CIITA
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Homo sapiens |
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CIITA is differentially expressed in 254 experiments: 135 organism parts: lung, bone marrow, ... (133 more);, 228 disease states: normal, control, ... (226 more);, 102 cell types 324 cell lines 27 compound treatments and 80 other conditions. |
| Synonyms |
C2TA, NLRA, MHC2TA |
| Orthologs |
CIITA
(Gallus gallus)
ciita
(Danio rerio)
CIITA
(Bos taurus)
Ciita
(Mus musculus)
Ciita
(Rattus norvegicus)
ciita
(Xenopus laevis)
CIITA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
response to antibiotic, negative regulation of transcription, DNA-dependent, protein binding, regulation of transcription, DNA-dependent, cytokine-mediated signaling pathway, ATP binding, positive regulation of transcription from RNA polymerase II promoter, transcription coactivator activity, nucleus, nucleotide binding, immune response, protein C-terminus binding, nucleoplasm, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, response to interferon-gamma, negative regulation of collagen biosynthetic process, positive regulation of MHC class II biosynthetic process, protein complex binding, activating transcription factor binding, interferon-gamma-mediated signaling pathway, positive regulation of MHC class I biosynthetic process, transcription regulatory region DNA binding |
| InterPro ID |
IPR001611, IPR007111, IPR003590, IPR008095 |
| InterPro Term |
NACHT_NTPase, Leu-rich_rpt_RNase_inh_sub-typ, Leu-rich_rpt, MHC_II_transact |
| Gene Ontology ID |
GO:0003713, GO:0008022, GO:0005524, GO:0005515, GO:0006955, GO:0005634, GO:0005654, GO:0000166, GO:0000122, GO:0006355, GO:0019221, GO:0045944, GO:0045892, GO:0045893, GO:0046677, GO:0033613, GO:0032403, GO:0032966, GO:0044212, GO:0045348, GO:0034341, GO:0060333, GO:0045345 |
| Ensembl Family Description |
MHC CLASS II TRANSACTIVATOR CIITA |
| Ensembl Family |
ENSFM00250000004537 |
| Description |
class II, major histocompatibility complex, transactivator [Source:HGNC Symbol;Acc:7067] |
| HGNC Symbol |
CIITA |
| EMBL-Bank ID |
EF064747, X74301, AC133065, CH471112, U18259 |
| UniProt Accession |
P33076, A0N0N9, E9PFE0, F2Z2G8, F5H2J4 |
| Entrez Gene ID |
4261 |
| Ensembl Protein ID |
ENSP00000373562, ENSP00000316328, ENSP00000371257, ENSP00000446228 |
| Gene-Disease Assocation |
BARE LYMPHOCYTE SYNDROME, TYPE II, MULTIPLE SCLEROSIS, SUSCEPTIBILITY TO; MS, RHEUMATOID ARTHRITIS; RA |
| UniGene ID |
Hs.716787, Hs.665026, Hs.701991 |
| RefSeq ID |
NP_000237, NM_000246 |
| Ensembl Gene ID |
ENSG00000179583 |
| Ensembl Transcript ID |
ENST00000537380, ENST00000388910, ENST00000381835, ENST00000324288 |
| Design Element |
210925_at, 35616_at, g4557748_3p_at, g1143159_3p_x_at, U18288_at, 211884_s_at, gnf1h11176_at, 205101_at, 41511_at, ENST00000537380, ENST00000324288, X74301_s_at, ENST00000388910, g1143159_3p_a_at, ENST00000381835, U18259_at, 77028_at, 83562_at, 88989_at, g836910_3p_at |
| Search EB-eye |
ENSG00000179583
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