PRF1
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Homo sapiens |
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PRF1 is differentially expressed in 240 experiments: 97 organism parts: bone marrow, lung, ... (95 more);, 189 disease states: normal, colorectal adenocarcinoma, ... (187 more);, 97 cell types 173 cell lines 28 compound treatments and 65 other conditions. |
| Synonyms |
P1, HPLH2, PFP |
| Orthologs |
PRF1 (5 of 6)
(Danio rerio)
PRF1 (3 of 6)
(Danio rerio)
PRF1 (2 of 6)
(Danio rerio)
PRF1 (4 of 6)
(Danio rerio)
Prf1
(Mus musculus)
PRF1 (6 of 6)
(Danio rerio)
PRF1 (1 of 6)
(Danio rerio)
PRF1
(Gallus gallus)
Q69GU5_BOVIN
(Bos taurus)
Prf1
(Rattus norvegicus)
ENSXETG00000012994
(Xenopus laevis)
prf1
(Xenopus laevis)
LOC100491518
(Xenopus laevis)
LOC100492973
(Xenopus laevis)
LOC100493300
(Xenopus laevis)
LOC100489487
(Xenopus laevis)
ENSXETG00000027891
(Xenopus laevis)
LOC100493140
(Xenopus laevis)
LOC100489324
(Xenopus laevis)
PRF1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
defense response to virus, plasma membrane, cytolysis, protein binding, apoptosis, protein homooligomerization, extracellular region, cytoplasmic membrane-bounded vesicle, endosome, integral to membrane, circadian rhythm, response to ethanol, cellular defense response, calcium ion binding, endosome lumen, immune response to tumor cell, cytolytic granule, defense response to tumor cell, wide pore channel activity |
| InterPro ID |
IPR000008, IPR018029, IPR020864 |
| Gene Ontology ID |
GO:0016021, GO:0016023, GO:0051260, GO:0007623, GO:0005509, GO:0005515, GO:0005576, GO:0006915, GO:0005886, GO:0005768, GO:0006968, GO:0019835, GO:0051607, GO:0045471, GO:0031904, GO:0002418, GO:0044194, GO:0022829, GO:0002357 |
| InterPro Term |
C2_Ca-dep, C2_membr_targeting, MACPF |
| Ensembl Family |
ENSFM00250000003207 |
| Ensembl Family Description |
PERFORIN 1 PRECURSOR P1 CYTOLYSIN LYMPHOCYTE PORE FORMING |
| EMBL-Bank ID |
AL355344, L40557, X13224, BC063043, BC047695, AB209604, CH471083, M31951, AK312754, M28393 |
| Ensembl Protein ID |
ENSP00000398568, ENSP00000362305, ENSP00000316746 |
| RefSeq ID |
NM_005041, NP_005032, NP_001076585, NM_001083116 |
| Description |
perforin 1 (pore forming protein) [Source:HGNC Symbol;Acc:9360] |
| Gene-Disease Assocation |
LYMPHOMA, NON-HODGKIN, FAMILIAL, HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 2; FHL2 |
| UniGene ID |
Hs.2200 |
| HGNC Symbol |
PRF1 |
| UniProt Accession |
P14222 |
| Ensembl Gene ID |
ENSG00000180644 |
| Entrez Gene ID |
5551 |
| Ensembl Transcript ID |
ENST00000318971, ENST00000373209, ENST00000473106, ENST00000441259 |
| Design Element |
ENST00000473106, ENST00000373209, 1553681_a_at, M31951_at, Hs2.2200.1.S1_3p_at, ENST00000441259, ENST00000318971, 1553681_3p_a_at, Hs.2200.0.S2_3p_at, 32904_at, 214617_at, Hs2.2200.1.S1_3p_s_at |
| Search EB-eye |
ENSG00000180644
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