STAT3
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Homo sapiens |
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STAT3 is differentially expressed in 347 experiments: 133 organism parts: liver, adipose tissue, ... (131 more);, 201 disease states: normal, glioblastoma, ... (199 more);, 107 cell types 473 cell lines 66 compound treatments and 87 other conditions. |
| Synonyms |
APRF |
| Orthologs |
STAT3
(Bos taurus)
Stat3
(Rattus norvegicus)
stat3
(Danio rerio)
Stat3
(Mus musculus)
STAT3
(Gallus gallus)
stat3.1
(Xenopus laevis)
STAT3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003677, GO:0008283, GO:0003700, GO:0007165, GO:0007259, GO:0007399, GO:0042493, GO:0042593, GO:0004715, GO:0005509, GO:0005515, GO:0004871, GO:0006928, GO:0006953, GO:0005737, GO:0005634, GO:0005654, GO:0005886, GO:0005829, GO:0006606, GO:0040014, GO:0019901, GO:0045747, GO:0000122, GO:0001754, GO:0006355, GO:0006357, GO:0006351, GO:0006366, GO:0019221, GO:0046983, GO:0045944, GO:0043565, GO:0045893, GO:0045471, GO:0034097, GO:0048011, GO:0060397, GO:0060396, GO:0003706, GO:0060019, GO:0010033, GO:0048708, GO:0014070, GO:0042755, GO:0019953, GO:0032870, GO:0044419, GO:0044212, GO:0001659, GO:0043434, GO:0070102, GO:0032355, GO:0035259, GO:0031730 |
| Gene Ontology Term |
regulation of multicellular organism growth, cytosol, plasma membrane, DNA binding, protein binding, regulation of transcription, DNA-dependent, cytokine-mediated signaling pathway, cytoplasm, cellular component movement, cell proliferation, protein import into nucleus, transcription, DNA-dependent, acute-phase response, positive regulation of Notch signaling pathway, transcription from RNA polymerase II promoter, glucose homeostasis, signal transducer activity, transcription factor binding, sequence-specific DNA binding, protein dimerization activity, positive regulation of transcription from RNA polymerase II promoter, protein kinase binding, nucleus, eye photoreceptor cell differentiation, response to drug, JAK-STAT cascade, nervous system development, nucleoplasm, negative regulation of transcription from RNA polymerase II promoter, regulation of transcription from RNA polymerase II promoter, response to ethanol, non-membrane spanning protein tyrosine kinase activity, signal transduction, positive regulation of transcription, DNA-dependent, calcium ion binding, glucocorticoid receptor binding, response to cytokine stimulus, eating behavior, astrocyte differentiation, temperature homeostasis, ligand-regulated transcription factor activity, interspecies interaction between organisms, radial glial cell differentiation, response to peptide hormone stimulus, growth hormone receptor signaling pathway, response to estradiol stimulus, interleukin-6-mediated signaling pathway, sexual reproduction, response to organic substance, nerve growth factor receptor signaling pathway, cellular response to hormone stimulus, JAK-STAT cascade involved in growth hormone signaling pathway, sequence-specific DNA binding transcription factor activity, response to organic cyclic compound, CCR5 chemokine receptor binding, transcription regulatory region DNA binding |
| InterPro Term |
SH2, STAT_TF_alpha, STAT_TF_prot_interaction, STAT_TF_DNA-bd |
| Ensembl Family Description |
SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION |
| InterPro ID |
IPR000980, IPR013799, IPR013800, IPR013801 |
| Ensembl Family |
ENSFM00500000269705 |
| Ensembl Gene ID |
ENSG00000168610 |
| RefSeq ID |
NP_644805, NM_139276, NM_003150, NP_003141, NM_213662, NP_998827 |
| EMBL-Bank ID |
BC014482, AY572796, AF029311, BC000627, L29277, AJ012463 |
| Gene-Disease Assocation |
HYPER-IgE RECURRENT INFECTION SYNDROME, AUTOSOMAL DOMINANT |
| Entrez Gene ID |
6774 |
| Ensembl Protein ID |
ENSP00000373923, ENSP00000384943, ENSP00000264657 |
| HGNC Symbol |
STAT3 |
| UniGene ID |
Hs.463059 |
| Description |
signal transducer and activator of transcription 3 (acute-phase response factor) [Source:HGNC Symbol;Acc:11364] |
| UniProt Accession |
P40763 |
| Ensembl Transcript ID |
ENST00000491272, ENST00000264657, ENST00000471989, ENST00000404395, ENST00000478276, ENST00000462269, ENST00000462286, ENST00000389272, ENST00000498330 |
| Design Element |
Hs.288544.0.S1_3p_at, ENST00000404395, 225289_at, g12653684_3p_a_at, 39708_at, ENST00000491272, ENST00000471989, L29277_at, 289_at, 208991_at, ENST00000462269, 208992_s_at, ENST00000389272, ENST00000264657, ENST00000498330, 63330_at, ENST00000462286, ENST00000478276 |
| Search EB-eye |
ENSG00000168610
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