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E2F6
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Homo sapiens
E2F6 is differentially expressed in 86 experiments: 44 organism parts: placenta, blood, ... (42 more);, 125 disease states: normal, acute promyelocytic leukemia, ... (123 more);, 29 cell types 92 cell lines 10 compound treatments and 39 other conditions.
Synonyms E2F-6
Orthologs E1C979_CHICK (Gallus gallus)   E2F6 (Danio rerio)   E2f6 (Mus musculus)   D4A9U7_RAT (Rattus norvegicus)   E2f (Drosophila melanogaster)   E2F6_BOVIN (Bos taurus)   E2F6 (Canis familiaris)   (Compare orthologs)
Gene Ontology Term DNA binding, regulation of transcription, DNA-dependent, transcription, DNA-dependent, transcription corepressor activity, cell cycle, nucleus, transcription factor complex, negative regulation of transcription from RNA polymerase II promoter, MLL1 complex, sequence-specific DNA binding transcription factor activity, regulation of transcription involved in G1/S phase of mitotic cell cycle
InterPro Term E2F_TDP
UniProt Accession Q6Q9Z5, Q53YM3, Q2Z196, Q2Z197, O75461, B7Z1I8, F8WEZ5, F8WC40
Search EB-eye ENSG00000169016
Show more properties
Experimental Factors
Organism part

studied in E-AFMX-5, E-GEOD-803, E-TABM-125, E-MTAB-24, E-MTAB-25, ... (11 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-5258, E-GEOD-1880, E-GEOD-22639, E-GEOD-18005, E-GEOD-2450, ... (14 experiments)

Factor Value U/D Experiments
SW480
2
E-GEOD-18005, E-GEOD-2509
sk-n-mc cell line, lentivirus treated
1
E-MTAB-62
sk-n-mc cell line; lentivirus treated
1
E-MTAB-62
Hep-2
1
E-MTAB-62
KELLY
1
E-MTAB-62
LU165
1
E-MTAB-62
86 more value(s).


Cell type

studied in E-AFMX-5, E-MTAB-24, E-GEOD-19397, E-MTAB-25, E-GEOD-3920, ... (13 experiments)

Factor Value U/D Experiments
721 B lymphoblast
1
1
E-AFMX-5
epidermoid
1
E-GEOD-19397
NK cell
1
E-GEOD-3982
hematopoietic progenitor cells
1
E-MEXP-70
leydig cell
1
E-MTAB-25
macrophage
1
E-GEOD-3982
23 more value(s).


Disease state

studied in E-GEOD-3307, E-GEOD-1880, E-GEOD-2712, E-GEOD-2549, E-GEOD-6919, ... (19 experiments)

Factor Value U/D Experiments
malignant melanoma
2
E-GEOD-3189, E-MTAB-62
hepatocellular adenoma
1
E-MTAB-62
chondromyxoid fibroma
1
E-MTAB-62
atopic mild asthmatics
1
E-MTAB-62
acute lymphocytic leukemia
1
E-GEOD-1880
nephrosclerosis
1
E-GEOD-20602
119 more value(s).


Compound treatment

studied in E-MEXP-1269, E-GEOD-5258, E-GEOD-412, E-GEOD-2803, E-GEOD-5824, ... (8 experiments)

Factor Value U/D Experiments
none
1
3
E-GEOD-5824, E-GEOD-412, E-GEOD-995, E-GEOD-2803
dimethyl sulfoxide
3
1
E-GEOD-5824
rapamycin
1
E-GEOD-5824
17beta-estradiol
3
1
E-GEOD-4006
control
17
1
E-GEOD-4006
trichostatin A
1
E-MEXP-1269
4 more value(s).


BioSourceProvider

studied in E-GEOD-19466, E-GEOD-19480

Factor Value U/D Experiments
Coriell Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=NA18499
1
1
E-GEOD-19480
Coriell Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=NA19209
1
E-GEOD-19480
Coriell Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=NA19239
1
E-GEOD-19480
Coriell Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=NA19108
1
E-GEOD-19480
Coriell Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=NA19131
1
E-GEOD-19480
Coriell Cell Repositories http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM12891
1
E-GEOD-19466
7 more value(s).


Blood/non-blood meta-groups
studied in E-MTAB-62

Cancer site
studied in E-GEOD-4271

Cellular component
studied in E-GEOD-1400

Chromosomal aberration
studied in E-TABM-125, E-GEOD-1729

Clinical history
studied in E-TABM-125, E-GEOD-1725

Clinical treatment
studied in E-GEOD-6532

development stage
studied in E-GEOD-22601

Developmental stage
studied in E-GEOD-4667, E-MTAB-62

Disease staging
studied in E-GEOD-2509, E-TABM-147

double amplification
studied in E-GEOD-22601

Environmental stress
studied in E-GEOD-1518

Estrogen receptor status
studied in E-GEOD-6532

Genotype
studied in E-GEOD-3494, E-GEOD-22593

369 groups
studied in E-MTAB-62

4 groups from blood to incompletely diff
studied in E-MTAB-62

96 groups
studied in E-MTAB-62

Growth condition
studied in E-GEOD-6432

Her2 fish
studied in E-GEOD-20194, E-GEOD-16716

Individual
studied in E-MTAB-197, E-GEOD-1926, E-GEOD-6919, E-GEOD-2322, E-GEOD-3284, ... (13 experiments)

15 meta groups
studied in E-MTAB-62

4 meta groups
studied in E-MTAB-62

6 meta groups
studied in E-MTAB-62

organ
studied in E-GEOD-24283

Organism
studied in E-AFMX-1, E-GEOD-426

Population
studied in E-GEOD-4922, E-GEOD-4342

Progesterone receptor status
studied in E-GEOD-6532

Protocol type
studied in E-GEOD-3254

RNAi
studied in E-MEXP-101

sampleID
studied in E-GEOD-24283

Sampling time point
studied in E-MEXP-70

Strain or line
studied in E-TABM-125

Subtype
studied in E-GEOD-24283

targeted_cell_type
studied in E-MEXP-70

Test result
studied in E-GEOD-1926

Treatments comments
studied in E-GEOD-20194, E-GEOD-16716

Tumor grading
studied in E-GEOD-4922

Tumor size
studied in E-GEOD-4922

Vehicle
studied in E-GEOD-5258

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM