SOCS1
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Homo sapiens |
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SOCS1 is differentially expressed in 303 experiments: 123 organism parts: lung, ovary, ... (121 more);, 172 disease states: normal, Burkitt's lymphoma, ... (170 more);, 91 cell types 368 cell lines 48 compound treatments and 80 other conditions. |
| Synonyms |
SSI-1, SOCS-1, TIP3, JAB, Cish1 |
| Orthologs |
Q4H2S6_CIOIN
(Ciona intestinalis)
B6RCQ2_CHICK
(Gallus gallus)
socs1
(Danio rerio)
SOCS1
(Bos taurus)
Socs1
(Mus musculus)
Socs1
(Rattus norvegicus)
socs1
(Xenopus laevis)
SOCS1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, insulin-like growth factor receptor binding, negative regulation of JAK-STAT cascade, protein binding, cytokine-mediated signaling pathway, cytoplasm, protein kinase binding, negative regulation of catalytic activity, response to lipopolysaccharide, response to drug, JAK-STAT cascade, negative regulation of insulin receptor signaling pathway, regulation of growth, response to cytokine stimulus, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, response to progesterone stimulus, protein kinase inhibitor activity, fat cell differentiation, organ regeneration, response to peptide hormone stimulus, response to estradiol stimulus, kinase inhibitor activity, negative regulation of tyrosine phosphorylation of Stat3 protein, regulation of protein phosphorylation, intracellular signal transduction, interferon-gamma-mediated signaling pathway, type I interferon-mediated signaling pathway, cellular response to amino acid stimulus |
| InterPro Term |
SH2, SOCS_C |
| InterPro ID |
IPR001496, IPR000980 |
| Gene Ontology ID |
GO:0007259, GO:0042493, GO:0005515, GO:0005737, GO:0005829, GO:0032496, GO:0005159, GO:0040008, GO:0046426, GO:0043086, GO:0019901, GO:0001932, GO:0019221, GO:0046627, GO:0034097, GO:0060338, GO:0060334, GO:0042518, GO:0004860, GO:0032570, GO:0031100, GO:0019210, GO:0043434, GO:0045444, GO:0032355, GO:0035556, GO:0060333, GO:0060337, GO:0071230 |
| Ensembl Family |
ENSFM00500000274454 |
| Ensembl Family Description |
SUPPRESSOR OF CYTOKINE SIGNALING 1 SOCS 1 JAK BINDING JAB STAT INDUCED STAT INHIBITOR 1 SSI 1 |
| EMBL-Bank ID |
U88326, AF132440, AB000676, AK127621, AB000734, CH471112, AB005043, Z46940, DQ086801 |
| UniGene ID |
Hs.50640 |
| UniProt Accession |
O15524, Q4JHT5 |
| RefSeq ID |
NP_003736, NM_003745 |
| Description |
suppressor of cytokine signaling 1 [Source:HGNC Symbol;Acc:19383] |
| Ensembl Protein ID |
ENSP00000329418 |
| Ensembl Gene ID |
ENSG00000185338 |
| Entrez Gene ID |
8651 |
| HGNC Symbol |
SOCS1 |
| Ensembl Transcript ID |
ENST00000332029 |
| Design Element |
48838_s_at, 210001_s_at, 209999_x_at, g2443364_3p_a_at, Hs.50640.0.A1_3p_a_at, 41592_at, ENST00000332029 |
| Search EB-eye |
ENSG00000185338
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