BUB1B
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Homo sapiens |
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BUB1B is differentially expressed in 304 experiments: 110 organism parts: bone marrow, testis, ... (108 more);, 236 disease states: normal, colon carcinoma, ... (234 more);, 92 cell types 314 cell lines 34 compound treatments and 72 other conditions. |
| Synonyms |
MAD3L, Bub1A, BUBR1, SSK1 |
| Orthologs |
BUB1B
(Gallus gallus)
BUB1B
(Danio rerio)
Bub1b
(Mus musculus)
BUB1B
(Bos taurus)
ENSCING00000017219
(Ciona intestinalis)
BUB1
(Saccharomyces cerevisiae)
MAD3
(Saccharomyces cerevisiae)
Bub1b
(Rattus norvegicus)
BubR1
(Drosophila melanogaster)
Bub1
(Drosophila melanogaster)
bub1b
(Xenopus laevis)
BUB1B
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0048015, GO:0008283, GO:0007049, GO:0007051, GO:0007094, GO:0007093, GO:0007067, GO:0051233, GO:0051301, GO:0016772, GO:0048471, GO:0000087, GO:0000075, GO:0005524, GO:0005515, GO:0006915, GO:0005737, GO:0005680, GO:0005694, GO:0005634, GO:0005856, GO:0005829, GO:0005815, GO:0004672, GO:0004674, GO:0000777, GO:0000776, GO:0000940, GO:0006468, GO:0031145, GO:0000166, GO:0000278, GO:0000236, GO:0034501, GO:0007091, GO:0051436, GO:0051439 |
| Gene Ontology Term |
cytosol, spindle midzone, anaphase-promoting complex, cell division, M phase of mitotic cell cycle, protein binding, apoptosis, cytoskeleton, kinetochore, cytoplasm, cell proliferation, protein localization to kinetochore, mitotic cell cycle, condensed chromosome kinetochore, spindle organization, anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, mitotic prometaphase, ATP binding, cell cycle, transferase activity, transferring phosphorus-containing groups, microtubule organizing center, nucleus, mitotic cell cycle checkpoint, mitosis, nucleotide binding, protein serine/threonine kinase activity, perinuclear region of cytoplasm, chromosome, cell cycle checkpoint, mitotic cell cycle spindle assembly checkpoint, protein kinase activity, mitotic metaphase/anaphase transition, negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle, condensed chromosome outer kinetochore, protein phosphorylation, phosphatidylinositol-mediated signaling, regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| InterPro ID |
IPR017442, IPR013212 |
| InterPro Term |
Mad3_BUB1_I, Se/Thr_kinase-like_dom |
| Ensembl Family Description |
MITOTIC CHECKPOINT SERINE/THREONINE KINASE BUB1 BETA EC_2.7.11.1 MAD3/BUB1 RELATED KINASE MITOTIC CHECKPOINT KINASE MAD3L |
| Ensembl Family |
ENSFM00250000005223 |
| EMBL-Bank ID |
AC025429, AF046918, AF053306, AF068760, AF046079, AF107297, AK312709, AF310214, AF310210, AF310211, AF310212, AF310213, AF310208, AF310209, AF310206, AF310207, AF310200, AF310201, AF310204, AF310205, AF310202, AF310203, AB208782, AF310199, AF310197, AF310198, AF310195, AF310196, AF310193, AF310194, AF310192, AK296795, BC018739, AF035933, AK296984 |
| Ensembl Protein ID |
ENSP00000398470, ENSP00000409013, ENSP00000287598, ENSP00000452903, ENSP00000453643, ENSP00000453861 |
| HGNC Symbol |
BUB1B |
| RefSeq ID |
NP_001202, NM_001211 |
| Ensembl Gene ID |
ENSG00000156970 |
| UniProt Accession |
C9JLW5, O60566 |
| Description |
budding uninhibited by benzimidazoles 1 homolog beta (yeast) [Source:HGNC Symbol;Acc:1149] |
| Entrez Gene ID |
701 |
| Gene-Disease Assocation |
MOSAIC VARIEGATED ANEUPLOIDY SYNDROME 1; MVA1, COLORECTAL CANCER; CRC, PREMATURE CHROMATID SEPARATION TRAIT; PCS |
| Ensembl Transcript ID |
ENST00000442874, ENST00000412359, ENST00000287598, ENST00000559414, ENST00000559461, ENST00000559772, ENST00000559733, ENST00000560120, ENST00000558715, ENST00000557848, ENST00000558151, ENST00000558972 |
| Design Element |
ENST00000559772, ENST00000442874, ENST00000559733, ENST00000559414, ENST00000558151, g5729749_3p_at, ENST00000558715, ENST00000558972, ENST00000412359, ENST00000559461, ENST00000560120, ENST00000287598, 203755_at, ENST00000557848, 73477_at, 35699_at |
| Search EB-eye |
ENSG00000156970
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