NR3C2
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Homo sapiens |
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NR3C2 is differentially expressed in 245 experiments: 111 organism parts: amygdala, bone marrow, ... (109 more);, 184 disease states: normal, colon carcinoma, ... (182 more);, 82 cell types 275 cell lines 18 compound treatments and 61 other conditions. |
| Synonyms |
MLR, MR |
| Orthologs |
MCR_CHICK
(Gallus gallus)
Nr3c2
(Mus musculus)
nr3c2
(Danio rerio)
NR3C2
(Bos taurus)
Nr3c2
(Rattus norvegicus)
nr3c2
(Xenopus laevis)
Q3HTT9_CANFA
(Canis familiaris)
ENSCAFG00000007813
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0003690, GO:0008270, GO:0003700, GO:0003707, GO:0042562, GO:0005496, GO:0042803, GO:0005515, GO:0004872, GO:0005737, GO:0005634, GO:0046872, GO:0042127, GO:0006355, GO:0006351, GO:0046982, GO:0043565, GO:0031959, GO:0007588, GO:0006883, GO:0043401, GO:0017082 |
| InterPro ID |
IPR001628, IPR000536 |
| Gene Ontology Term |
protein binding, regulation of transcription, DNA-dependent, cytoplasm, double-stranded DNA binding, regulation of cell proliferation, hormone binding, transcription, DNA-dependent, metal ion binding, sequence-specific DNA binding, nucleus, protein heterodimerization activity, steroid binding, receptor activity, protein homodimerization activity, steroid hormone receptor activity, zinc ion binding, mineralocorticoid receptor signaling pathway, steroid hormone mediated signaling pathway, excretion, mineralocorticoid receptor activity, cellular sodium ion homeostasis, sequence-specific DNA binding transcription factor activity |
| InterPro Term |
Nucl_hrmn_rcpt_lig-bd_core, Znf_hrmn_rcpt |
| Ensembl Family Description |
RECEPTOR NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER |
| Ensembl Protein ID |
ENSP00000350815, ENSP00000347441, ENSP00000341390, ENSP00000343907, ENSP00000421481, ENSP00000423510, ENSP00000444458 |
| EMBL-Bank ID |
EU326312, AC069272, AC093881, AC106889, AC093678, AC104691, FJ515829, AK304318 |
| RefSeq ID |
NM_000901, NM_001166104, NP_001159576, NP_000892 |
| UniGene ID |
Hs.606257, Hs.163924 |
| UniProt Accession |
Q4W5E8, B0ZBF7, B0ZBF6, B0ZBF8, B0ZBF5, P08235, B4E2K8, F5GZH0 |
| HGNC Symbol |
NR3C2 |
| Entrez Gene ID |
4306 |
| Ensembl Gene ID |
ENSG00000151623 |
| Description |
nuclear receptor subfamily 3, group C, member 2 [Source:HGNC Symbol;Acc:7979] |
| Gene-Disease Assocation |
HYPERTENSION, EARLY-ONSET, AUTOSOMAL DOMINANT, WITH SEVERE EXACERBATION, PSEUDOHYPOALDOSTERONISM, TYPE I, AUTOSOMAL DOMINANT; PHA1A |
| Ensembl Family |
ENSFM00640001103036 |
| Ensembl Transcript ID |
ENST00000503313, ENST00000503174, ENST00000342437, ENST00000512865, ENST00000358102, ENST00000544252, ENST00000504753, ENST00000511528, ENST00000344721, ENST00000355292 |
| Design Element |
ENST00000355292, ENST00000512865, ENST00000344721, ENST00000503174, M16801_at, ENST00000358102, ENST00000503313, ENST00000544252, ENST00000342437, 205259_at, ENST00000504753, g4505198_3p_at, 33249_at, ENST00000511528 |
| Search EB-eye |
ENSG00000151623
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