SMAD2
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Homo sapiens |
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SMAD2 is differentially expressed in 359 experiments: 151 organism parts: liver, ovary, ... (149 more);, 242 disease states: normal, acute myeloid leukemia, ... (240 more);, 111 cell types 502 cell lines 56 compound treatments and 80 other conditions. |
| Synonyms |
JV18-1, MADH2, MADR2 |
| Orthologs |
SMAD2
(Gallus gallus)
Q08DE0_BOVIN
(Bos taurus)
SMAD2
(Gallus gallus)
smad2
(Danio rerio)
Smad2
(Rattus norvegicus)
Smad2
(Mus musculus)
ENSCING00000006188
(Ciona intestinalis)
Smox
(Drosophila melanogaster)
smad2
(Xenopus laevis)
SMAD2
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
zygotic specification of dorsal/ventral axis, cytosol, pattern specification process, mesoderm formation, DNA binding, negative regulation of transcription, DNA-dependent, protein binding, regulation of transcription, DNA-dependent, cytoplasm, double-stranded DNA binding, intracellular, negative regulation of cell proliferation, protein complex, transcription, DNA-dependent, developmental growth, embryonic foregut morphogenesis, transforming growth factor beta receptor signaling pathway, regulation of transforming growth factor beta receptor signaling pathway, organ growth, transcription factor binding, endoderm development, positive regulation of transcription from RNA polymerase II promoter, transforming growth factor beta receptor binding, nucleus, heart development, transcription factor complex, post-embryonic development, cell fate commitment, chromatin binding, SMAD binding, nucleoplasm, gastrulation, positive regulation of transcription, DNA-dependent, embryonic pattern specification, ubiquitin protein ligase binding, positive regulation of epithelial to mesenchymal transition, regulation of binding, phosphatase binding, in utero embryonic development, response to cholesterol, pericardium development, co-SMAD binding, activin responsive factor complex, pancreas development, SMAD protein complex assembly, transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity, lung development, insulin secretion, palate development, embryonic cranial skeleton morphogenesis, response to glucose stimulus, paraxial mesoderm morphogenesis, ureteric bud development, R-SMAD binding, common-partner SMAD protein phosphorylation, type I transforming growth factor beta receptor binding, I-SMAD binding, sequence-specific DNA binding transcription factor activity, protein phosphorylation, activating transcription factor binding, intracellular signal transduction, primary miRNA processing, SMAD protein complex, anterior/posterior pattern specification |
| Gene Ontology ID |
GO:0008134, GO:0009880, GO:0003682, GO:0003677, GO:0003690, GO:0009952, GO:0008285, GO:0003700, GO:0007179, GO:0009791, GO:0007369, GO:0007389, GO:0007352, GO:0007492, GO:0007507, GO:0048617, GO:0048589, GO:0005622, GO:0005515, GO:0005737, GO:0005634, GO:0005654, GO:0005667, GO:0005829, GO:0046332, GO:0005160, GO:0031053, GO:0006468, GO:0031625, GO:0006355, GO:0006351, GO:0001707, GO:0043234, GO:0045944, GO:0045892, GO:0045893, GO:0033613, GO:0045165, GO:0017015, GO:0035265, GO:0010718, GO:0060021, GO:0060039, GO:0007182, GO:0007183, GO:0009749, GO:0048701, GO:0030618, GO:0051098, GO:0048340, GO:0032444, GO:0019902, GO:0031016, GO:0070723, GO:0001701, GO:0001657, GO:0030073, GO:0070412, GO:0070411, GO:0070410, GO:0030324, GO:0034713, GO:0035556, GO:0071141 |
| InterPro Term |
MAD_homology1_Dwarfin-type, SMAD_dom_Dwarfin-type, MAD_homology_MH1, Interferon_reg_factor-3 |
| InterPro ID |
IPR001132, IPR013019, IPR003619, IPR019471 |
| Ensembl Family |
ENSFM00250000000238 |
| Ensembl Family Description |
MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG MAD HOMOLOG MOTHERS AGAINST DPP HOMOLOG SMAD FAMILY MEMBER SMAD |
| RefSeq ID |
NM_001135937, NM_005901, NP_005892, NP_001003652, NP_001129409, NM_001003652 |
| EMBL-Bank ID |
BC025699, BT007422, U65019, BC014840, CH471096, AK312963, U59911, U68018, U78728, U78729, U78727, U78733, U78732, U78731, U78730, AF027964 |
| Ensembl Protein ID |
ENSP00000349282, ENSP00000384449, ENSP00000262160 |
| UniProt Accession |
Q15796, Q53XR6 |
| UniGene ID |
Hs.705764, Hs.12253, Hs.625113, Hs.702196, Hs.629015, Hs.617511 |
| Entrez Gene ID |
4087 |
| Description |
SMAD family member 2 [Source:HGNC Symbol;Acc:6768] |
| HGNC Symbol |
SMAD2 |
| Ensembl Gene ID |
ENSG00000175387 |
| Ensembl Transcript ID |
ENST00000262160, ENST00000356825, ENST00000402690 |
| Design Element |
Hs.12253.0.A1_3p_at, g1575529_3p_a_at, 203075_at, 50764_at, 226563_at, 1453_at, Hs.204129.0.A1_3p_at, 57493_at, ENST00000262160, 90267_at, 239271_at, 1928_s_at, g5174510_3p_a_at, Hs.82483.0.A3_3p_at, 70271_at, 203077_s_at, 53730_at, 203076_s_at, ENST00000356825, ENST00000402690, U68018_at, Hs.110741.0.A1_3p_at, 235598_at |
| Search EB-eye |
ENSG00000175387
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