SHC1
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Homo sapiens |
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SHC1 is differentially expressed in 299 experiments: 172 organism parts: lung, liver, ... (170 more);, 245 disease states: normal, control, ... (243 more);, 93 cell types 516 cell lines 42 compound treatments and 80 other conditions. |
| Synonyms |
p66, SHC |
| Orthologs |
SHC1_BOVIN
(Bos taurus)
SHC1
(Gallus gallus)
SHC1
(Danio rerio)
Shc1
(Rattus norvegicus)
ENSCING00000006400
(Ciona intestinalis)
Shc1
(Mus musculus)
Shc
(Drosophila melanogaster)
shc1
(Xenopus laevis)
SHC1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
angiogenesis, neuron differentiation, cytosol, response to hydrogen peroxide, insulin-like growth factor receptor binding, plasma membrane, actin cytoskeleton reorganization, protein binding, cytoplasm, cell-cell adhesion, epidermal growth factor receptor signaling pathway, response to toxin, positive regulation of cell proliferation, MAPKKK cascade, insulin receptor binding, mitochondrial matrix, insulin receptor signaling pathway, blood coagulation, response to hypoxia, phospholipid binding, ephrin receptor binding, endosome membrane, epidermal growth factor receptor binding, fibroblast growth factor receptor signaling pathway, activation of MAPK activity, actin cytoskeleton organization, Ras protein signal transduction, neuron projection development, nucleus, heart development, aging, positive regulation of DNA replication, phosphoprotein binding, regulation of growth, mitochondrion, leukocyte migration, response to nicotine, organ regeneration, phosphotyrosine binding, response to insulin stimulus, nerve growth factor receptor signaling pathway, Shc-EGFR complex, protein complex binding, positive regulation of smooth muscle cell proliferation, response to glucocorticoid stimulus, positive regulation of vasoconstriction, intracellular signal transduction, transmembrane receptor protein tyrosine kinase adaptor activity, response to organic cyclic compound, regulation of epidermal growth factor-activated receptor activity |
| InterPro Term |
SH2, PID_domain, PTyr_interaction_dom |
| Gene Ontology ID |
GO:0008286, GO:0008284, GO:0007176, GO:0007173, GO:0009636, GO:0010008, GO:0007265, GO:0016337, GO:0008543, GO:0007568, GO:0051219, GO:0007596, GO:0007507, GO:0042542, GO:0005515, GO:0005543, GO:0005737, GO:0005739, GO:0005759, GO:0005634, GO:0005886, GO:0005829, GO:0005158, GO:0005159, GO:0005154, GO:0040008, GO:0031175, GO:0000165, GO:0045740, GO:0000187, GO:0046875, GO:0001525, GO:0031532, GO:0001666, GO:0030182, GO:0030036, GO:0048011, GO:0051384, GO:0048661, GO:0014070, GO:0032403, GO:0005068, GO:0031100, GO:0032868, GO:0001784, GO:0045907, GO:0070435, GO:0050900, GO:0035094, GO:0035556 |
| Ensembl Family Description |
SHC TRANSFORMING SRC HOMOLOGY 2 DOMAIN CONTAINING TRANSFORMING SH2 DOMAIN |
| InterPro ID |
IPR000980, IPR006019, IPR006020 |
| Ensembl Family |
ENSFM00250000001102 |
| UniGene ID |
Hs.433795 |
| Ensembl Protein ID |
ENSP00000401303, ENSP00000396162, ENSP00000398441, ENSP00000398864, ENSP00000357428, ENSP00000357426, ENSP00000357438, ENSP00000357435, ENSP00000357434, ENSP00000357430, ENSP00000396333, ENSP00000404908 |
| EMBL-Bank ID |
BC033925, Y09847, CH471121, BC014158, AK292143, AL451085, U73377, X68148, AK296786, AF455141, AK315842, AB451379, AB451255 |
| RefSeq ID |
NM_003029, NM_183001, NP_003020, NP_001123512, NP_001123513, NP_892113, NM_001130041, NM_001130040, NM_001202859, NP_001189788 |
| Entrez Gene ID |
6464 |
| HGNC Symbol |
SHC1 |
| UniProt Accession |
P29353, Q5T182, Q5T181, Q5T189, Q5T188, Q5T187, Q8NFT1, Q8NFT0, B4DL02, E9PFM5 |
| Description |
SHC (Src homology 2 domain containing) transforming protein 1 [Source:HGNC Symbol;Acc:10840] |
| Ensembl Gene ID |
ENSG00000160691 |
| Ensembl Transcript ID |
ENST00000366442, ENST00000444664, ENST00000444179, ENST00000414115, ENST00000490667, ENST00000412170, ENST00000448116, ENST00000368441, ENST00000368449, ENST00000368445, ENST00000368443, ENST00000368453, ENST00000368450 |
| Design Element |
ENST00000444664, ENST00000412170, ENST00000490667, U73377_at, ENST00000368449, ENST00000368443, ENST00000368445, ENST00000368453, ENST00000368441, ENST00000368450, ENST00000448116, ENST00000366442, ENST00000414115, ENST00000444179, 214853_s_at, 38118_at, 201469_s_at, Hs.81972.0.A1_3p_a_at, Hs.81972.1.A1_3p_a_at |
| Search EB-eye |
ENSG00000160691
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