HMGA2
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Homo sapiens |
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HMGA2 is differentially expressed in 290 experiments: 121 organism parts: lung, blood, ... (119 more);, 213 disease states: normal, control, ... (211 more);, 94 cell types 535 cell lines 37 compound treatments and 76 other conditions. |
| Synonyms |
BABL, LIPO, HMGIC |
| Orthologs |
HMGA2
(Gallus gallus)
hmga2
(Danio rerio)
HMGA2
(Bos taurus)
Hmga2
(Mus musculus)
Hmga2
(Rattus norvegicus)
hmga2
(Xenopus laevis)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003680, GO:0003677, GO:0010628, GO:0008284, GO:0008301, GO:0003906, GO:0007049, GO:0007067, GO:0007283, GO:0007275, GO:0008584, GO:0048863, GO:0051301, GO:0005515, GO:0005634, GO:0046332, GO:0040018, GO:0040008, GO:0043065, GO:0043066, GO:0000785, GO:0000122, GO:0006325, GO:0043392, GO:0006355, GO:0001837, GO:0000228, GO:0006284, GO:0045944, GO:0031492, GO:0031507, GO:0045892, GO:0045893, GO:0030261, GO:0035019, GO:0060612, GO:0007095, GO:0009615, GO:0060123, GO:0048712, GO:0048762, GO:0048333, GO:0043922, GO:0042769, GO:0002062, GO:0004677, GO:0070742, GO:0032993, GO:0051575, GO:0021983, GO:0035497, GO:0021846, GO:0045444, GO:0030325, GO:0071158, GO:0003131, GO:2000036, GO:0010564, GO:0045869, GO:2000679, GO:0060613, GO:0000988, GO:0001078, GO:0001077, GO:0001071, GO:0001047, GO:2000648, GO:0000975, GO:2000685, GO:2000774, GO:0035978, GO:0035985, GO:0035988, GO:0035986, GO:0035987, GO:2001022, GO:2001033, GO:2001038, GO:0031052, GO:0035500, GO:0035501, GO:0071141, GO:0090276, GO:0090402 |
| InterPro Term |
AT_hook_DNA-bd_motif, HMGI/HMGY, AT_hook-like |
| InterPro ID |
IPR017956, IPR000116, IPR020478 |
| Gene Ontology Term |
cell division, DNA binding, negative regulation of transcription, DNA-dependent, negative regulation of DNA binding, protein binding, regulation of transcription, DNA-dependent, nucleosomal DNA binding, stem cell differentiation, positive regulation of cell proliferation, positive regulation of gene expression, negative regulation of apoptosis, DNA-(apurinic or apyrimidinic site) lyase activity, nuclear chromosome, spermatogenesis, male gonad development, DNA bending activity, positive regulation of multicellular organism growth, positive regulation of apoptosis, transcription factor binding, cell cycle, positive regulation of transcription from RNA polymerase II promoter, multicellular organismal development, nucleus, somatic stem cell maintenance, mitosis, SMAD binding, chromatin, base-excision repair, negative regulation of transcription from RNA polymerase II promoter, chromosome condensation, chromatin organization, epithelial to mesenchymal transition, positive regulation of transcription, DNA-dependent, heterochromatin formation, regulation of growth, AT DNA binding, DNA damage response, detection of DNA damage, mesenchymal cell differentiation, pituitary gland development, cell proliferation in forebrain, adipose tissue development, chondrocyte differentiation, adrenal gland development, fat cell differentiation, C2H2 zinc finger domain binding, mitotic cell cycle G2/M transition DNA damage checkpoint, negative regulation by host of viral transcription, protein-DNA complex, response to virus, mesodermal cell differentiation, 5'-deoxyribose-5-phosphate lyase activity, negative regulation of astrocyte differentiation, regulation of growth hormone secretion, positive regulation of cell cycle arrest, DNA-dependent protein kinase activity, cAMP response element binding, mesodermal-endodermal cell signaling, regulation of stem cell maintenance, regulation of cell cycle process, negative regulation of retroviral genome replication, fat pad development, protein binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, core promoter binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, positive regulation of transcription regulatory region DNA binding, nucleic acid binding transcription factor activity, positive regulation of stem cell proliferation, regulatory region DNA binding, SMAD protein complex, positive regulation of cellular senescence, MH1 domain binding, chromosome breakage, regulation of peptide hormone secretion, senescence-associated heterochromatin focus formation, regulation of cellular response to drug, endodermal cell differentiation, MH2 domain binding, positive regulation of response to DNA damage stimulus, histone H2A-S139 phosphorylation, positive regulation of cellular response to X-ray, negative regulation of double-strand break repair via nonhomologous end joining, chondrocyte proliferation, senescence-associated heterochromatin focus, oncogene-induced senescence |
| Description |
high mobility group AT-hook 2 [Source:HGNC Symbol;Acc:5009] |
| HGNC Symbol |
HMGA2 |
| Gene-Disease Assocation |
LIPOMATOSIS, MULTIPLE, STATURE QUANTITATIVE TRAIT LOCUS 9; STQTL9, LEIOMYOMA, UTERINE; UL |
| EMBL-Bank ID |
AF326972, X92518, AC090673, U28750, U28749, U28754, U28753, U28752, U28751, L41044, AC107308, L46353, Z31595, L44578, AY601862, AY601861, AY601864, AY601863, AY601867, EU263620 |
| Ensembl Family |
ENSFM00600000925410 |
| Ensembl Family Description |
HMGA2EHMGA2E' |
| UniProt Accession |
B2KX87, Q8IZX8, Q1M185, Q1M182, Q1M188, Q1M187, Q1M186, P52926, F5H2A4, F5H6H0, F5H2U8 |
| RefSeq ID |
NP_003475, NP_003474, NM_003484, NM_003483 |
| Ensembl Protein ID |
ENSP00000346658, ENSP00000377206, ENSP00000377205, ENSP00000407306, ENSP00000384026, ENSP00000439317, ENSP00000437747, ENSP00000437621, ENSP00000443372, ENSP00000440919 |
| Entrez Gene ID |
8091 |
| Ensembl Gene ID |
ENSG00000149948 |
| Ensembl Transcript ID |
ENST00000403681, ENST00000545998, ENST00000536545, ENST00000537429, ENST00000537275, ENST00000393578, ENST00000393577, ENST00000539662, ENST00000354636, ENST00000425208, ENST00000541363 |
| UniGene ID |
Hs.505924 |
| Design Element |
1561633_at, ENST00000541363, 1568287_at, 1558683_a_at, 69224_at, ENST00000354636, ENST00000393578, ENST00000393577, ENST00000537275, 1558682_at, 1567224_at, Hs2.385265.1.S1_3p_at, ENST00000536545, ENST00000537429, X92518_s_at, 35200_at, ENST00000425208, ENST00000545998, U28749_s_at, Hs2.196151.1.A1_3p_at, Hs2.434264.1.S1_3p_at, ENST00000539662, L46353_at, g6631086_3p_at, g6631086_3p_s_at, ENST00000403681, 208025_s_at, Hs2.385267.1.S1_3p_at, 638_at |
| Search EB-eye |
ENSG00000149948
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