MGMT
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Homo sapiens |
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MGMT is differentially expressed in 243 experiments: 82 organism parts: liver, brain, ... (80 more);, 156 disease states: normal, glioblastoma, ... (154 more);, 65 cell types 406 cell lines 32 compound treatments and 69 other conditions. |
| Orthologs |
Mgmt
(Mus musculus)
Mgmt
(Rattus norvegicus)
MGMT
(Gallus gallus)
MGT1
(Saccharomyces cerevisiae)
MGMT
(Danio rerio)
agt
(Drosophila melanogaster)
mgmt
(Xenopus laevis)
MGMT_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008168, GO:0003677, GO:0003824, GO:0003908, GO:0009636, GO:0042493, GO:0016740, GO:0005509, GO:0005634, GO:0005654, GO:0006974, GO:0006306, GO:0006307, GO:0006281, GO:0045471, GO:0032259, GO:0060644, GO:0060548, GO:0014070, GO:0045739, GO:0043281, GO:0006266, GO:0051593, GO:0071407, GO:0034599, GO:0009008, GO:0071479 |
| Gene Ontology Term |
DNA methylation, DNA binding, methylated-DNA-[protein]-cysteine S-methyltransferase activity, DNA repair, response to toxin, DNA dealkylation involved in DNA repair, methyltransferase activity, nucleus, methylation, response to drug, transferase activity, nucleoplasm, response to DNA damage stimulus, response to ethanol, catalytic activity, calcium ion binding, cellular response to oxidative stress, DNA-methyltransferase activity, positive regulation of DNA repair, mammary gland epithelial cell differentiation, negative regulation of cell death, response to folic acid, DNA ligation, response to organic cyclic compound, cellular response to organic cyclic compound, cellular response to ionizing radiation, regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| InterPro ID |
IPR014048, IPR008332 |
| Ensembl Family Description |
METHYLATED DNA CYSTEINE METHYLTRANSFERASE EC_2.1.1.63 6 O METHYLGUANINE DNA METHYLTRANSFERASE MGMT O 6 METHYLGUANINE DNA ALKYLTRANSFERASE |
| Ensembl Family |
ENSFM00500000274452 |
| InterPro Term |
MethylG_MeTrfase, MethylDNA_cys_MeTrfase_DNA-bd |
| EMBL-Bank ID |
AL355531, M60761, X54228, AK293593, M29971, CH471066, M31767, BC000824, AL157832, BT006714, S52068 |
| UniProt Accession |
P16455, Q6LDD1, B4DEE8 |
| HGNC Symbol |
MGMT |
| Entrez Gene ID |
4255 |
| Description |
O-6-methylguanine-DNA methyltransferase [Source:HGNC Symbol;Acc:7059] |
| UniGene ID |
Hs.501522 |
| Ensembl Gene ID |
ENSG00000170430 |
| RefSeq ID |
NP_002403, NM_002412 |
| Ensembl Protein ID |
ENSP00000302111 |
| Ensembl Transcript ID |
ENST00000462672, ENST00000482547, ENST00000482653, ENST00000306010 |
| Design Element |
2051_at, ENST00000482653, M29971_at, ENST00000482547, g4505176_3p_at, ENST00000306010, 2052_g_at, 204880_at, ENST00000462672 |
| Search EB-eye |
ENSG00000170430
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