NTRK2
close
Please copy/paste those URLs into your code to get same results in machine-readable formats:
|
Homo sapiens |
|
NTRK2 is differentially expressed in 296 experiments: 217 organism parts: liver, cerebellum, ... (215 more);, 204 disease states: normal, glioblastoma, ... (202 more);, 81 cell types 295 cell lines 34 compound treatments and 80 other conditions. |
| Synonyms |
TRKB |
| Orthologs |
Q0VCN4_BOVIN
(Bos taurus)
Ntrk2
(Rattus norvegicus)
F1P2E2_CHICK
(Gallus gallus)
ntrk2a
(Danio rerio)
ntrk2b
(Danio rerio)
Ntrk2
(Mus musculus)
sev
(Drosophila melanogaster)
ENSXETG00000004874
(Xenopus laevis)
ntrk2
(Xenopus laevis)
Q6JDI7_CANFA
(Canis familiaris)
ENSCAFG00000001380
(Canis familiaris)
(Compare orthologs)
|
| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR000372, IPR000483, IPR007110, IPR020635, IPR003598, IPR003599, IPR013098, IPR020777, IPR020455 |
| Gene Ontology Term |
cytosol, plasma membrane, protein binding, axon, membrane, Golgi membrane, regulation of dendrite development, protein tyrosine kinase activity, transmembrane receptor protein tyrosine kinase signaling pathway, cell differentiation, terminal button, ATP binding, multicellular organismal development, integral to plasma membrane, feeding behavior, postsynaptic density, regulation of metabolic process, axon terminus, dendrite, dendritic spine, growth cone, receptor activity, nucleotide binding, kinase activity, protein serine/threonine kinase activity, transmembrane receptor protein tyrosine kinase activity, nervous system development, glutamate secretion, cell surface, presynaptic active zone, protein kinase activity, activation of adenylate cyclase activity, regulation of neurotransmitter secretion, neuronal cell body, neurotrophin binding, brain-derived neurotrophic factor receptor signaling pathway, mechanoreceptor differentiation, vasculogenesis, brain-derived neurotrophic factor binding, excitatory synapse, neurotrophin receptor activity, positive regulation of synaptic transmission, glutamatergic, nerve growth factor receptor signaling pathway, retinal rod cell development, protein autophosphorylation, protein phosphorylation |
| InterPro Term |
Cys-rich_flank_reg_C, Ig_sub, LRR-contain_N, Prot_kinase_cat_dom, Ig-like, Ig_sub2, Ig_I-set, Tyr_kin_neurotrophic_rcpt_2, Tyr_kinase_NGF_rcpt, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Gene Ontology ID |
GO:0009986, GO:0016020, GO:0007169, GO:0007190, GO:0007275, GO:0016301, GO:0007399, GO:0048786, GO:0007631, GO:0030425, GO:0030426, GO:0030424, GO:0004713, GO:0004714, GO:0005524, GO:0014069, GO:0005515, GO:0014047, GO:0004872, GO:0043679, GO:0005886, GO:0005887, GO:0005829, GO:0004672, GO:0004674, GO:0050773, GO:0006468, GO:0043025, GO:0000166, GO:0000139, GO:0046777, GO:0019222, GO:0046928, GO:0043197, GO:0043195, GO:0030154, GO:0048011, GO:0060076, GO:0042490, GO:0048403, GO:0005030, GO:0051968, GO:0043121, GO:0001570, GO:0046548, GO:0031547 |
| Ensembl Family |
ENSFM00260000050374 |
| Ensembl Family Description |
3 GROWTH RECEPTOR PRECURSOR EC_2.7.10.1 GP145 TRK NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE TYROSINE KINASE |
| EMBL-Bank ID |
AF410901, AF410902, AF410900, AF410898, AF410899, AF400441, AL596132, AL445532, U12140, CH471089, AF508964, AK294285, BC031835, S76474, S76473, AK289904, X75958, AL390777 |
| UniProt Accession |
Q8WXJ7, Q8WXJ8, Q8WXJ4, Q8WXJ5, Q548C2, Q16620, B4DFV9, Q5VWE5 |
| Ensembl Protein ID |
ENSP00000306167, ENSP00000365381, ENSP00000365387, ENSP00000365386, ENSP00000379207, ENSP00000379221, ENSP00000314586, ENSP00000277120, ENSP00000352906 |
| RefSeq ID |
NP_006171, NM_001007097, NM_001018066, NM_001018065, NM_001018064, NM_006180, NP_001007098, NP_001018074, NP_001018075, NP_001018076 |
| Entrez Gene ID |
4915 |
| HGNC Symbol |
NTRK2 |
| UniGene ID |
Hs.712776, Hs.494312, Hs.595176 |
| Ensembl Gene ID |
ENSG00000148053 |
| Description |
neurotrophic tyrosine kinase, receptor, type 2 [Source:HGNC Symbol;Acc:8032] |
| Ensembl Transcript ID |
ENST00000304053, ENST00000323115, ENST00000395866, ENST00000395882, ENST00000376208, ENST00000376213, ENST00000376214, ENST00000277120, ENST00000359847 |
| Gene-Disease Assocation |
OBESITY, HYPERPHAGIA, AND DEVELOPMENTAL DELAY |
| Design Element |
Hs.172717.0.A1_3p_at, Hs.47860.1.S1_3p_x_at, 214680_3p_at, ENST00000304053, ENST00000359847, Hs.298998.1.S2_3p_at, 62942_at, ENST00000376208, 214680_at, X75958_at, Hs.298998.1.S1_3p_at, ENST00000277120, 1354_at, 47469_at, 221795_at, ENST00000323115, 33182_at, 221796_at, ENST00000395882, g5453811_3p_at, 36042_at, ENST00000395866, 38280_s_at, Hs.47860.1.S1_3p_s_at, Hs.12569.0.A1_3p_at, ENST00000376214, 207152_at, ENST00000376213, Hs.47860.1.S1_3p_at, S76473_s_at, 1355_g_at, 236095_at, U12140_at |
| Search EB-eye |
ENSG00000148053
|
 Show more
properties
|
|
