JAK1
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Homo sapiens |
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JAK1 is differentially expressed in 308 experiments: 127 organism parts: liver, ovary, ... (125 more);, 190 disease states: normal, prostate carcinoma, ... (188 more);, 115 cell types 376 cell lines 53 compound treatments and 80 other conditions. |
| Synonyms |
JAK1B, JAK1A, JTK3 |
| Orthologs |
Q9YI47_CHICK
(Gallus gallus)
Jak1
(Mus musculus)
jak1
(Danio rerio)
Jak1
(Rattus norvegicus)
Q4H3A3_CIOIN
(Ciona intestinalis)
F1MQR0_BOVIN
(Bos taurus)
PR2
(Drosophila melanogaster)
jak1
(Xenopus laevis)
Q6QHH1_CANFA
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR000299, IPR001245, IPR017442, IPR000719, IPR019749, IPR000980, IPR020635, IPR016251, IPR020776 |
| Gene Ontology Term |
endomembrane system, cytosol, response to antibiotic, protein binding, cytoskeleton, cytokine-mediated signaling pathway, cytoplasm, membrane, peptidyl-tyrosine phosphorylation, protein tyrosine kinase activity, ATP binding, nucleus, nucleotide binding, protein serine/threonine kinase activity, non-membrane spanning protein tyrosine kinase activity, protein kinase activity, intracellular protein kinase cascade, regulation of interferon-gamma-mediated signaling pathway, regulation of type I interferon-mediated signaling pathway, growth hormone receptor binding, enzyme linked receptor protein signaling pathway, protein phosphorylation, intracellular signal transduction, interferon-gamma-mediated signaling pathway, type I interferon-mediated signaling pathway |
| InterPro Term |
SH2, Prot_kinase_cat_dom, Band_41_domain, FERM_domain, Tyr_kinase_non-rcpt_Jak/Tyk2, Tyr_kinase_non-rcpt_Jak1, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Gene Ontology ID |
GO:0016020, GO:0007243, GO:0004713, GO:0004715, GO:0005524, GO:0005515, GO:0012505, GO:0005737, GO:0005634, GO:0005856, GO:0005829, GO:0004672, GO:0004674, GO:0006468, GO:0000166, GO:0018108, GO:0019221, GO:0046677, GO:0060338, GO:0060334, GO:0007167, GO:0005131, GO:0035556, GO:0060333, GO:0060337 |
| Ensembl Family |
ENSFM00250000000777 |
| Ensembl Family Description |
TYROSINE KINASE EC_2.7.10.2 JANUS KINASE JAK |
| EMBL-Bank ID |
AB209057, BC132729, AC093427, CH471059, M64174 |
| Ensembl Gene ID |
ENSG00000162434 |
| Description |
Janus kinase 1 [Source:HGNC Symbol;Acc:6190] |
| Entrez Gene ID |
3716 |
| UniProt Accession |
P23458 |
| HGNC Symbol |
JAK1 |
| RefSeq ID |
NP_002218, NM_002227 |
| Ensembl Protein ID |
ENSP00000343204 |
| UniGene ID |
Hs.610395 |
| Ensembl Transcript ID |
ENST00000342505, ENST00000465376, ENST00000471473, ENST00000467764, ENST00000494904, ENST00000481702 |
| Design Element |
ENST00000342505, 34877_at, 1457_at, 1552611_a_at, ENST00000465376, Hs2.50651.1.S1_3p_s_at, ENST00000471473, M64174_at, ENST00000467764, 41594_at, 201648_at, Hs2.50651.1.S2_3p_s_at, ENST00000494904, 1552610_a_at, ENST00000481702, Hs.50651.0.S2_3p_at |
| Search EB-eye |
ENSG00000162434
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