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LHCGR Homo sapiens
LHCGR is differentially expressed in 56 experiments [52 up/51 dn]: 18 organism parts: kidney [0 up/1 dn], peripheral blood [1 up/0 dn], ...; 18 disease states: normal [7 up/0 dn], carcinoma in situ lesion [1 up/0 dn], ...; 10 cell types, 7 cell lines, 8 compound treatments and 13 other conditions.
Synonyms LCGR, LGR2, LHCGR, LHRHR
Orthologs Lhcgr (Mus musculus)  Fsh (Drosophila melanogaster)  LSHR_RAT (Rattus norvegicus)  (Compare orthologs)
InterPro Term 7TM GPCR, rhodopsin-like, GPCR, rhodopsin-like superfamily, Glycoprotein hormone receptor, Lutropin-choriogonadotropic hormone receptor, Leucine-rich repeat-containing N-terminal domain
Diseases Leydig cell adenoma, somatic, with precocious puberty, Leydig cell hypoplasia with hypergonadotropic hypogonadism, Leydig cell hypoplasia with pseudohermaphroditism, Precocious puberty, male, Luteinizing hormone resistance, female
GO Terms ATPase binding, G-protein signaling, coupled to cAMP nucleotide second messenger, activation of adenylate cyclase activity, arachidonic acid secretion, endosome
Uniprot P22888  Q4ZFZ4  Q53S49 
Search EB-eye ENSG00000138039
REST API
Expression Summary
91 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
7
None Compound treatment
2
1
FLAP Compound treatment
2
HNRPA2B Compound treatment
2
Epithelial cell Cell type
1
1
Homo sapiens Organism
2
SW620 Cell line
1
SW480 Cell line
1
Kidney Organism part
1
Peripheral blood Organism part
1
Heat-killed HL60 cell lysate Infection
1
Carcinoma in situ lesion Disease state
1
White blood cells Organism part
1
Methotrexate Compound treatment
1
Superficial transitional cell ... Disease state
1
Johnsen score count 2: Sertoli... Histology
1
Muscle invasive carcinoma Disease state
1
Serum starvation + thymidine b... Growth condition
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
Tumor Organism part
1
X-linked chronic granulomatous Disease state
1
Anaplasma phagocytophilum Infection
1
Caudate nucleus Organism part
1
Macaca mulatta Organism
1
Vasectomized Clinical history
1
Astrocyte Cell type
1
HeLa Cell line
1
Trigeminal ganglion Organism part
1
Organism_part Material type
1
Cell Material type
1
Ciliary ganglion Organism part
1
Fetal bovine serum in media Growth condition
1
Heat-killed Anaplasma phagocyt... Infection
1
Johnsen score count 3.2: Serto... Histology
1
Endothelial cell Cell type
1
Fibroblast Cell type
1
Serum starvation synchronizati... Growth condition
1
Superficial transitional cell ... Disease state
1
Invasive ductal carcinoma Histology
1
Lymphatic endothelial cell Cell type
1
Breast carcinoma Disease state
1
MCF-7 Cell line
1
Lung Organism part
1
Control RNAi
1
SIM2s RNAi
1
Monoclonal gammopathy of undet... Disease state
1
Atrioventricular node Organism part
1
Lymph node Organism part
1
HL-60 Cell line
1
Dorsal root ganglion Organism part
1
Atrial mycocardium Organism part
1
Ventricular myocardium Organism part
1
Training set Population
1
Test set Population
1
Macrophage Cell type
1
Monocyte Cell type
1
Stromal cell Cell type
1
Benign nevi Disease state
1
Not applicable Histology
1
N/a Test result
1
0 cm away from the tumor bound... Observation
1
Endometrioid carcinoma Disease state
1
Capra hircus Organism
1
Leydig cell Cell type
1
Baseline uninfected Disease state
1
Chronic lymphocytic leukemia Disease state
1
Skin Organism part
1
Cryptorchidism Clinical history
1
Acute promyelocytic leukemia Disease state
1
U937 Cell line
1
Cigarette smoke Growth condition
1
Incubator control Growth condition
1
IgV status unknown Genotype
1
Unknown_sex Sex
1
Malignant pleural mesothelioma Disease state
1
Valproic acid Compound treatment
1
Blood Organism part
1
Umbilical cord Organism part
1
Fetus Developmental stage
1
Adult Developmental stage
1
Subthalamic nucleus Organism part
1
Caco-2 Cell line
1
Bacterial endotoxin Compound treatment
1
Control Compound treatment
1
Testicular seminoma Disease state
1
Pancreas Organism part
1
Alveolar space neutrophil Cell type
1
Postprandial lipid micelles in... Growth condition
1
Acute malaria, natural infecti... Disease state
1
Platelet-derived growth factor Compound treatment
1
Expression Profiles
E-MEXP-1014: Transcription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-4646: Transcription profiling of human HUVEC cells infected with Neisseria meningitidis wild type and mutants vs uninfected sampled at 3 time points
Experimental Factors
Time Infection
Show expression profile  /  experiment details

 
E-GEOD-1563: Transcription profiling of human kidney and peripheral blood lymphocytes from kidney transplant patients
Experimental Factors
Clinical info Organism part
Show expression profile  /  experiment details

 
E-GEOD-935: Transcription profiling of human polymorphonuclear leukocytes (PMNs) from healthy individuals vs patients with X-linked chronic granulomatous disease
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-412: Transcription profiling of human leukemia cells treated with mercaptopurine and/or methotrexate
Experimental Factors
Dose Compound treatment
Show expression profile  /  experiment details

 
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