DDIT3
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Homo sapiens |
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DDIT3 is differentially expressed in 262 experiments: 92 organism parts: prostate, uterus, ... (90 more);, 116 disease states: normal, glioblastoma, ... (114 more);, 77 cell types 233 cell lines 32 compound treatments and 61 other conditions. |
| Synonyms |
CHOP10, GADD153, CHOP |
| Orthologs |
Ddit3
(Mus musculus)
DDIT3_BOVIN
(Bos taurus)
Ddit3
(Rattus norvegicus)
ddit3
(Xenopus laevis)
DDIT3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003677, GO:0003714, GO:0003700, GO:0007049, GO:0007050, GO:0007584, GO:0007568, GO:0042493, GO:0042542, GO:0042789, GO:0005515, GO:0043620, GO:0005737, GO:0005634, GO:0030968, GO:0005789, GO:0006979, GO:0006974, GO:0042981, GO:0043065, GO:0006355, GO:0006351, GO:0046983, GO:0043565, GO:0045893, GO:0043433, GO:0034976, GO:0045454, GO:0048568, GO:0006983, GO:0090090, GO:0001975, GO:0032792, GO:2000016 |
| Gene Ontology Term |
response to hydrogen peroxide, response to oxidative stress, DNA binding, protein binding, regulation of transcription, DNA-dependent, cytoplasm, transcription, DNA-dependent, cell redox homeostasis, transcription corepressor activity, cell cycle arrest, positive regulation of apoptosis, transcription factor binding, mRNA transcription from RNA polymerase II promoter, sequence-specific DNA binding, response to nutrient, cell cycle, protein dimerization activity, nucleus, aging, response to drug, response to DNA damage stimulus, endoplasmic reticulum unfolded protein response, endoplasmic reticulum membrane, response to endoplasmic reticulum stress, positive regulation of transcription, DNA-dependent, regulation of apoptosis, embryonic organ development, negative regulation of CREB transcription factor activity, ER overload response, response to amphetamine, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of determination of dorsal identity, sequence-specific DNA binding transcription factor activity, regulation of DNA-dependent transcription in response to stress, negative regulation of sequence-specific DNA binding transcription factor activity |
| InterPro Term |
bZIP_2, TF_bZIP, DNA_damage_induc_transcript_3 |
| InterPro ID |
IPR011700, IPR004827, IPR016670 |
| Ensembl Family |
ENSFM00250000007884 |
| EMBL-Bank ID |
AK316581, S40706, AC022506, S62138, CH471054, BT006691, BC003637, AY880949 |
| UniProt Accession |
P35638, Q53YD1, F8VS99, F8W133 |
| Entrez Gene ID |
1649 |
| RefSeq ID |
NM_001195054, NM_001195053, NM_001195056, NM_001195055, NM_001195057, NM_004083, NP_001181986, NP_001181982, NP_001181983, NP_001181984, NP_001181985, NP_004074 |
| Ensembl Protein ID |
ENSP00000340671, ENSP00000448665, ENSP00000447803, ENSP00000447503, ENSP00000447188 |
| HGNC Symbol |
DDIT3 |
| Description |
DNA-damage-inducible transcript 3 [Source:HGNC Symbol;Acc:2726] |
| Ensembl Gene ID |
ENSG00000175197 |
| Ensembl Family Description |
DNA DAMAGE INDUCIBLE TRANSCRIPT 3 DDIT 3 C/EBP HOMOLOGOUS CHOP C/EBP HOMOLOGOUS 10 CHOP 10 GROWTH ARREST AND DNA DAMAGE INDUCIBLE GADD153 |
| UniGene ID |
Hs.731299, Hs.505777 |
| Ensembl Transcript ID |
ENST00000551116, ENST00000547303, ENST00000547526, ENST00000550148, ENST00000346473, ENST00000552740 |
| Gene-Disease Assocation |
MYXOID LIPOSARCOMA |
| Design Element |
1842_at, 39420_at, ENST00000551116, ENST00000552740, ENST00000547526, ENST00000550148, g13177717_3p_at, 209383_at, ENST00000547303, ENST00000346473 |
| Search EB-eye |
ENSG00000175197
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