GRB2
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Homo sapiens |
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GRB2 is differentially expressed in 255 experiments: 93 organism parts: pancreas, spleen, ... (91 more);, 164 disease states: normal, control, ... (162 more);, 65 cell types 311 cell lines 30 compound treatments and 67 other conditions. |
| Synonyms |
NCKAP2 |
| Orthologs |
GRB2 (2 of 2)
(Danio rerio)
grb2
(Danio rerio)
Q3T0F9_BOVIN
(Bos taurus)
Grb2
(Rattus norvegicus)
ENSCING00000005670
(Ciona intestinalis)
Grb2
(Mus musculus)
A3R0S3_CHICK
(Gallus gallus)
drk
(Drosophila melanogaster)
grb2
(Xenopus laevis)
GRB2
(Canis familiaris)
(Compare orthologs)
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| Ensembl Family Description |
GROWTH FACTOR RECEPTOR BOUND 2 ADAPTER GRB2 SH2/SH3 ADAPTER GRB2 |
| Gene Ontology Term |
cytosol, vesicle membrane, negative regulation of epidermal growth factor receptor signaling pathway, protein binding, cytoplasm, epidermal growth factor receptor signaling pathway, protein complex, membrane, Golgi apparatus, insulin receptor signaling pathway, insulin receptor substrate binding, cell-cell signaling, blood coagulation, protein domain specific binding, receptor internalization, ephrin receptor binding, epidermal growth factor receptor binding, fibroblast growth factor receptor signaling pathway, cell differentiation, regulation of MAPKKK cascade, Ras protein signal transduction, axon guidance, aging, SH3/SH2 adaptor activity, phosphoprotein binding, leukocyte migration, branching involved in embryonic placenta morphogenesis, anatomical structure formation involved in morphogenesis, phosphotyrosine binding, interspecies interaction between organisms, nerve growth factor receptor signaling pathway, T cell costimulation, protein heterooligomerization, positive regulation of reactive oxygen species metabolic process, signal transduction in response to DNA damage, cellular response to ionizing radiation, cell junction assembly |
| InterPro Term |
SH2, SH3_domain, SH3_2, p67phox, SH3_3 |
| Gene Ontology ID |
GO:0008286, GO:0016020, GO:0007173, GO:0007265, GO:0007267, GO:0008543, GO:0007411, GO:0007568, GO:0051219, GO:0007596, GO:0005515, GO:0012506, GO:0005737, GO:0005829, GO:0005794, GO:0005154, GO:0005070, GO:0019904, GO:0031623, GO:0046875, GO:0043234, GO:0042059, GO:0043560, GO:0043408, GO:0030154, GO:0048011, GO:0060670, GO:0051291, GO:0048646, GO:0042770, GO:0031295, GO:0001784, GO:0044419, GO:0050900, GO:0071479, GO:2000379, GO:0034329 |
| InterPro ID |
IPR000108, IPR001452, IPR011511, IPR000980, IPR013247 |
| Ensembl Family |
ENSFM00500000270097 |
| Ensembl Protein ID |
ENSP00000317360, ENSP00000339007, ENSP00000376346, ENSP00000376345, ENSP00000376347 |
| RefSeq ID |
NP_987102, NM_203506, NP_002077, NM_002086 |
| UniGene ID |
Hs.444356 |
| EMBL-Bank ID |
M96995, AF063614, AF063615, AF063616, AF063617, AF063618, X62852, CH471099, EU332843, AK315565, BC000631, CR541942, L29511, AF498925, AC011933 |
| UniProt Accession |
P62993, B0LPF3 |
| Entrez Gene ID |
2885 |
| Ensembl Gene ID |
ENSG00000177885 |
| HGNC Symbol |
GRB2 |
| Description |
growth factor receptor-bound protein 2 [Source:HGNC Symbol;Acc:4566] |
| Ensembl Transcript ID |
ENST00000316804, ENST00000316615, ENST00000462266, ENST00000392562, ENST00000392563, ENST00000392564 |
| Design Element |
215075_s_at, ENST00000316804, g12005510_3p_at, gnf1h00446_at, 46217_at, ENST00000316615, M96995_s_at, Hs.296381.1.A1_3p_a_at, ENST00000392562, ENST00000392563, 33855_at, ENST00000392564, ENST00000462266, 1565_s_at, 223049_at |
| Search EB-eye |
ENSG00000177885
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