BTRC
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Homo sapiens |
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BTRC is differentially expressed in 294 experiments: 145 organism parts: lung, heart, ... (143 more);, 223 disease states: normal, acute myeloid leukemia, ... (221 more);, 92 cell types 390 cell lines 44 compound treatments and 84 other conditions. |
| Synonyms |
Fwd1, betaTrCP, beta-TrCP1, bTrCP1, bTrCP, FBXW1A |
| Orthologs |
BTRC
(Bos taurus)
Q86SD3_CIOIN
(Ciona intestinalis)
Btrc
(Rattus norvegicus)
BTRC
(Gallus gallus)
Btrc
(Mus musculus)
slmb
(Drosophila melanogaster)
MET30
(Saccharomyces cerevisiae)
ENSXETG00000021199
(Xenopus laevis)
BTRC
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, ligase activity, negative regulation of transcription, DNA-dependent, protein binding, cytoplasm, protein catabolic process, beta-catenin binding, protein ubiquitination, mitotic cell cycle, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, SCF ubiquitin ligase complex, Wnt receptor signaling pathway, regulation of cell cycle, nucleus, protein polyubiquitination, ubiquitin-protein ligase activity, regulation of I-kappaB kinase/NF-kappaB cascade, signal transduction, positive regulation of transcription, DNA-dependent, positive regulation of proteolysis, ubiquitin-dependent protein catabolic process, mammary gland epithelial cell proliferation, viral reproduction, protein destabilization, protein phosphorylated amino acid binding, interspecies interaction between organisms, regulation of proteasomal protein catabolic process, branching involved in mammary gland duct morphogenesis, positive regulation of circadian rhythm, protein dephosphorylation, positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, cellular response to organic cyclic compound, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| InterPro Term |
WD40_repeat_dom, WD40_repeat, F-box_dom_cyclin-like, WD40_repeat_2, G-protein_beta_WD-40_rep, Beta-TrCP_D, WD40_repeat_subgr |
| Gene Ontology ID |
GO:0016055, GO:0008013, GO:0016567, GO:0007165, GO:0016874, GO:0005515, GO:0004842, GO:0005737, GO:0005634, GO:0005829, GO:0006511, GO:0043122, GO:0006470, GO:0031145, GO:0051726, GO:0000278, GO:0000209, GO:0045862, GO:0045892, GO:0045893, GO:0030163, GO:0019005, GO:0060444, GO:0016032, GO:0061136, GO:0042753, GO:0031648, GO:0044419, GO:0033598, GO:0045309, GO:0071407, GO:0051437, GO:0051439 |
| InterPro ID |
IPR001680, IPR017986, IPR019781, IPR019782, IPR001810, IPR020472, IPR021977 |
| Ensembl Family Description |
F BOX/WD REPEAT CONTAINING F BOX AND WD REPEATS BETA |
| Ensembl Family |
ENSFM00500000270002 |
| UniProt Accession |
Q9Y297, Q5T1W7, Q5W141, Q68DS0, B7Z3H4, Q86WI4 |
| EMBL-Bank ID |
AK313353, AK295870, BC027994, AL445463, AL627424, CR749295, AL133387, CH471066, Y14153, AF101784, AF129530, AY207476, GU727631 |
| Ensembl Gene ID |
ENSG00000166167 |
| RefSeq ID |
NM_033637, NM_003939, NP_003930, NP_378663 |
| UniGene ID |
Hs.643802 |
| Entrez Gene ID |
8945 |
| Ensembl Protein ID |
ENSP00000385339, ENSP00000377088, ENSP00000359202, ENSP00000359206, ENSP00000437608 |
| Description |
beta-transducin repeat containing [Source:HGNC Symbol;Acc:1144] |
| HGNC Symbol |
BTRC |
| Ensembl Transcript ID |
ENST00000493877, ENST00000370183, ENST00000370187, ENST00000465182, ENST00000408038, ENST00000393441, ENST00000539411, ENST00000475200 |
| Design Element |
ENST00000539411, 45239_at, ENST00000370187, 60838_at, 216091_s_at, ENST00000393441, ENST00000493877, 85189_at, g13623214_3p_s_at, 224471_s_at, ENST00000475200, 39305_at, ENST00000370183, ENST00000408038, ENST00000465182, Hs.226434.1.S1_3p_a_at, Hs.170212.0.A1_3p_at, 39303_at, 204901_at, 1563620_at, 222374_at, Hs.226434.0.S2_3p_at, 39304_g_at |
| Search EB-eye |
ENSG00000166167
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