LHCGR
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Homo sapiens |
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LHCGR is differentially expressed in 118 experiments: 83 organism parts: dorsal root ganglion, lung, ... (81 more);, 68 disease states: normal, healthy, ... (66 more);, 29 cell types 48 cell lines 8 compound treatments and 56 other conditions. |
| Synonyms |
LGR2, LCGR, ULG5, LHR, HHG |
| Orthologs |
LHCGR
(Bos taurus)
Lhcgr
(Rattus norvegicus)
Lhcgr
(Mus musculus)
lhcgr
(Danio rerio)
F1NGD6_CHICK
(Gallus gallus)
Fsh
(Drosophila melanogaster)
LHCGR
(Xenopus laevis)
Q95MF7_CANFA
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002274, IPR000276, IPR017452, IPR002131, IPR002273 |
| Gene Ontology Term |
plasma membrane, endoplasmic reticulum, peptide receptor activity, G-protein coupled, cytoplasm, G-protein signaling, coupled to cAMP nucleotide second messenger, extracellular space, activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger, lysosome, male genitalia development, hormone-mediated signaling pathway, G-protein coupled receptor protein signaling pathway, spermatogenesis, male gonad development, female gonad development, signal transducer activity, identical protein binding, integral to plasma membrane, nucleus, receptor activity, endosome, response to drug, protein homodimerization activity, integral to membrane, protein targeting to lysosome, central nervous system development, activation of adenylate cyclase activity, peptide hormone binding, positive regulation of release of sequestered calcium ion into cytosol, luteinizing hormone receptor activity, development of secondary male sexual characteristics, ATPase binding, uterus development, G-protein signaling, coupled to cyclic nucleotide second messenger, ovulation cycle process, intrinsic to external side of plasma membrane, receptor complex, ovarian follicle development, positive regulation of calcium ion transport into cytosol, positive regulation of calcium-mediated signaling, regulation of steroid biosynthetic process, luteinizing hormone signaling pathway, positive regulation of hormone biosynthetic process, arachidonic acid secretion, seminiferous tubule development, ovum-producing ovary development, choriogonadotropin hormone receptor activity, regulation of steroid hormone biosynthetic process |
| InterPro Term |
GPCR_Rhodpsn_supfam, 7TM_GPCR_Rhodpsn, TSH_rcpt, Gphrmn_rcpt, LSH_rcpt |
| Gene Ontology ID |
GO:0016021, GO:0007186, GO:0007188, GO:0007190, GO:0007283, GO:0007200, GO:0009755, GO:0008528, GO:0008585, GO:0008584, GO:0007417, GO:0042493, GO:0030539, GO:0042803, GO:0042802, GO:0005615, GO:0004871, GO:0004872, GO:0005737, GO:0005634, GO:0005886, GO:0005887, GO:0005783, GO:0005768, GO:0005764, GO:0006622, GO:0010524, GO:0004964, GO:0060065, GO:0007187, GO:0051281, GO:0051117, GO:0042700, GO:0031233, GO:0050810, GO:0050850, GO:0046886, GO:0043235, GO:0001541, GO:0046544, GO:0050482, GO:0022602, GO:0017046, GO:0090030, GO:0035472, GO:0072520, GO:0061039 |
| Ensembl Family |
ENSFM00290000065523 |
| Ensembl Family Description |
FOLLICLE STIMULATING HORMONE RECEPTOR PRECURSOR FSH R FOLLITROPIN RECEPTOR |
| EMBL-Bank ID |
S57793, M73746, AF082076, M63108, AC087816, X84753, X84754, X84761, X84762, X84760, X84763, X84758, X84757, X84756, X84755, X84759, AF024642, AC073082 |
| Ensembl Protein ID |
ENSP00000412255, ENSP00000403748, ENSP00000385847, ENSP00000385406, ENSP00000344301, ENSP00000294954, ENSP00000386033 |
| Gene-Disease Assocation |
PRECOCIOUS PUBERTY, MALE-LIMITED, LEYDIG CELL HYPOPLASIA, TYPE I |
| UniProt Accession |
P22888, Q53S49, Q4ZFZ4, E7ENI1, E7EQB5, E7ESK4, E9PDH1, E3W981 |
| Description |
luteinizing hormone/choriogonadotropin receptor [Source:HGNC Symbol;Acc:6585] |
| Entrez Gene ID |
3973 |
| HGNC Symbol |
LHCGR |
| Ensembl Gene ID |
ENSG00000138039 |
| UniGene ID |
Hs.468490 |
| RefSeq ID |
NP_000224, NM_000233 |
| Ensembl Transcript ID |
ENST00000403273, ENST00000401907, ENST00000294954, ENST00000477576, ENST00000420913, ENST00000344775, ENST00000405626, ENST00000428232 |
| Design Element |
ENST00000401907, M73746_s_at, ENST00000405626, ENST00000344775, g4557716_3p_a_at, ENST00000294954, ENST00000403273, 32293_at, ENST00000420913, 32294_g_at, 207240_s_at, ENST00000428232, ENST00000477576 |
| Search EB-eye |
ENSG00000138039
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