NPM1
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Homo sapiens |
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NPM1 is differentially expressed in 297 experiments: 148 organism parts: liver, ovary, ... (146 more);, 252 disease states: normal, glioblastoma, ... (250 more);, 98 cell types 420 cell lines 39 compound treatments and 82 other conditions. |
| Synonyms |
NPM, B23 |
| Orthologs |
npm1b
(Danio rerio)
Q6LEK2_CHICK
(Gallus gallus)
npm1
(Danio rerio)
F1M6T8_RAT
(Rattus norvegicus)
npm1
(Xenopus laevis)
XM_861566.1
(Canis familiaris)
LOC479292
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0003676, GO:0008285, GO:0003723, GO:0003713, GO:0008104, GO:0007098, GO:0007165, GO:0042255, GO:0051259, GO:0042393, GO:0030529, GO:0051082, GO:0051092, GO:0042803, GO:0005515, GO:0006913, GO:0006916, GO:0006950, GO:0005730, GO:0005737, GO:0005634, GO:0005654, GO:0006886, GO:0005856, GO:0005813, GO:0043024, GO:0031616, GO:0006334, GO:0046982, GO:0006281, GO:0034080, GO:0007569, GO:0051059, GO:0030957, GO:0043023, GO:0044419, GO:0010826, GO:0060699, GO:0032071 |
| Gene Ontology Term |
protein localization, protein binding, DNA repair, cytoskeleton, cytoplasm, histone binding, ribosomal small subunit binding, negative regulation of cell proliferation, ribonucleoprotein complex, intracellular protein transport, nucleic acid binding, response to stress, anti-apoptosis, protein oligomerization, ribosome assembly, centrosome, centrosome cycle, transcription coactivator activity, nucleus, protein heterodimerization activity, spindle pole centrosome, unfolded protein binding, protein homodimerization activity, positive regulation of NF-kappaB transcription factor activity, nucleoplasm, nucleocytoplasmic transport, signal transduction, RNA binding, nucleosome assembly, nucleolus, CenH3-containing nucleosome assembly at centromere, cell aging, ribosomal large subunit binding, Tat protein binding, interspecies interaction between organisms, NF-kappaB binding, negative regulation of centrosome duplication, regulation of endoribonuclease activity, regulation of endodeoxyribonuclease activity |
| InterPro Term |
Nucleoplasmin |
| InterPro ID |
IPR004301 |
| Ensembl Family |
ENSFM00500000270251 |
| Ensembl Family Description |
NUCLEOPHOSMIN NPM NUCLEOLAR PHOSPHOPROTEIN B23 NUCLEOLAR NO38 NUMATRIN |
| EMBL-Bank ID |
AY347529, BC107754, BT007011, X16934, DQ303464, AY740640, AY740634, AY740639, AY740636, AY740635, AY740638, AY740637, BC014349, M28699, BC009623, BC021668, BC002398, BC021983, AK290652, M31004, BC012566, M26697, AK000472, CH471062, BC050628, M23613, U89321, U89317, U89319, U89313, U89314, U89310, U89311, U89309, AB042278, BC008495, BC016824, BC016768, BC016716, BC003670, U04946, U41743, U41742, D45915, AB451361, J02590, AB451236, AC093246, AC091980 |
| RefSeq ID |
NP_001032827, NP_954654, NM_199185, NP_002511, NM_001037738, NM_002520 |
| Entrez Gene ID |
4869 |
| UniGene ID |
Hs.573436, Hs.600877, Hs.634598, Hs.727134, Hs.667403 |
| Ensembl Protein ID |
ENSP00000377408, ENSP00000429485, ENSP00000428647, ENSP00000428755, ENSP00000341168, ENSP00000296930 |
| UniProt Accession |
Q9NX34, Q9BTI9, P06748, Q9BYG9, E5RGW4, E5RI98 |
| Ensembl Gene ID |
ENSG00000181163 |
| Description |
nucleophosmin (nucleolar phosphoprotein B23, numatrin) [Source:HGNC Symbol;Acc:7910] |
| HGNC Symbol |
NPM1 |
| Ensembl Transcript ID |
ENST00000518587, ENST00000393820, ENST00000296930, ENST00000524204, ENST00000523339, ENST00000523622, ENST00000521710, ENST00000521672, ENST00000521260, ENST00000517671, ENST00000519955, ENST00000351986 |
| Gene-Disease Assocation |
LEUKEMIA, ACUTE MYELOID; AML |
| Design Element |
M23613_at, 88066_s_at, ENST00000521710, ENST00000393820, 221923_s_at, 200063_s_at, 221691_3p_x_at, ENST00000523622, ENST00000524204, ENST00000296930, g12803184_3p_a_at, Hs.9614.1.A1_3p_a_at, ENST00000521672, g13536990_3p_s_at, ENST00000517671, ENST00000519955, ENST00000523339, ENST00000518587, ENST00000521260, 38542_at, 221691_x_at, ENST00000351986, 78344_at |
| Search EB-eye |
ENSG00000181163
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