GATA2
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Homo sapiens |
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GATA2 is differentially expressed in 306 experiments: 122 organism parts: placenta, prostate, ... (120 more);, 189 disease states: normal, lung adenocarcinoma, ... (187 more);, 109 cell types 418 cell lines 32 compound treatments and 82 other conditions. |
| Synonyms |
NFE1B |
| Orthologs |
gata2b
(Danio rerio)
GATA2_CHICK
(Gallus gallus)
Gata2
(Rattus norvegicus)
GATA2
(Bos taurus)
Gata2
(Mus musculus)
gata2a
(Danio rerio)
Q4H3F5_CIOIN
(Ciona intestinalis)
DAL80
(Saccharomyces cerevisiae)
GAT1
(Saccharomyces cerevisiae)
GZF3
(Saccharomyces cerevisiae)
GLN3
(Saccharomyces cerevisiae)
grn
(Drosophila melanogaster)
gata2
(Xenopus laevis)
GATA2
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003682, GO:0003677, GO:0008270, GO:0003700, GO:0007596, GO:0005515, GO:0006909, GO:0005634, GO:0005654, GO:0045746, GO:0000122, GO:0046872, GO:0006355, GO:0006351, GO:0001709, GO:0043234, GO:0045944, GO:0043565, GO:0021954, GO:0030154, GO:0030182, GO:0035065, GO:0035019, GO:0060216, GO:0048873, GO:0042472, GO:0048663, GO:0048469, GO:0050766, GO:0070742, GO:0045766, GO:0045638, GO:0045648, GO:0045654, GO:0045650, GO:0001892, GO:0045599, GO:0001655, GO:0021983, GO:0021533, GO:0060872, GO:0021514, GO:0000980, GO:0001158, GO:0070345, GO:2000178, GO:0001077, GO:0035854 |
| Gene Ontology Term |
neuron differentiation, DNA binding, protein binding, regulation of transcription, DNA-dependent, cell fate determination, protein complex, transcription, DNA-dependent, regulation of histone acetylation, metal ion binding, blood coagulation, transcription factor binding, cell differentiation, phagocytosis, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, negative regulation of Notch signaling pathway, nucleus, somatic stem cell maintenance, chromatin binding, central nervous system neuron development, nucleoplasm, negative regulation of transcription from RNA polymerase II promoter, zinc ion binding, pituitary gland development, positive regulation of erythrocyte differentiation, urogenital system development, definitive hemopoiesis, C2H2 zinc finger domain binding, negative regulation of myeloid cell differentiation, cell maturation, homeostasis of number of cells within a tissue, negative regulation of fat cell differentiation, cell differentiation in hindbrain, inner ear morphogenesis, neuron fate commitment, positive regulation of angiogenesis, negative regulation of macrophage differentiation, positive regulation of phagocytosis, positive regulation of megakaryocyte differentiation, embryonic placenta development, ventral spinal cord interneuron differentiation, semicircular canal development, sequence-specific DNA binding transcription factor activity, negative regulation of neural precursor cell proliferation, enhancer sequence-specific DNA binding, negative regulation of fat cell proliferation, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, eosinophil fate commitment, RNA polymerase II distal enhancer sequence-specific DNA binding |
| Ensembl Family Description |
TRANSCRIPTION FACTOR GATA GATA BINDING |
| InterPro ID |
IPR016374, IPR000679 |
| InterPro Term |
TF_GATA-1/2/3, Znf_GATA |
| Ensembl Family |
ENSFM00500000269911 |
| Ensembl Protein ID |
ENSP00000418132, ENSP00000400259, ENSP00000417074, ENSP00000419532, ENSP00000345681 |
| HGNC Symbol |
GATA2 |
| RefSeq ID |
NP_001139134, NP_001139133, NM_001145662, NM_001145661, NP_116027, NM_032638 |
| EMBL-Bank ID |
BC051342, BC051272, BC015613, BC015577, CH471052, BC002557, AK314826, BT006671, AC080005, M68891, BC018988, M77810 |
| Entrez Gene ID |
2624 |
| Description |
GATA binding protein 2 [Source:HGNC Symbol;Acc:4171] |
| UniProt Accession |
C9J965, P23769 |
| UniGene ID |
Hs.709024, Hs.367725 |
| Ensembl Gene ID |
ENSG00000179348 |
| Ensembl Transcript ID |
ENST00000487848, ENST00000492608, ENST00000430265, ENST00000341105, ENST00000498200, ENST00000489987 |
| Gene-Disease Assocation |
DENDRITIC CELL, MONOCYTE, B LYMPHOCYTE, AND NATURAL KILLER LYMPHOCYTE |
| Design Element |
ENST00000489987, Hs.760.1.S2_3p_at, 210358_x_at, ENST00000492608, ENST00000430265, ENST00000487848, g4503926_3p_a_at, M68891_at, ENST00000498200, 1072_g_at, 37194_at, 210358_3p_x_at, g12803464_3p_a_at, 203_at, g12803464_3p_x_at, 209710_at, ENST00000341105 |
| Search EB-eye |
ENSG00000179348
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