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HSPG2 Homo sapiens
HSPG2 is differentially expressed in 120 experiments [145 up/145 dn]: 44 organism parts: bone marrow [0 up/3 dn], heart [2 up/0 dn], ...; 40 disease states: normal [6 up/10 dn], glioblastoma [2 up/0 dn], ...; 37 cell types, 34 cell lines, 24 compound treatments and 19 other conditions.
Synonyms HSPG2, RP11-132G19.2-003, RP11-132G19.2-004, RP11-132G19.2-008, RP11-132G19.2-013, RP11-132G19.2-015, RP11-132G19.2-010, RP11-132G19.2-005
Orthologs him-4 (Caenorhabditis elegans)  Hspg2 (Mus musculus)  (Compare orthologs)
InterPro Term Concanavalin A-like lectin/glucanase, subgroup, EGF-like, EGF-like region, conserved site, EGF-like, type 2, Immunoglobulin subtype 2
Diseases Dyssegmental dysplasia, Silverman-Handmaker type, Schwartz-Jampel syndrome, type 1
GO Terms basal lamina, brain development, cardiac muscle tissue development, cell adhesion, embryonic skeletal system morphogenesis
Uniprot P98160  Q2VPA1  Q59EG0  Q5SZI6  Q5SZI9  Q5SZJ1  Q8TEU3  Q5SZJ2  Q5SZJ0  Q5SZI8  Q5SZI5 
Search EB-eye ENSG00000142798
REST API
Expression Summary
247 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
10
6
Stromal cell Cell type
4
None Compound treatment
2
2
Bone marrow Organism part
3
PC3 Cell line
2
Glioblastoma Disease state
2
Endothelial cell Cell type
2
N/a Test result
2
HL-60 Cell line
2
Breast carcinoma Disease state
2
Not applicable Histology
2
FLAP Compound treatment
2
Heart Organism part
2
Fibroblast Cell type
1
1
MK886 Compound treatment
2
HNRPA2B Compound treatment
2
Homo sapiens Organism
2
Epithelial cell Cell type
2
Prostate Organism part
2
Lung Organism part
1
1
Dermatomyositis Disease state
1
1
Ischemic cardiomyopathy Disease state
1
1
MCF-7 Cell line
1
1
Caudate nucleus Organism part
1
1
White blood cells Organism part
1
Organism_part Material type
1
Cell Material type
1
SW480 Cell line
1
SW620 Cell line
1
Grade IV Tumor grading
1
MCF7 Cell line
1
Pretreatment primary sample Clinical info
1
Glucocorticoid resistant Phenotype
1
Acute promyelocytic leukemia Disease state
1
U937 Cell line
1
Atrial mycocardium Organism part
1
Ventricular myocardium Organism part
1
Glucocorticoid sensitive Phenotype
1
Tumor Organism part
1
Kaposi's sarcoma-associated he... Infection
1
Rapamycin Compound treatment
1
Lymphatic endothelial cell Cell type
1
Fetal bovine serum in media Growth condition
1
Enzo Labeling Protocol type
1
Lymphoid tissue Organism part
1
ERalpha transfected Genotype
1
ERbeta transfected Genotype
1
T-cell lymphoblastic lymphoma Disease state
1
MCF10A Cell line
1
Hs746T Cell line
1
Vascular smooth muscle cell Cell type
1
TIVE Cell line
1
Chondrocyte Cell type
1
X-linked chronic granulomatous Disease state
1
HPL1 Cell line
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
Epilepsy Disease state
1
Lipopolysaccharide Compound treatment
1
SKBR3 Cell line
1
Benign prostatic hyperplasia Disease state
1
Prostate carcinoma Disease state
1
Primary cells Cell line
1
Inter-prandial lipid micelles ... Growth condition
1
ITS medium Growth condition
1
Postprandial lipid micelles in... Growth condition
1
ITS medium with albumin-bound ... Growth condition
1
Spermatid Cell type
1
Seminiferous tubule Organism part
1
HTERT/HPVE6/HPVE7/SV40t/hRas t... Gene modification
1
Epidermal keratinocyte Cell type
1
SkinEthic keratinocyte Cell type
1
Affymetrix Labeling Protocol type
1
Serum starvation synchronizati... Growth condition
1
Erythrocyte Cell type
1
Stage II Disease staging
1
Whole blood Organism part
1
Testis Organism part
1
Mononuclear cell Cell type
1
Skeletal muscle Organism part
1
Cartilage Organism part
1
Stage I Disease staging
1
No induction Protocol type
1
T-cell acute lymphoblastic leu... Disease state
1
Bladder carcinoma Disease state
1
Jurkat Cell line
1
Dimethyl sulfoxide Compound treatment
1
Brain Organism part
1
Macaca mulatta Organism
1
Age-related macular degenerati... Disease state
1
Primary blood vessel endotheli... Cell type
1
Skin substitute Cell type
1
Placebo Compound treatment
1
Glutamine Compound treatment
1
CodeLink Labeling Protocol type
1
MKN28 Cell line
1
Invasive ductal carcinoma Histology
1
Primary Disease staging
1
Olfactory bulb Organism part
1
Primary lymphatic endothelial ... Cell type
1
BJAB Cell line
1
BCBL-1 Cell line
1
Spermatocyte Cell type
1
HTERT/HPVE6/HPVE7/SV40t transf... Gene modification
1
Serum starvation + thymidine b... Growth condition
1
G2 Tumor grading
1
Adipose tissue Organism part
1
Placenta Organism part
1
Uterus Organism part
1
HTERT transfection Gene modification
1
Lymph node Organism part
1
Tonsil Organism part
1
Adipocyte Cell type
1
Control RNAi
1
SIM2s RNAi
1
BC-2 Cell line
1
None Gene modification
1
Gastric cancer Disease state
1
Duchenne muscular dystrophy Disease state
1
LANA induction Protocol type
1
Trigeminal ganglion Organism part
1
Hypothalamus Organism part
1
AIDS-KS, KSHV- Disease state
1
BT474 Cell line
1
Adipose-derived stem cell Cell type
1
KSHV infection Disease state
1
Hydroxyurea Compound treatment
1
Johnsen score count 2: Sertoli... Histology
1
HMEC184 Cell line
1
Fetal thyroid Organism part
1
TaN0M0 Disease staging
1
Media only Growth condition
1
SsMCF7 Cell line
1
Cardiac myocyte Cell type
1
Mannitol Compound treatment
1
Superficial transitional cell ... Disease state
1
Grade II Tumor grading
1
Smooth muscle Organism part
1
Duodenum Organism part
1
YCC10 Cell line
1
Decrease in CD4 cells Clinical history
1
Cystic change Histology
1
Wild_type Genotype
1
Hydrogen peroxide Compound treatment
1
Endothelial cell + pericyte Cell type
1
Monocyte Cell type
1
10 ng/ml LPS in media Growth condition
1
Appendix Organism part
1
Skin Organism part
1
CD34+ Cell type
1
SKMEL5 Cell line
1
Chronic myelogenous leukemia Disease state
1
Bacterial endotoxin Compound treatment
1
Control Compound treatment
1
Term Developmental stage
1
Midgestation Developmental stage
1
GLI56 Cell line
1
MDA-MB-231 Cell line
1
M2 macrophage Cell type
1
Vasectomized Clinical history
1
HMT3522S1 Cell line
1
Dorsal root ganglion Organism part
1
Frontal cortex, superior motor... Organism part
1
Mock induction Protocol type
1
T84 Cell line
1
Caco-2 Cell line
1
Thyroid Organism part
1
M-CSF Compound treatment
1
Mesenchymal stem cell Cell type
1
Hematopoietic stem cell Cell type
1
Adipose tissue-derived stem ce... Cell type
1
Plasma cell Cell type
1
B lymphocyte Cell type
1
Idiopathic dilated cardiomyopa... Disease state
1
KSHV latent infection Disease state
1
Vanadium pentoxide Compound treatment
1
Burkitt's lymphoma Disease state
1
Benign nevi Disease state
1
Carboplatin resistant Test result
1
Carboplatin sensitive Test result
1
GLI60 Cell line
1
IL-4 Compound treatment
1
Head and neck squamous cell ca... Disease state
1
AGS Cell line
1
Total_RNA Material type
1
Polysome-associated RNA Material type
1
B-precursor acute lymphoblasti... Disease state
1
Epidermal growth factor Compound treatment
1
White blood cell Cell type
1
Platelet Cell type
1
Pancreatic cancer Disease state
1
Clear cell sarcoma of the kidn... Disease state
1
Fetal lung Organism part
1
Adrenal cortex Organism part
1
Thymus Organism part
1
Mercaptopurine, methotrexate Compound treatment
1
Breast cancer Disease state
1
Oligodendroglioma Disease state
1
Adrenal gland Organism part
1
PCep4 control vector transfect... Gene modification
1
ETat plasmid transfection Gene modification
1
Secretory cell Cell type
1
Mercaptopurine Compound treatment
1
Ciliary ganglion Organism part
1
Salivary gland Organism part
1
Tumor cell Cell type
1
Mercury dichloride Compound treatment
1
Estrogen receptor 1 negative; ... Test result
1
Gorilla gorilla Organism
1
Acute lymphocytic leukemia Disease state
1
0 cm away from the tumor bound... Observation
1
ERalpha/beta transfected Genotype
1
Crohn's disease Disease state
1
Cerebellum Organism part
1
Met5A Cell line
1
5-aza-2'-deoxycytidine + trich... Compound treatment
1
Cigarette smoke Growth condition
1
Incubator control Growth condition
1
Primary gastric tumor Organism part
1
Whole brain Organism part
1
Monocyte at intermediate diffe... Cell type
1
Drug-naive Clinical treatment
1
Prostate cancer Disease state
1
Metastatic Disease staging
1
Lin- CD34- Phenotype
1
CD14+ monocyte Cell type
1
CD105+ endothelial Cell type
1
Kaposi's sarcoma Disease state
1
Trichostatin A Compound treatment
1
Acute malaria, natural infecti... Disease state
1
Pleura Organism part
1
Mock RNAi
1
M1 macrophage Cell type
1
Fetal brain Organism part
1
Cyclosporin A, mycophenolate m... Clinical treatment
1
Sirolimus, mycophenolate mofet... Clinical treatment
1
Methotrexate Compound treatment
1
STK3 overexpression Genotype
1
Carcinoma in situ lesion Disease state
1
AIDS-KS, HIV+, nodular (late) ... Disease state
1
267B1 Cell line
1
267B1_Ki-ras Cell line
1
CD4+ T-cell Cell type
1
MDA468 Cell line
1
Amygdala Organism part
1
Chronic pancreatitis Disease state
1
Ultraviolet light Light
1
Expression Profiles
E-GEOD-5258: Transcription profiling of human cell lines freely cycling treated with 164 distinct small molecules - Broad Connectivity Map CMAP Set 1
Experimental Factors
Show expression profile  /  experiment details

 
E-AFMX-5: Transcription profiling of human cell lines and tissues (GNF/Novartis)
Experimental Factors
Cell type Organism part Disease state
Show expression profile  /  experiment details

 
E-MEXP-455: Transcription profiling of human blood and lymphatic endothelial cells (BECs and LECs) with and without culture in order to evaluate the artefact of cell culture on the level of the transcriptome
Experimental Factors
Cell type Individual Material type
Show expression profile  /  experiment details

 
E-MEXP-1014: Transcription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-5824: Transcription profiling of human Acute Lymphoblastic Leukemia CEM_C1 cells treated with rapamycin identifies rapamycin as a glucocorticoid resistance reversal agent
Experimental Factors
Phenotype Time Clinical info Dose Compound treatment
Show expression profile  /  experiment details

 
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