GPC3
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Homo sapiens |
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GPC3 is differentially expressed in 195 experiments: 137 organism parts: liver, lung, ... (135 more);, 117 disease states: normal, lung adenocarcinoma, ... (115 more);, 55 cell types 204 cell lines 23 compound treatments and 65 other conditions. |
| Synonyms |
SGBS, OCI-5, SDYS, SGB, DGSX, SGBS1 |
| Orthologs |
Q3ZBZ6_BOVIN
(Bos taurus)
gpc3
(Danio rerio)
Gpc3
(Rattus norvegicus)
Gpc3
(Mus musculus)
F1N8X1_CHICK
(Gallus gallus)
dally
(Drosophila melanogaster)
A9ULF4_XENTR
(Xenopus laevis)
GPC3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0009887, GO:0009948, GO:0008285, GO:0016020, GO:0009653, GO:0030513, GO:0005615, GO:0005515, GO:0005576, GO:0005578, GO:0005886, GO:0005887, GO:0005764, GO:0031225, GO:0040008, GO:0050680, GO:0043395, GO:0045926, GO:0045807, GO:0045879, GO:0045880, GO:0046658, GO:0060422, GO:0010171, GO:0072111, GO:0072180, GO:0046326, GO:0090090, GO:0045732, GO:0001822, GO:0001658, GO:0060976, GO:0030316, GO:0030324, GO:0030282, GO:0035116, GO:0072203, GO:2000096 |
| Gene Ontology Term |
plasma membrane, protein binding, negative regulation of cell proliferation, extracellular space, negative regulation of smoothened signaling pathway, membrane, lysosome, proteinaceous extracellular matrix, positive regulation of BMP signaling pathway, anchored to plasma membrane, extracellular region, heparan sulfate proteoglycan binding, anchored to membrane, anterior/posterior axis specification, negative regulation of growth, anatomical structure morphogenesis, integral to plasma membrane, positive regulation of smoothened signaling pathway, positive regulation of endocytosis, negative regulation of epithelial cell proliferation, organ morphogenesis, regulation of growth, coronary vasculature development, peptidyl-dipeptidase inhibitor activity, kidney development, bone mineralization, branching involved in ureteric bud morphogenesis, embryonic hindlimb morphogenesis, positive regulation of protein catabolic process, body morphogenesis, positive regulation of glucose import, lung development, mesonephric duct morphogenesis, cell proliferation involved in kidney development, negative regulation of canonical Wnt receptor signaling pathway, osteoclast differentiation, cell proliferation involved in metanephros development, positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway |
| InterPro Term |
Glypican |
| InterPro ID |
IPR001863 |
| Ensembl Family Description |
GLYPICAN 3 PRECURSOR INTESTINAL OCI 5 |
| Ensembl Family |
ENSFM00500000270283 |
| Description |
glypican 3 [Source:HGNC Symbol;Acc:4451] |
| EMBL-Bank ID |
AL662851, L47176, L47125, L47124, AL034401, U50410, AL009174, Z99570, Z97196, AF003529, AL008712, Z37987, AC002420 |
| Entrez Gene ID |
2719 |
| Ensembl Protein ID |
ENSP00000359854, ENSP00000377836, ENSP00000385307, ENSP00000444222 |
| UniGene ID |
Hs.644108, Hs.626762 |
| HGNC Symbol |
GPC3 |
| RefSeq ID |
NP_001158089, NP_001158090, NM_001164618, NM_001164617, NM_004484, NP_004475, NP_001158091, NM_001164619 |
| Ensembl Gene ID |
ENSG00000147257 |
| UniProt Accession |
C9JLE3, B1AJP6, P51654 |
| Ensembl Transcript ID |
ENST00000543339, ENST00000406757, ENST00000370818, ENST00000394299 |
| Gene-Disease Assocation |
WILMS TUMOR 1; WT1, SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 1; SGBS1 |
| Design Element |
g1237180_3p_at, ENST00000406757, 209220_at, L47125_s_at, 39350_at, Z37987_s_at, ENST00000394299, ENST00000370818, ENST00000543339 |
| Search EB-eye |
ENSG00000147257
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