AEN
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Homo sapiens |
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AEN is differentially expressed in 208 experiments: 86 organism parts: kidney, lung, ... (84 more);, 141 disease states: normal, glioblastoma, ... (139 more);, 55 cell types 280 cell lines 28 compound treatments and 62 other conditions. |
| Synonyms |
ISG20L1, FLJ12484, FLJ12562 |
| Orthologs |
REX4
(Saccharomyces cerevisiae)
Aen
(Rattus norvegicus)
F6QDM2_CIOIN
(Ciona intestinalis)
AEN
(Bos taurus)
Aen
(Mus musculus)
AEN
(Gallus gallus)
isg20l2
(Danio rerio)
aen
(Xenopus laevis)
AL954306.1
(Danio rerio)
AEN
(Canis familiaris)
(Compare orthologs)
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| InterPro Term |
Exonuclease_RNaseT/DNA_pol3, Exonuclease |
| Gene Ontology ID |
GO:0003676, GO:0010212, GO:0016787, GO:0005622, GO:0042771, GO:0006915, GO:0005730, GO:0005634, GO:0005654, GO:0004527, GO:0006974 |
| Gene Ontology Term |
apoptosis, intracellular, nucleic acid binding, response to ionizing radiation, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, nucleus, hydrolase activity, nucleoplasm, response to DNA damage stimulus, exonuclease activity, nucleolus |
| InterPro ID |
IPR006055, IPR013520 |
| Ensembl Family |
ENSFM00500000270590 |
| Ensembl Family Description |
APOPTOSIS ENHANCING NUCLEASE EC_3.1.-.- INTERFERON STIMULATED 20 KDA EXONUCLEASE 1 |
| Description |
apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:25722] |
| RefSeq ID |
NM_022767, NP_073604 |
| EMBL-Bank ID |
AF318330, BC020988, BC014407, AK022546, CH471101, AC013489, AF327352, BC005164 |
| UniProt Accession |
Q8WYW8, Q8WTP8 |
| Entrez Gene ID |
64782 |
| Ensembl Protein ID |
ENSP00000331944, ENSP00000368533, ENSP00000453631 |
| Ensembl Gene ID |
ENSG00000181026 |
| HGNC Symbol |
AEN |
| Ensembl Transcript ID |
ENST00000379231, ENST00000332810, ENST00000559528, ENST00000560174, ENST00000557927, ENST00000558327, ENST00000557787 |
| UniGene ID |
Hs.436102 |
| Design Element |
51962_at, g12232442_3p_s_at, 219361_s_at, ENST00000559528, ENST00000379231, ENST00000557787, 63641_s_at, ENST00000557927, ENST00000560174, ENST00000558327, ENST00000332810 |
| Search EB-eye |
ENSG00000181026
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