PML
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Homo sapiens |
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PML is differentially expressed in 350 experiments: 182 organism parts: lung, heart, ... (180 more);, 275 disease states: normal, breast carcinoma, ... (273 more);, 99 cell types 511 cell lines 52 compound treatments and 89 other conditions. |
| Synonyms |
MYL, TRIM19, RNF71 |
| Orthologs |
PML
(Bos taurus)
ENSGALG00000001398
(Gallus gallus)
ENSGALG00000001478
(Gallus gallus)
Pml
(Mus musculus)
F1M589_RAT
(Rattus norvegicus)
XM_849154.1
(Canis familiaris)
ENSCAFG00000017858
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
response to UV, cytosol, negative regulation of cell growth, DNA binding, protein stabilization, negative regulation of mitotic cell cycle, maintenance of protein location in nucleus, endoplasmic reticulum, negative regulation of transcription, DNA-dependent, protein binding, regulation of transcription, DNA-dependent, cytokine-mediated signaling pathway, cytoplasm, DNA damage response, signal transduction resulting in induction of apoptosis, intracellular, negative regulation of cell proliferation, membrane, protein targeting, cell cycle arrest, metal ion binding, activation of caspase activity, transforming growth factor beta receptor signaling pathway, insoluble fraction, protein complex assembly, response to hypoxia, nuclear matrix, induction of apoptosis, transcription coactivator activity, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, nucleus, protein heterodimerization activity, cell fate commitment, endosome, protein homodimerization activity, SMAD binding, nucleoplasm, response to gamma radiation, nucleolus, nuclear membrane, zinc ion binding, ubiquitin protein ligase binding, SUMO binding, response to cytokine stimulus, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, extrinsic to endoplasmic reticulum membrane, cell aging, negative regulation of angiogenesis, negative regulation of translation in response to oxidative stress, PML body organization, negative regulation of telomerase activity, negative regulation of telomere maintenance via telomerase, endoplasmic reticulum calcium ion homeostasis, response to virus, early endosome membrane, positive regulation of defense response to virus by host, interspecies interaction between organisms, PML body, branching involved in mammary gland duct morphogenesis, cobalt ion binding, regulation of MHC class I biosynthetic process, positive regulation of histone deacetylation, retinoic acid receptor signaling pathway, myeloid cell differentiation, common-partner SMAD protein phosphorylation, regulation of protein phosphorylation, interferon-gamma-mediated signaling pathway, SMAD protein import into nucleus, regulation of calcium ion transport into cytosol, negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Gene Ontology ID |
GO:0003677, GO:0008285, GO:0008270, GO:0016020, GO:0003713, GO:0010332, GO:0009411, GO:0008630, GO:0007050, GO:0007179, GO:0016363, GO:0051457, GO:0031965, GO:0042803, GO:0005626, GO:0005622, GO:0042771, GO:0005515, GO:0006919, GO:0006917, GO:0005730, GO:0005737, GO:0005634, GO:0005654, GO:0005829, GO:0005783, GO:0005768, GO:0046332, GO:0006605, GO:0001932, GO:0006461, GO:0050821, GO:0031625, GO:0046872, GO:0006355, GO:0019221, GO:0046982, GO:0045930, GO:0045892, GO:0001666, GO:0045165, GO:0030308, GO:0032183, GO:0034097, GO:0060444, GO:0016605, GO:0016525, GO:0007182, GO:0007184, GO:0009615, GO:0007569, GO:0031901, GO:0030578, GO:0042406, GO:0048384, GO:0002230, GO:0006977, GO:0032469, GO:0051974, GO:0031065, GO:0050897, GO:0032938, GO:0044419, GO:0030099, GO:0045343, GO:0032211, GO:0060333, GO:0010522, GO:2000059 |
| InterPro ID |
IPR000315, IPR001841, IPR021978 |
| InterPro Term |
Znf_RING, Znf_B-box, DUF3583 |
| Ensembl Family |
ENSFM00250000002506 |
| Ensembl Protein ID |
ENSP00000315434, ENSP00000378567, ENSP00000378564, ENSP00000268059, ENSP00000268058, ENSP00000353004, ENSP00000394642, ENSP00000402146, ENSP00000395576, ENSP00000406709 |
| RefSeq ID |
NM_033247, NM_033246, NM_033244, NM_033240, NM_033239, NM_033238, NM_033250, NP_150253, NP_150250, NP_150249, NP_150247, NP_150241, NP_150243, NP_150242, NP_002666, NM_002675 |
| EMBL-Bank ID |
BT009911, M73778, X64800, BC020994, S50913, S68527, X63131, S51489, BC000080, M80185, AC013486, AB067754, M79464, M79463, M79462, AF230402, AF230403, AF230401, AF230406, AF230407, AF230405, AF230408, AF230409, AF230410, AF230411, AC108137, AB209411 |
| HGNC Symbol |
PML |
| UniGene ID |
Hs.526464 |
| UniProt Accession |
Q9UE85, P29590, Q05835, E9PBR7, F8W9X2 |
| Description |
promyelocytic leukemia [Source:HGNC Symbol;Acc:9113] |
| Entrez Gene ID |
5371 |
| Ensembl Gene ID |
ENSG00000140464 |
| Ensembl Family Description |
PML |
| Ensembl Transcript ID |
ENST00000436891, ENST00000268059, ENST00000268058, ENST00000417341, ENST00000395132, ENST00000395135, ENST00000418568, ENST00000354026, ENST00000435786, ENST00000359928 |
| Design Element |
239582_at, 566_at, 38788_at, ENST00000417341, 211014_s_at, 211588_s_at, Hs.258217.0.A1_3p_at, g190116_3p_at, 211012_s_at, ENST00000268059, ENST00000268058, 38787_at, ENST00000436891, ENST00000418568, ENST00000395135, M79462_at, M79463_s_at, ENST00000395132, ENST00000354026, 210362_x_at, X63131_s_at, 211013_x_at, g12275908_3p_s_at, g12275906_3p_s_at, 567_s_at, g4505902_3p_a_at, 206503_x_at, ENST00000435786, ENST00000359928 |
| Search EB-eye |
ENSG00000140464
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