
BCR
(Bos taurus)
Bcr
(Rattus norvegicus)
ENSCING00000005571
(Ciona intestinalis)
Bcr
(Mus musculus)
BCR
(Gallus gallus)
bcr
(Xenopus laevis)
BCR
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, plasma membrane, protein binding, intracellular, regulation of Rho protein signal transduction, guanyl-nucleotide exchange factor activity, ATP binding, GTPase activator activity, actin cytoskeleton organization, small GTPase mediated signal transduction, regulation of cell cycle, negative regulation of cell migration, regulation of small GTPase mediated signal transduction, response to lipopolysaccharide, Rho guanyl-nucleotide exchange factor activity, nucleotide binding, kinase activity, protein serine/threonine kinase activity, transferase activity, brain development, signal transduction, positive regulation of GTPase activity, negative regulation of inflammatory response, neuromuscular process controlling balance, inner ear morphogenesis, positive regulation of Rac GTPase activity, positive regulation of phagocytosis, Rac GTPase activator activity, protein phosphorylation, negative regulation of neutrophil degranulation |
| InterPro ID |
IPR000008, IPR000198, IPR000219, IPR018029, IPR015123, IPR001849 |
| Gene Ontology ID |
GO:0007165, GO:0007264, GO:0016301, GO:0007420, GO:0051056, GO:0016740, GO:0005622, GO:0005524, GO:0005515, GO:0005886, GO:0005829, GO:0004674, GO:0032496, GO:0005085, GO:0005089, GO:0005096, GO:0006468, GO:0000166, GO:0051726, GO:0043547, GO:0030036, GO:0030336, GO:0035023, GO:0030675, GO:0042472, GO:0050766, GO:0050728, GO:0050885, GO:0032855, GO:0043314 |
| InterPro Term |
Bcr-Abl_oncoprot_oligo, C2_Ca-dep, Pleckstrin_homology, DH-domain, C2_membr_targeting, RhoGAP_dom |
| Ensembl Family |
ENSFM00250000000543 |
| Ensembl Family Description |
BREAKPOINT CLUSTER REGION |
| UniGene ID |
Hs.715409, Hs.551463, Hs.604560, Hs.517461 |
| UniProt Accession |
P11274, A9UF05, A9UF04, A9UF01, E9PGJ4 |
| EMBL-Bank ID |
X52829, X52828, EU216069, EU216065, EU216068, M15025, AB209991, Y00661, M64437, X02596, U07000, X14676 |
| Ensembl Gene ID |
ENSG00000186716 |
| Ensembl Protein ID |
ENSP00000335450, ENSP00000381524, ENSP00000290956, ENSP00000303507, ENSP00000396531, ENSP00000292697, ENSP00000352535, ENSP00000445910 |
| RefSeq ID |
NM_021574, NM_004327, NP_067585, NP_004318 |
| HGNC Symbol |
BCR |
| Entrez Gene ID |
613 |
| Description |
breakpoint cluster region [Source:HGNC Symbol;Acc:1014] |
| Ensembl Transcript ID |
ENST00000487968, ENST00000487679, ENST00000419722, ENST00000292697, ENST00000436990, ENST00000458056, ENST00000334149, ENST00000290956, ENST00000471452, ENST00000420248, ENST00000478978, ENST00000463770, ENST00000305877, ENST00000479188, ENST00000475025, ENST00000427791, ENST00000466076, ENST00000359540, ENST00000480973, ENST00000398512 |
| Gene-Disease Assocation |
LEUKEMIA, ACUTE LYMPHOBLASTIC; ALL, LEUKEMIA, CHRONIC MYELOID; CML |
| Design Element |
2043_s_at, ENST00000436990, ENST00000478978, 1333_f_at, 754_s_at, 68350_s_at, gnf1h07929_s_at, 91639_at, 537_f_at, ENST00000479188, ENST00000458056, 34679_at, ENST00000427791, Hs.296429.1.A1_3p_a_at, 217223_s_at, 91641_g_at, X02596_at, ENST00000398512, ENST00000471452, 74612_s_at, ENST00000420248, Hs.234799.2.S1_3p_a_at, ENST00000305877, Hs.296429.1.A1_3p_x_at, ENST00000480973, 1339_s_at, X14675_at, ENST00000463770, ENST00000334149, ENST00000466076, ENST00000487679, 202315_s_at, 226602_s_at, 64904_at, ENST00000359540, ENST00000475025, ENST00000292697, ENST00000290956, ENST00000487968, ENST00000419722 |
| Search EB-eye |
ENSG00000186716
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