THBS1
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Homo sapiens |
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THBS1 is differentially expressed in 408 experiments: 193 organism parts: lung, placenta, ... (191 more);, 285 disease states: normal, glioblastoma, ... (283 more);, 153 cell types 546 cell lines 56 compound treatments and 87 other conditions. |
| Synonyms |
TSP1, TSP, THBS-1, THBS, TSP-1 |
| Orthologs |
Q5VH52_CIOIN
(Ciona intestinalis)
THBS1
(Bos taurus)
Tsp
(Drosophila melanogaster)
THBS1 (2 of 2)
(Danio rerio)
thbs1
(Danio rerio)
Thbs1
(Mus musculus)
THBS1
(Gallus gallus)
thbs1
(Xenopus laevis)
THBS1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0009897, GO:0008201, GO:0007050, GO:0007155, GO:0016477, GO:0007596, GO:0042493, GO:0030511, GO:0042802, GO:0005615, GO:0005509, GO:0005515, GO:0005576, GO:0006916, GO:0006917, GO:0006955, GO:0005198, GO:0005178, GO:0040037, GO:0043066, GO:0031012, GO:0043154, GO:0000187, GO:0045727, GO:0018149, GO:0051895, GO:0050431, GO:0043499, GO:0001666, GO:0030141, GO:0034605, GO:0010748, GO:0010763, GO:0010757, GO:0010759, GO:0010596, GO:0010595, GO:0016525, GO:0009749, GO:0042327, GO:0048603, GO:0002544, GO:0002576, GO:0042535, GO:0005577, GO:0006954, GO:0002040, GO:0003417, GO:0032570, GO:0001937, GO:0001948, GO:0001953, GO:0001968, GO:0051918, GO:0032695, GO:0031091, GO:0050840, GO:0043032, GO:0045766, GO:0001786, GO:0043394, GO:0032914, GO:0051897, GO:0043236, GO:0043536, GO:0043537, GO:0051592, GO:0030169, GO:0030168, GO:0030194, GO:0030335, GO:0050921, GO:0032026, GO:0070052, GO:0010811, GO:0010754, GO:0010751, GO:0002605, GO:0002581, GO:0043652, GO:0070051, GO:0031093, GO:2000379 |
| Gene Ontology Term |
cell migration, stored secretory granule, protein binding, positive regulation of translation, extracellular space, heparin binding, negative regulation of apoptosis, eukaryotic cell surface binding, structural molecule activity, cell cycle arrest, extracellular region, blood coagulation, anti-apoptosis, response to hypoxia, positive regulation of transforming growth factor beta receptor signaling pathway, external side of plasma membrane, activation of MAPK activity, negative regulation of fibroblast growth factor receptor signaling pathway, transforming growth factor beta binding, identical protein binding, cell adhesion, induction of apoptosis, immune response, response to drug, integrin binding, cellular response to heat, extracellular matrix, calcium ion binding, peptide cross-linking, negative regulation of caspase activity, negative regulation of focal adhesion assembly, fibroblast growth factor 2 binding, positive regulation of cell-substrate adhesion, response to magnesium ion, negative regulation of fibrinolysis, negative regulation of blood vessel endothelial cell migration, platelet degranulation, growth plate cartilage development, negative regulation of angiogenesis, laminin binding, response to calcium ion, response to progesterone stimulus, fibrinogen complex, extracellular matrix binding, positive regulation of endothelial cell migration, positive regulation of cell migration, negative regulation of endothelial cell migration, phosphatidylserine binding, negative regulation of plasma membrane long-chain fatty acid transport, positive regulation of blood coagulation, positive regulation of chemotaxis, proteoglycan binding, positive regulation of phosphorylation, chronic inflammatory response, collagen V binding, sprouting angiogenesis, glycoprotein binding, negative regulation of plasminogen activation, inflammatory response, positive regulation of tumor necrosis factor biosynthetic process, response to glucose stimulus, platelet alpha granule, positive regulation of fibroblast migration, positive regulation of angiogenesis, negative regulation of cell-matrix adhesion, positive regulation of blood vessel endothelial cell migration, positive regulation of protein kinase B signaling cascade, negative regulation of interleukin-12 production, positive regulation of macrophage activation, positive regulation of macrophage chemotaxis, fibronectin binding, platelet activation, negative regulation of endothelial cell proliferation, engulfment of apoptotic cell, negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, fibrinogen binding, negative regulation of cGMP-mediated signaling, negative regulation of nitric oxide mediated signal transduction, negative regulation of dendritic cell antigen processing and presentation, platelet alpha granule lumen, low-density lipoprotein particle binding, positive regulation of reactive oxygen species metabolic process, positive regulation of transforming growth factor beta1 production |
| InterPro Term |
VWF_C, Laminin_G_thrombospondin_N, Thrombospondin_3-like_rpt, EGF_3, Thrombospondin_C, Thrombospondin_1_rpt, EGF-like, EGF-like_Ca-bd |
| InterPro ID |
IPR001007, IPR000742, IPR000884, IPR006210, IPR001881, IPR008859, IPR003129, IPR003367 |
| Ensembl Family Description |
PRECURSOR |
| Ensembl Family |
ENSFM00250000000689 |
| Description |
thrombospondin 1 [Source:HGNC Symbol;Acc:11785] |
| EMBL-Bank ID |
AK291639, AK293230, M14326, U12471, BC028145, M99425, X04665, J04835, X14787, AC037198, BC136470, BC136469, M25631 |
| UniProt Accession |
B4DDK8, P07996, A0PJG0, Q7KYY3, A8MZG1 |
| Ensembl Protein ID |
ENSP00000380721, ENSP00000380720, ENSP00000260356 |
| UniGene ID |
Hs.713837, Hs.599979, Hs.611774, Hs.164226 |
| RefSeq ID |
NM_003246, NP_003237 |
| Entrez Gene ID |
7057 |
| Ensembl Gene ID |
ENSG00000137801 |
| HGNC Symbol |
THBS1 |
| Ensembl Transcript ID |
ENST00000260356, ENST00000478845, ENST00000490247, ENST00000497720, ENST00000397593, ENST00000397591, ENST00000484734, ENST00000466755, ENST00000559746, ENST00000560894 |
| Design Element |
115_at, g4507484_3p_a_at, Hs.87409.0.A3_3p_a_at, 75740_at, X14787_at, ENST00000484734, Hs.247954.0.S1_3p_at, 215775_at, Hs.87409.0.A1_3p_a_at, 867_s_at, Hs.87409.0.A2_3p_a_at, ENST00000466755, 235086_at, 239336_at, Hs.42699.0.A1_3p_at, 53546_at, 201110_s_at, 201109_s_at, ENST00000560894, ENST00000559746, ENST00000497720, ENST00000260356, ENST00000478845, 866_at, ENST00000397593, 201107_s_at, Hs.164226.0.A1_3p_at, ENST00000490247, U12471_cds1_at, ENST00000397591, 201108_s_at |
| Search EB-eye |
ENSG00000137801
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