HMGA1
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Homo sapiens |
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HMGA1 is differentially expressed in 335 experiments: 136 organism parts: bone marrow, prostate, ... (134 more);, 240 disease states: normal, prostate carcinoma, ... (238 more);, 104 cell types 407 cell lines 46 compound treatments and 81 other conditions. |
| Synonyms |
HMGIY |
| Orthologs |
hmga1a
(Danio rerio)
Hmga1-rs1
(Mus musculus)
HMGA1
(Bos taurus)
Hmga1
(Mus musculus)
hmga1b
(Danio rerio)
RGD1564836
(Rattus norvegicus)
Hmga1
(Rattus norvegicus)
HMGA1_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003680, GO:0003677, GO:0008285, GO:0003700, GO:0003906, GO:0031936, GO:0005515, GO:0005694, GO:0005634, GO:0005654, GO:0005667, GO:0005829, GO:0000785, GO:0006461, GO:0019899, GO:0006355, GO:0006351, GO:0006284, GO:0006268, GO:0045892, GO:0045893, GO:0030374, GO:0016032, GO:0009615, GO:0042974, GO:0042975, GO:0006337, GO:0046965, GO:0044419, GO:0051575, GO:0019047, GO:0019059, GO:2000774, GO:0035985, GO:0035986, GO:0090402 |
| Gene Ontology Term |
negative regulation of chromatin silencing, cytosol, DNA binding, negative regulation of transcription, DNA-dependent, protein binding, regulation of transcription, DNA-dependent, negative regulation of cell proliferation, transcription, DNA-dependent, DNA-(apurinic or apyrimidinic site) lyase activity, protein complex assembly, transcription factor binding, nucleus, ligand-dependent nuclear receptor transcription coactivator activity, transcription factor complex, DNA unwinding involved in replication, chromosome, chromatin, nucleoplasm, base-excision repair, enzyme binding, positive regulation of transcription, DNA-dependent, AT DNA binding, viral reproduction, retinoid X receptor binding, peroxisome proliferator activated receptor binding, response to virus, interspecies interaction between organisms, 5'-deoxyribose-5-phosphate lyase activity, nucleosome disassembly, retinoic acid receptor binding, sequence-specific DNA binding transcription factor activity, provirus integration, initiation of viral infection, positive regulation of cellular senescence, senescence-associated heterochromatin focus formation, senescence-associated heterochromatin focus, oncogene-induced senescence |
| InterPro Term |
AT_hook_DNA-bd_motif, HMGI/HMGY, AT_hook-like |
| InterPro ID |
IPR017956, IPR000116, IPR020478 |
| HGNC Symbol |
HMGA1 |
| Ensembl Protein ID |
ENSP00000363230, ENSP00000378452, ENSP00000349871, ENSP00000288245, ENSP00000385693, ENSP00000318322, ENSP00000308227, ENSP00000399888 |
| RefSeq ID |
NM_145899, NM_145905, NM_145901, NM_145902, NM_145903, NP_665912, NP_665910, NP_665909, NP_665908, NP_665906, NP_002122, NM_002131 |
| Entrez Gene ID |
100130009, 3159 |
| EMBL-Bank ID |
L17131, AF176039, BC063434, BC004924, BC071864, BC067083, BC015789, M23619, M23618, M23614, M23615, M23616, M23617, X14958, X14957, AL354740, BT006774, BC008832 |
| Ensembl Gene ID |
ENSG00000137309 |
| Description |
high mobility group AT-hook 1 [Source:HGNC Symbol;Acc:5010] |
| UniProt Accession |
Q5T6U8, P17096 |
| Ensembl Family |
ENSFM00550000744988 |
| Ensembl Family Description |
MODERATELY SIMILAR TO HIGH MOBILITY GROUP HMG I/HMG Y |
| Ensembl Transcript ID |
ENST00000327014, ENST00000401473, ENST00000347617, ENST00000395004, ENST00000311487, ENST00000447654, ENST00000478214, ENST00000374116, ENST00000357318 |
| Gene-Disease Assocation |
DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM |
| Design Element |
g4504432_3p_x_at, 206074_s_at, ENST00000374116, 64363_f_at, ENST00000401473, g4504432_3p_s_at, 206074_3p_s_at, ENST00000478214, ENST00000311487, ENST00000447654, ENST00000395004, 39704_s_at, ENST00000327014, g5834272_3p_s_at, ENST00000347617, 210457_x_at, 210457_3p_x_at, L17131_rna1_at, ENST00000357318 |
| Search EB-eye |
ENSG00000137309
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