SRY
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Homo sapiens |
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SRY is differentially expressed in 130 experiments: 51 organism parts: blood, heart, ... (49 more);, 89 disease states: normal, "Classic-KS, HIV-, nodular (late) stage", ... (87 more);, 42 cell types 76 cell lines 14 compound treatments and 53 other conditions. |
| Synonyms |
TDF |
| Orthologs |
SRY_BOVIN
(Bos taurus)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003677, GO:0003700, GO:0003705, GO:0016607, GO:0007548, GO:0005515, GO:0005737, GO:0005634, GO:0043231, GO:0045893, GO:0030154, GO:0030238, GO:2000020 |
| Gene Ontology Term |
DNA binding, protein binding, nuclear speck, cytoplasm, intracellular membrane-bounded organelle, transcription factor binding, cell differentiation, sex differentiation, nucleus, positive regulation of transcription, DNA-dependent, male sex determination, sequence-specific DNA binding transcription factor activity, positive regulation of male gonad development, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity |
| InterPro ID |
IPR000910, IPR017253 |
| InterPro Term |
HMG_HMG1/HMG2, TF_Sry |
| Ensembl Family Description |
SEX DETERMINING REGION Y TESTIS DETERMINING FACTOR |
| EMBL-Bank ID |
AM884747, AM884750, HM026174, GU112253, S53156, AC006040, S56543, CH471115, DQ086141, X53772, L08063, L10102, L10101, FN568070, FN568071, FN568073, FN568074, FN568076, FN568075, FN568078, FN568077, FN568079, FN568069, FN568068, FN568067, FN568085, FN568086, FN568083, FN568084, FN568081, FN568082, FN568080, FN568088, FN568087, AY601852, AY601854, AY601853, AY601859, AY601856, AY601855, AY601857, AY601860, BC074923, BC074924, X96421, HM241142, HM241133, HM241136, HM362426 |
| Ensembl Gene ID |
ENSG00000184895 |
| HGNC Symbol |
SRY |
| RefSeq ID |
NM_003140, NP_003131 |
| UniProt Accession |
D6QZA4, Q05066, A7WPU8, Q6J4J1, D0VTX2, F5H6J8, F5H3H1 |
| Ensembl Protein ID |
ENSP00000372547, ENSP00000438917, ENSP00000437575 |
| Description |
sex determining region Y [Source:HGNC Symbol;Acc:11311] |
| UniGene ID |
Hs.1992 |
| Entrez Gene ID |
6736 |
| Ensembl Family |
ENSFM00440000236864 |
| Gene-Disease Assocation |
46,XY SEX REVERSAL 1; SRXY1, 46,XX SEX REVERSAL 1; SRXX1 |
| Ensembl Transcript ID |
ENST00000383070, ENST00000534739, ENST00000525526 |
| Design Element |
L10102_rna1_at, 32864_at, ENST00000525526, g4507224_3p_at, 207893_at, ENST00000534739, ENST00000383070 |
| Search EB-eye |
ENSG00000184895
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