FOXO1
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Homo sapiens |
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FOXO1 is differentially expressed in 350 experiments: 146 organism parts: bone marrow, cerebellum, ... (144 more);, 251 disease states: normal, control, ... (249 more);, 123 cell types 409 cell lines 45 compound treatments and 73 other conditions. |
| Synonyms |
FKHR, FKH1, FOXO1A |
| Orthologs |
foxo1b
(Danio rerio)
Foxo1
(Mus musculus)
foxo1a
(Danio rerio)
foxo
(Drosophila melanogaster)
FOXO1A
(Gallus gallus)
FOXO1
(Bos taurus)
Foxo1
(Rattus norvegicus)
FOXO1 (1 of 3)
(Danio rerio)
ENSCING00000016777
(Ciona intestinalis)
ENSCING00000016781
(Ciona intestinalis)
FOXO1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0009888, GO:0048015, GO:0003677, GO:0003690, GO:0008286, GO:0008301, GO:0003700, GO:0003705, GO:0009790, GO:0008543, GO:0007389, GO:0051090, GO:0005515, GO:0006916, GO:0005737, GO:0005634, GO:0005654, GO:0005667, GO:0005829, GO:0006974, GO:0019901, GO:0042127, GO:0006355, GO:0006357, GO:0006351, GO:0045944, GO:0043565, GO:0045893, GO:0048011, GO:0048513, GO:0031018, GO:0045722, GO:0032873, GO:0001568 |
| Gene Ontology Term |
cytosol, pattern specification process, embryo development, DNA binding, protein binding, regulation of transcription, DNA-dependent, cytoplasm, double-stranded DNA binding, regulation of cell proliferation, transcription, DNA-dependent, DNA bending activity, insulin receptor signaling pathway, anti-apoptosis, fibroblast growth factor receptor signaling pathway, transcription factor binding, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, tissue development, protein kinase binding, nucleus, transcription factor complex, nucleoplasm, response to DNA damage stimulus, regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, blood vessel development, negative regulation of stress-activated MAPK cascade, positive regulation of gluconeogenesis, organ development, nerve growth factor receptor signaling pathway, endocrine pancreas development, sequence-specific DNA binding transcription factor activity, phosphatidylinositol-mediated signaling, regulation of sequence-specific DNA binding transcription factor activity, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity |
| InterPro ID |
IPR001766 |
| Ensembl Family Description |
FORKHEAD BOX O |
| InterPro Term |
TF_fork_head |
| Ensembl Family |
ENSFM00250000000963 |
| UniGene ID |
Hs.370666, Hs.711044 |
| EMBL-Bank ID |
BT007455, AL355132, AF032885, BC021981, AL133318, U02310, BC070065 |
| Entrez Gene ID |
2308 |
| Ensembl Protein ID |
ENSP00000368880 |
| RefSeq ID |
NP_002006, NM_002015 |
| Ensembl Gene ID |
ENSG00000150907 |
| UniProt Accession |
Q12778 |
| Description |
forkhead box O1 [Source:HGNC Symbol;Acc:3819] |
| HGNC Symbol |
FOXO1 |
| Ensembl Transcript ID |
ENST00000379561, ENST00000473775 |
| Gene-Disease Assocation |
RHABDOMYOSARCOMA 2; RMS2 |
| Design Element |
202724_s_at, g9257221_3p_a_at, U36922_at, 202723_s_at, 40570_at, ENST00000379561, Hs.170133.0.A1_3p_s_at, ENST00000473775, U02310_at |
| Search EB-eye |
ENSG00000150907
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