AIFM1
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Homo sapiens |
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AIFM1 is differentially expressed in 254 experiments: 104 organism parts: kidney, liver, ... (102 more);, 196 disease states: normal, adenocarcinoma, ... (194 more);, 75 cell types 352 cell lines 31 compound treatments and 65 other conditions. |
| Synonyms |
AIF, PDCD8 |
| Orthologs |
Aifm1
(Rattus norvegicus)
Aifm1
(Mus musculus)
AIFM1
(Bos taurus)
AIFM1
(Gallus gallus)
ENSCING00000005922
(Ciona intestinalis)
pdcd8
(Danio rerio)
AIF
(Drosophila melanogaster)
aifm1
(Xenopus laevis)
AIFM1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, oxidoreductase activity, DNA binding, protein binding, mitochondrial inner membrane, cytoplasm, DNA damage response, signal transduction resulting in induction of apoptosis, cell redox homeostasis, membrane, mitochondrial intermembrane space, activation of caspase activity, soluble fraction, microsome, nucleus, electron carrier activity, perinuclear region of cytoplasm, DNA fragmentation involved in apoptotic nuclear change, neuron apoptosis, mitochondrion, apoptosis in response to endoplasmic reticulum stress, oxidation-reduction process, flavin adenine dinucleotide binding |
| Gene Ontology ID |
GO:0003677, GO:0016020, GO:0008630, GO:0016491, GO:0051402, GO:0048471, GO:0005625, GO:0005515, GO:0006919, GO:0005737, GO:0005739, GO:0005758, GO:0005743, GO:0005634, GO:0005829, GO:0005792, GO:0055114, GO:0050660, GO:0006309, GO:0045454, GO:0009055, GO:0070059 |
| InterPro ID |
IPR001327, IPR013027, IPR023753 |
| InterPro Term |
FAD_pyr_nucl-diS_OxRdtase, Pyr_nucl-diS_OxRdtase_FAD/NAD, Pyr_OxRdtase_NAD-bd_dom |
| Ensembl Family |
ENSFM00250000002966 |
| Ensembl Family Description |
APOPTOSIS INDUCING FACTOR 1 MITOCHONDRIAL PRECURSOR EC 1 PROGRAMMED CELL DEATH 8 |
| Entrez Gene ID |
9131 |
| UniProt Accession |
O95831, Q1L6K4, Q1L6K6, Q2QKE4, E9PMQ8, E9PRR0, E9PMA0 |
| UniGene ID |
Hs.424932, Hs.56294 |
| RefSeq ID |
NM_145812, NM_145813, NM_004208, NP_001124318, NP_001124319, NP_665811, NP_665812, NM_001130846, NM_001130847, NP_004199 |
| Description |
apoptosis-inducing factor, mitochondrion-associated, 1 [Source:HGNC Symbol;Acc:8768] |
| EMBL-Bank ID |
CR457379, AF100928, AF131759, AK314446, CH471059, CH471107, AL139234, BC111065, DQ016496, DQ016498, DQ016500, AL049704, AL049703, BC139738 |
| Ensembl Protein ID |
ENSP00000315122, ENSP00000405879, ENSP00000402535, ENSP00000287295, ENSP00000316320, ENSP00000431222, ENSP00000446113, ENSP00000435955, ENSP00000432998 |
| Ensembl Gene ID |
ENSG00000156709 |
| HGNC Symbol |
AIFM1 |
| Ensembl Transcript ID |
ENST00000460436, ENST00000287295, ENST00000440263, ENST00000527892, ENST00000416073, ENST00000346424, ENST00000535724, ENST00000529877, ENST00000533719, ENST00000319908 |
| Gene-Disease Assocation |
COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 6; COXPD6 |
| Design Element |
ENST00000416073, ENST00000346424, ENST00000287295, 32212_at, ENST00000460436, ENST00000319908, ENST00000535724, ENST00000440263, ENST00000529877, ENST00000533719, ENST00000527892, g4757731_3p_a_at, 205512_s_at |
| Search EB-eye |
ENSG00000156709
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