JUN
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Homo sapiens |
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JUN is differentially expressed in 360 experiments: 145 organism parts: bone marrow, lung, ... (143 more);, 215 disease states: normal, glioblastoma, ... (213 more);, 111 cell types 478 cell lines 64 compound treatments and 80 other conditions. |
| Synonyms |
AP-1, c-Jun |
| Orthologs |
F7B9Z5_CIOIN
(Ciona intestinalis)
E1C766_CHICK
(Gallus gallus)
Q08DH1_BOVIN
(Bos taurus)
jun
(Danio rerio)
Jun
(Mus musculus)
Jun
(Rattus norvegicus)
Jra
(Drosophila melanogaster)
jun
(Xenopus laevis)
JUN
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
angiogenesis, Toll signaling pathway, cytosol, response to hydrogen peroxide, transcriptional repressor complex, DNA binding, negative regulation of transcription, DNA-dependent, negative regulation of DNA binding, protein binding, cellular process, regulation of transcription, DNA-dependent, nuclear chromatin, double-stranded DNA binding, negative regulation of cell proliferation, innate immune response, transcription, DNA-dependent, positive regulation of cell proliferation, negative regulation of apoptosis, nuclear chromosome, transforming growth factor beta receptor signaling pathway, stress-activated MAPK cascade, transcription from RNA polymerase II promoter, positive regulation of apoptosis, transcription factor binding, learning, sequence-specific DNA binding, protein dimerization activity, positive regulation of transcription from RNA polymerase II promoter, response to cAMP, transcription coactivator activity, regulation of cell cycle, nucleus, response to lipopolysaccharide, aging, positive regulation of DNA replication, transcription factor complex, response to drug, protein homodimerization activity, circadian rhythm, nucleoplasm, response to radiation, positive regulation of transcription, DNA-dependent, response to mechanical stimulus, Rho GTPase activator activity, negative regulation of neuron apoptosis, outflow tract morphogenesis, toll-like receptor 4 signaling pathway, response to cytokine stimulus, leading edge cell differentiation, toll-like receptor signaling pathway, positive regulation by host of viral transcription, membrane depolarization, axon regeneration, negative regulation by host of viral transcription, cellular response to calcium ion, toll-like receptor 3 signaling pathway, positive regulation of fibroblast proliferation, cellular response to potassium ion starvation, release of cytochrome c from mitochondria, monocyte differentiation, liver development, response to organic substance, positive regulation of endothelial cell proliferation, toll-like receptor 2 signaling pathway, positive regulation of neuron apoptosis, positive regulation of monocyte differentiation, positive regulation of smooth muscle cell proliferation, MyD88-dependent toll-like receptor signaling pathway, R-SMAD binding, SMAD protein signal transduction, microglial cell activation, sequence-specific DNA binding transcription factor activity, MyD88-independent toll-like receptor signaling pathway, regulation of sequence-specific DNA binding transcription factor activity, SMAD protein import into nucleus, negative regulation of protein autophosphorylation, response to organic cyclic compound, transcription regulatory region DNA binding, positive regulation of Rho GTPase activity, toll-like receptor 1 signaling pathway, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity |
| Gene Ontology ID |
GO:0008134, GO:0003677, GO:0003690, GO:0008285, GO:0008284, GO:0009987, GO:0003713, GO:0003700, GO:0003705, GO:0008063, GO:0007179, GO:0009612, GO:0051403, GO:0007568, GO:0042493, GO:0007612, GO:0007623, GO:0051090, GO:0042542, GO:0042803, GO:0005515, GO:0005634, GO:0005654, GO:0005667, GO:0005829, GO:0005100, GO:0032496, GO:0043065, GO:0043066, GO:0000790, GO:0045740, GO:0051726, GO:0043392, GO:0006355, GO:0006351, GO:0006366, GO:0046983, GO:0000228, GO:0045944, GO:0043524, GO:0001525, GO:0043565, GO:0045892, GO:0045893, GO:0051591, GO:0009314, GO:0045087, GO:0017053, GO:0034097, GO:0060395, GO:0034142, GO:0034138, GO:0034134, GO:0007184, GO:0010033, GO:0051365, GO:0031953, GO:0002755, GO:0048661, GO:0043922, GO:0043923, GO:0003151, GO:0014070, GO:0002224, GO:0048146, GO:0001938, GO:0031103, GO:0001774, GO:0051899, GO:0045657, GO:0001889, GO:0001836, GO:0043525, GO:0044212, GO:0070412, GO:0071277, GO:0030224, GO:0035026, GO:0002756, GO:0032321, GO:0034130 |
| InterPro Term |
bZIP_1, bZIP_2, Leuzip_Jun, JNK, TF_bZIP |
| InterPro ID |
IPR011700, IPR011616, IPR005643, IPR002112, IPR004827 |
| Ensembl Family |
ENSFM00250000001645 |
| Ensembl Family Description |
TRANSCRIPTION FACTOR AP 1 PROTO ONCOGENE C JUN |
| EMBL-Bank ID |
BC006175, BC068522, BC009874, BT019759, BC002646, J04111, AY217548, AL136985 |
| UniGene ID |
Hs.525704, Hs.696684 |
| Description |
jun proto-oncogene [Source:HGNC Symbol;Acc:6204] |
| UniProt Accession |
P05412 |
| Ensembl Gene ID |
ENSG00000177606 |
| Entrez Gene ID |
3725 |
| Ensembl Protein ID |
ENSP00000360266 |
| RefSeq ID |
NP_002219, NM_002228 |
| HGNC Symbol |
JUN |
| Ensembl Transcript ID |
ENST00000371222 |
| Design Element |
32583_at, 201465_s_at, 201466_s_at, ENST00000371222, g12803622_3p_s_at, 201464_x_at, g7710122_3p_a_at, Hs.78465.0.S2_3p_a_at, 89913_s_at |
| Search EB-eye |
ENSG00000177606
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