ABL2
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Homo sapiens |
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ABL2 is differentially expressed in 267 experiments: 122 organism parts: bone marrow, hypothalamus, ... (120 more);, 184 disease states: normal, breast carcinoma, ... (182 more);, 81 cell types 361 cell lines 38 compound treatments and 73 other conditions. |
| Synonyms |
ARG, ABLL |
| Orthologs |
ABL2
(Bos taurus)
ENSCING00000003255
(Ciona intestinalis)
abl2
(Danio rerio)
Abl2
(Mus musculus)
ABL2
(Gallus gallus)
Abl
(Drosophila melanogaster)
abl2
(Xenopus laevis)
ABL2
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001452, IPR011511, IPR001245, IPR017442, IPR000719, IPR000980, IPR015015, IPR020635, IPR013247 |
| Gene Ontology Term |
cytosol, regulation of cell adhesion, protein binding, actin monomer binding, cytoplasm, actin filament bundle assembly, peptidyl-tyrosine phosphorylation, protein tyrosine kinase activity, actin filament organization, regulation of autophagy, ATP binding, magnesium ion binding, axon guidance, actin cytoskeleton, transferase activity, transferring phosphorus-containing groups, protein modification process, manganese ion binding, nucleotide binding, protein serine/threonine kinase activity, actin filament binding, non-membrane spanning protein tyrosine kinase activity, signal transduction, protein kinase activity, cellular response to retinoic acid, positive regulation of neuron projection development, regulation of endocytosis, positive regulation of oxidoreductase activity, protein phosphorylation, regulation of cell motility, regulation of actin cytoskeleton reorganization |
| InterPro Term |
SH2, SH3_domain, F-actin_binding, Prot_kinase_cat_dom, SH3_2, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom, SH3_3 |
| Gene Ontology ID |
GO:0003785, GO:0010506, GO:0007015, GO:0007165, GO:0007411, GO:0051015, GO:0051017, GO:0016772, GO:0004713, GO:0004715, GO:0005524, GO:0005515, GO:0005737, GO:0015629, GO:0005829, GO:0004672, GO:0004674, GO:0006468, GO:0006464, GO:0000166, GO:0018108, GO:0000287, GO:0030155, GO:0030145, GO:0051353, GO:0030100, GO:0071300, GO:0010976, GO:2000145, GO:2000249 |
| Ensembl Family |
ENSFM00570000851013 |
| EMBL-Bank ID |
AL512326, FJ542286, FJ542285, FJ542284, FJ542283, DQ009672, AL359179, M35296, BX538317, CH471067, AL139132, BC065912 |
| Entrez Gene ID |
27 |
| Description |
v-abl Abelson murine leukemia viral oncogene homolog 2 [Source:HGNC Symbol;Acc:77] |
| RefSeq ID |
NM_001168236, NM_001168237, NM_001168238, NM_001168239, NM_005158, NM_001136000, NM_001136001, NP_005149, NM_007314, NP_009298, NP_001129472, NP_001129473, NP_001161711, NP_001161710, NP_001161708, NP_001161709 |
| Ensembl Protein ID |
ENSP00000427562, ENSP00000339209, ENSP00000424697, ENSP00000426831, ENSP00000375897, ENSP00000423413, ENSP00000423578, ENSP00000356595, ENSP00000386152 |
| Ensembl Gene ID |
ENSG00000143322 |
| UniGene ID |
Hs.159472, Hs.614321, Hs.630545 |
| UniProt Accession |
P42684, D1MPS6, F8WAF7 |
| HGNC Symbol |
ABL2 |
| Ensembl Transcript ID |
ENST00000408940, ENST00000508127, ENST00000367623, ENST00000509520, ENST00000504324, ENST00000504405, ENST00000512653, ENST00000392043, ENST00000511413, ENST00000507173, ENST00000502732, ENST00000344730 |
| Ensembl Family Description |
TYROSINE KINASE EC_2.7.10.2 ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG ABELSON TYROSINE KINASE |
| Design Element |
Hs.159472.0.S1_3p_x_at, ENST00000344730, ENST00000502732, 231907_at, 53857_at, ENST00000392043, 62244_r_at, 226893_at, ENST00000408940, ENST00000504324, 62243_i_at, ENST00000509520, ENST00000507173, M35296_at, ENST00000508127, 1084_at, ENST00000367623, ENST00000512653, ENST00000511413, 206411_s_at, ENST00000504405, Hs.14763.0.A1_3p_at, 231907_3p_at, g6382061_3p_a_at |
| Search EB-eye |
ENSG00000143322
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