GHRL
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Homo sapiens |
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GHRL is differentially expressed in 66 experiments: 28 organism parts: stomach cardiac, stomach fundus, ... (26 more);, 31 disease states: normal, breast carcinoma, ... (29 more);, 21 cell types 131 cell lines 14 compound treatments and 31 other conditions. |
| Synonyms |
ghrelin, obestatin, MTLRP |
| Orthologs |
GHRL
(Gallus gallus)
GHRL_BOVIN
(Bos taurus)
Ghrl
(Mus musculus)
Ghrl
(Rattus norvegicus)
GHRL_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008154, GO:0008343, GO:0060079, GO:0007186, GO:0007204, GO:0016358, GO:0009755, GO:0009725, GO:0030424, GO:0005615, GO:0005576, GO:0006916, GO:0005737, GO:0005788, GO:0005179, GO:0040018, GO:0043066, GO:0051965, GO:0000187, GO:0042127, GO:0001664, GO:0006006, GO:0030141, GO:0030296, GO:0032095, GO:0060399, GO:0016608, GO:0016525, GO:0060124, GO:0051216, GO:0042322, GO:0042536, GO:0046010, GO:0061098, GO:0043627, GO:0040013, GO:0001937, GO:0050728, GO:0032691, GO:0031768, GO:0051464, GO:0051461, GO:0046697, GO:0001696, GO:0046676, GO:0030252, GO:0045409, GO:0032100, GO:0032024, GO:0032097, GO:0043400 |
| Gene Ontology Term |
protein tyrosine kinase activator activity, stored secretory granule, glucose metabolic process, elevation of cytosolic calcium ion concentration, regulation of excitatory postsynaptic membrane potential, axon, cytoplasm, regulation of cell proliferation, extracellular space, actin polymerization or depolymerization, negative regulation of apoptosis, hormone-mediated signaling pathway, G-protein coupled receptor protein signaling pathway, extracellular region, positive regulation of multicellular organism growth, G-protein-coupled receptor binding, anti-apoptosis, activation of MAPK activity, hormone activity, regulation of response to food, adult feeding behavior, response to hormone stimulus, dendrite development, endoplasmic reticulum lumen, negative regulation of tumor necrosis factor biosynthetic process, positive regulation of growth hormone secretion, negative regulation of interleukin-6 biosynthetic process, positive regulation of growth hormone receptor signaling pathway, positive regulation of response to food, negative regulation of circadian sleep/wake cycle, REM sleep, negative regulation of angiogenesis, growth hormone-releasing hormone activity, decidualization, gastric acid secretion, positive regulation of circadian sleep/wake cycle, non-REM sleep, negative regulation of interleukin-1 beta production, negative regulation of insulin secretion, response to estrogen stimulus, positive regulation of insulin secretion, negative regulation of inflammatory response, positive regulation of appetite, cartilage development, negative regulation of locomotion, positive regulation of cortisol secretion, growth hormone secretion, ghrelin receptor binding, positive regulation of protein tyrosine kinase activity, negative regulation of endothelial cell proliferation, cortisol secretion, positive regulation of corticotropin secretion, positive regulation of synapse assembly |
| InterPro Term |
Preproghrelin, Motilin_assoc, Motilin_ghrelin |
| InterPro ID |
IPR005441, IPR006738, IPR006737 |
| Ensembl Gene ID |
ENSG00000157017 |
| Ensembl Protein ID |
ENSP00000391406, ENSP00000414819, ENSP00000388145, ENSP00000403725, ENSP00000416768, ENSP00000335074, ENSP00000405031, ENSP00000405464, ENSP00000394923, ENSP00000287656, ENSP00000389192, ENSP00000415521, ENSP00000399922 |
| EMBL-Bank ID |
BC025791, AF296558, AC022384, AB029434, EU072084, EU072083, EU072087, EU072085, EU072086, AJ252278, CH471055, DQ864724, DQ864725, AY184207, AB035700, AY359053, AY701846, EF549557, EF549569, EF549571, EF549572, EF549573, EF549575, EF549574 |
| RefSeq ID |
NP_001128416, NP_001128417, NP_001128418, NP_001128413, NP_057446, NM_016362, NM_001134946, NM_001134945, NM_001134944, NM_001134941, NR_024132, NR_024134, NR_024135, NR_024137, NR_024138 |
| UniGene ID |
Hs.590080 |
| Ensembl Family Description |
APPETITE REGULATING HORMONE PRECURSOR GROWTH HORMONE SECRETAGOGUE GROWTH HORMONE RELEASING PEPTIDE MOTILIN RELATED PEPTIDE [CONTAINS OBESTATIN] |
| UniProt Accession |
Q9UBU3, Q86YP8, A8DN24, Q5Y392, A2T3X3, A2T3X2, E7ESW0 |
| Description |
ghrelin/obestatin prepropeptide [Source:HGNC Symbol;Acc:18129] |
| Gene-Disease Assocation |
OBESITY |
| Entrez Gene ID |
51738 |
| Ensembl Family |
ENSFM00600000922569 |
| HGNC Symbol |
GHRL |
| Ensembl Transcript ID |
ENST00000446937, ENST00000476283, ENST00000457360, ENST00000475759, ENST00000449238, ENST00000449554, ENST00000422159, ENST00000430179, ENST00000429122, ENST00000437422, ENST00000481287, ENST00000335542, ENST00000425479, ENST00000287656, ENST00000439975, ENST00000450603, ENST00000491589 |
| Design Element |
ENST00000446937, ENST00000449554, ENST00000476283, ENST00000437422, ENST00000430179, ENST00000335542, ENST00000475759, ENST00000457360, ENST00000449238, ENST00000422159, ENST00000481287, 223862_at, ENST00000425479, 80871_at, ENST00000287656, ENST00000491589, ENST00000429122, g11691901_3p_at, ENST00000439975, ENST00000450603 |
| Search EB-eye |
ENSG00000157017
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